Gd-DTPA-coupled Ag2Se quantum dots for dual-modality magnetic resonance imaging and fluorescence imaging in the second near-infrared window

Nanoscale ◽  
2018 ◽  
Vol 10 (22) ◽  
pp. 10699-10704 ◽  
Author(s):  
Jiao-Jiao Ma ◽  
Ming-Xia Yu ◽  
Zheng Zhang ◽  
Wei-Guo Cai ◽  
Zhi-Ling Zhang ◽  
...  

Near-infrared (NIR) fluorescent quantum dots (QDs) are ideal platforms to fabricate multifunctional contrast agents for multimodal imaging.

Nanoscale ◽  
2014 ◽  
Vol 6 (15) ◽  
pp. 9264-9272 ◽  
Author(s):  
Gary Sitbon ◽  
Sophie Bouccara ◽  
Mariana Tasso ◽  
Aurélie Francois ◽  
Lina Bezdetnaya ◽  
...  

Cadmium-free quantum dots doped with Mn2+ions show promising results forin vivobimodal MRI and NIR fluorescence imaging.


2022 ◽  
Author(s):  
Doan Thi Kim Dung ◽  
Masakazu Umezawa ◽  
Kazunobu Ohnuki ◽  
Karina Nigoghossian ◽  
Kyohei Okubo ◽  
...  

Multimodal imaging can provide multidimensional information for understanding concealed microstructures or bioprocesses in biological objects. The combination of over–1000 nm near–infrared (OTN–NIR) fluorescence imaging and magnetic resonance (MR) imaging is...


Biomaterials ◽  
2014 ◽  
Vol 35 (5) ◽  
pp. 1608-1617 ◽  
Author(s):  
Ke Ding ◽  
Lihong Jing ◽  
Chunyan Liu ◽  
Yi Hou ◽  
Mingyuan Gao

2008 ◽  
pp. 5764 ◽  
Author(s):  
Takashi Jin ◽  
Yoshichika Yoshioka ◽  
Fumihiko Fujii ◽  
Yutaka Komai ◽  
Junji Seki ◽  
...  

2010 ◽  
Vol 46 (21) ◽  
pp. 3705 ◽  
Author(s):  
Kevin Guo ◽  
Mikhail Y. Berezin ◽  
Jie Zheng ◽  
Walter Akers ◽  
Franck Lin ◽  
...  

2021 ◽  
Vol 22 (1) ◽  
pp. 160-172
Author(s):  
Kyohei Okubo ◽  
Ryuta Takeda ◽  
Shuhei Murayama ◽  
Masakazu Umezawa ◽  
Masao Kamimura ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-14 ◽  
Author(s):  
William M. Payne ◽  
Tanner K. Hill ◽  
Denis Svechkarev ◽  
Megan B. Holmes ◽  
Balasrinivasa R. Sajja ◽  
...  

Surgical resection remains the most promising treatment strategy for many types of cancer. Residual malignant tissue after surgery, a consequence in part due to positive margins, contributes to high mortality and disease recurrence. In this study, multimodal contrast agents for integrated preoperative magnetic resonance imaging (MRI) and intraoperative fluorescence image-guided surgery (FIGS) are developed. Self-assembled multimodal imaging nanoparticles (SAMINs) were developed as a mixed micelle formulation using amphiphilic HA polymers functionalized with either GdDTPA for T1 contrast-enhanced MRI or Cy7.5, a near infrared fluorophore. To evaluate the relationship between MR and fluorescence signal from SAMINs, we employed simulated surgical phantoms that are routinely used to evaluate the depth at which near infrared (NIR) imaging agents can be detected by FIGS. Finally, imaging agent efficacy was evaluated in a human breast tumor xenograft model in nude mice, which demonstrated contrast in both fluorescence and magnetic resonance imaging.


Author(s):  
Linyun He ◽  
Yachao Zhang ◽  
Jiangbo Chen ◽  
Gongyuan Liu ◽  
Jingyi Zhu ◽  
...  

Early diagnosis and effective treatment of hepatocellular carcinoma (HCC) is quite critical for improving patients’ prognosis. The combination of second near-infrared window photoacoustic imaging (NIR-II PAI) and T2-magnetic resonance imaging...


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