scholarly journals The influence of Gd-DOTA ratios conjugating PLGA-PEG micelles encapsulated IR-1061 in bimodal over–1000 nm near–infrared fluorescence and magnetic resonance imaging

2022 ◽  
Author(s):  
Doan Thi Kim Dung ◽  
Masakazu Umezawa ◽  
Kazunobu Ohnuki ◽  
Karina Nigoghossian ◽  
Kyohei Okubo ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Mr Imaging ◽  
Fluorescence Imaging ◽  
Multimodal Imaging ◽  
Near Infrared ◽  
Resonance Imaging ◽  
Biological Objects ◽  
Nir Fluorescence ◽  
Multidimensional Information

Multimodal imaging can provide multidimensional information for understanding concealed microstructures or bioprocesses in biological objects. The combination of over–1000 nm near–infrared (OTN–NIR) fluorescence imaging and magnetic resonance (MR) imaging is...

scholarly journals Multimodal Mn-doped I–III–VI quantum dots for near infrared fluorescence and magnetic resonance imaging: from synthesis to in vivo application

Nanoscale ◽  
2014 ◽  
Vol 6 (15) ◽  
pp. 9264-9272 ◽  
Author(s):  
Gary Sitbon ◽  
Sophie Bouccara ◽  
Mariana Tasso ◽  
Aurélie Francois ◽  
Lina Bezdetnaya ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Quantum Dots ◽  
Magnetic Resonance ◽  
Fluorescence Imaging ◽  
Near Infrared ◽  
Resonance Imaging ◽  
Near Infrared Fluorescence ◽  
Nir Fluorescence ◽  
Mn Doped

Cadmium-free quantum dots doped with Mn2+ions show promising results forin vivobimodal MRI and NIR fluorescence imaging.

Gd-DTPA-coupled Ag2Se quantum dots for dual-modality magnetic resonance imaging and fluorescence imaging in the second near-infrared window

Nanoscale ◽  
2018 ◽  
Vol 10 (22) ◽  
pp. 10699-10704 ◽  
Author(s):  
Jiao-Jiao Ma ◽  
Ming-Xia Yu ◽  
Zheng Zhang ◽  
Wei-Guo Cai ◽  
Zhi-Ling Zhang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Quantum Dots ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Fluorescence Imaging ◽  
Multimodal Imaging ◽  
Near Infrared ◽  
Resonance Imaging ◽  
Dual Modality ◽  
Infrared Window

Near-infrared (NIR) fluorescent quantum dots (QDs) are ideal platforms to fabricate multifunctional contrast agents for multimodal imaging.

scholarly journals Near infrared-fluorescent and magnetic resonance imaging molecular probe with high T1 relaxivity for in vivo multimodal imaging

2010 ◽  
Vol 46 (21) ◽  
pp. 3705 ◽  
Author(s):  
Kevin Guo ◽  
Mikhail Y. Berezin ◽  
Jie Zheng ◽  
Walter Akers ◽  
Franck Lin ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Multimodal Imaging ◽  
Near Infrared ◽  
Molecular Probe ◽  
Resonance Imaging

Fabrication of transferrin modified two-photon gold nanoclusters with near-infrared fluorescence and its application for bioimaging

2021 ◽  
Author(s):  
Kangdi He ◽  
Shengrong Yu ◽  
Xiao Wang ◽  
Dian Li ◽  
Jia Chen ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Near Infrared ◽  
Gold Nanoclusters ◽  
Living Cells ◽  
Resonance Imaging ◽  
Near Infrared Fluorescence ◽  
Two Photon ◽  
Nir Fluorescence

Transferrin modified AuNCs (Tf-AuNCs) with TP-NIR fluorescence was prepared, and a novel nanoprobe platform Tf-AuNCs@MnO2 was developed for effectively TP-NIR fluorescence and magnetic resonance imaging of living cells and tissues...

Terbium-doped gadolinium oxide nanoparticles prepared by laser ablation in liquid for use as a fluorescence and magnetic resonance imaging dual-modal contrast agent

2015 ◽  
Vol 17 (2) ◽  
pp. 1189-1196 ◽  
Author(s):  
Fei Chen ◽  
Min Chen ◽  
Chuan Yang ◽  
Jun Liu ◽  
Ningqi Luo ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Laser Ablation ◽  
Magnetic Resonance ◽  
Mr Imaging ◽  
Contrast Agent ◽  
Fluorescence Imaging ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Laser Ablation In Liquid ◽  
Promising Candidate

Gd2O3:Tb is a promising candidate for use as a dual-modal contrast agent combining fluorescence imaging with MR imaging.

scholarly journals Multimodal Imaging Nanoparticles Derived from Hyaluronic Acid for Integrated Preoperative and Intraoperative Cancer Imaging

2017 ◽  
Vol 2017 ◽  
pp. 1-14 ◽  
Author(s):  
William M. Payne ◽  
Tanner K. Hill ◽  
Denis Svechkarev ◽  
Megan B. Holmes ◽  
Balasrinivasa R. Sajja ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Multimodal Imaging ◽  
Near Infrared ◽  
Xenograft Model ◽  
Disease Recurrence ◽  
Tumor Xenograft ◽  
Fluorescence Signal ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Mri

Surgical resection remains the most promising treatment strategy for many types of cancer. Residual malignant tissue after surgery, a consequence in part due to positive margins, contributes to high mortality and disease recurrence. In this study, multimodal contrast agents for integrated preoperative magnetic resonance imaging (MRI) and intraoperative fluorescence image-guided surgery (FIGS) are developed. Self-assembled multimodal imaging nanoparticles (SAMINs) were developed as a mixed micelle formulation using amphiphilic HA polymers functionalized with either GdDTPA for T1 contrast-enhanced MRI or Cy7.5, a near infrared fluorophore. To evaluate the relationship between MR and fluorescence signal from SAMINs, we employed simulated surgical phantoms that are routinely used to evaluate the depth at which near infrared (NIR) imaging agents can be detected by FIGS. Finally, imaging agent efficacy was evaluated in a human breast tumor xenograft model in nude mice, which demonstrated contrast in both fluorescence and magnetic resonance imaging.

scholarly journals A Gadolinium(III) Complex Based on the Thymine Nucleobase with Properties Suitable for Magnetic Resonance Imaging

2021 ◽  
Vol 22 (9) ◽  
pp. 4586
Author(s):  
Marta Orts-Arroyo ◽  
Amadeo Ten-Esteve ◽  
Sonia Ginés-Cárdenas ◽  
Isabel Castro ◽  
Luis Martí-Bonmatí ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Mr Imaging ◽  
Lesion Detection ◽  
Resonance Imaging ◽  
X Ray Diffraction ◽  
Functional Images ◽  
High Relaxivity ◽  
Contrast Enhanced ◽  
Phantom Studies

The paramagnetic gadolinium(III) ion is used as contrast agent in magnetic resonance (MR) imaging to improve the lesion detection and characterization. It generates a signal by changing the relaxivity of protons from associated water molecules and creates a clearer physical distinction between the molecule and the surrounding tissues. New gadolinium-based contrast agents displaying larger relaxivity values and specifically targeted might provide higher resolution and better functional images. We have synthesized the gadolinium(III) complex of formula [Gd(thy)2(H2O)6](ClO4)3·2H2O (1) [thy = 5-methyl-1H-pyrimidine-2,4-dione or thymine], which is the first reported compound based on gadolinium and thymine nucleobase. 1 has been characterized through UV-vis, IR, SEM-EDAX, and single-crystal X-ray diffraction techniques, and its magnetic and relaxometric properties have been investigated by means of SQUID magnetometer and MR imaging phantom studies, respectively. On the basis of its high relaxivity values, this gadolinium(III) complex can be considered a suitable candidate for contrast-enhanced magnetic resonance imaging.

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