scholarly journals Simultaneous multiple single nucleotide polymorphism detection based on click chemistry combined with DNA-encoded probes

2018 ◽  
Vol 9 (13) ◽  
pp. 3335-3340 ◽  
Author(s):  
Qian-Yu Zhou ◽  
Fang Yuan ◽  
Xiao-Hui Zhang ◽  
Ying-Lin Zhou ◽  
Xin-Xiang Zhang
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Click Reaction ◽  
High Sensitivity ◽  
Dna Ligase ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide Polymorphism Detection ◽  
Single Nucleotide ◽  
Polymorphism Detection ◽  
Novel Strategy ◽  
Dna Template

A novel strategy utilizing a DNA template-directed CuAAC click reaction to mimic a ligation reaction based on DNA ligase was successfully established for multiple SNP detection with high sensitivity and specificity.

scholarly journals Electrochemical sensor with dry reagents implemented in lab-on-chip for single nucleotide polymorphism detection

2014 ◽  
Vol 53 (5S1) ◽  
pp. 05FS03 ◽  
Author(s):  
Hiroyuki Tanaka ◽  
Paolo Fiorini ◽  
Benjamin Jones ◽  
Sara Peters ◽  
Rodrigo S. Wiederkehr ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Electrochemical Sensor ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide Polymorphism Detection ◽  
Single Nucleotide ◽  
Lab On Chip ◽  
Polymorphism Detection ◽  
On Chip

scholarly journals Multiplex real-time single nucleotide polymorphism detection and quantification by quencher extension

BioTechniques ◽  
2006 ◽  
Vol 40 (3) ◽  
pp. 323-329 ◽  
Author(s):  
Knut Rudi ◽  
Monika Zimonja ◽  
Sigrun E. Hannevik ◽  
Signe M. Drømtorp
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Real Time ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide Polymorphism Detection ◽  
Single Nucleotide ◽  
Polymorphism Detection ◽  
Detection And Quantification

Real time hybridization studies by resonant waveguide gratings using nanopattern imaging for Single Nucleotide Polymorphism detection

2013 ◽  
Vol 16 (2) ◽  
pp. 287-299 ◽  
Author(s):  
Kristelle Bougot-Robin ◽  
Rimantas Kodzius ◽  
Weisheng Yue ◽  
Longqing Chen ◽  
Shunbo Li ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Real Time ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide Polymorphism Detection ◽  
Single Nucleotide ◽  
Polymorphism Detection ◽  
Waveguide Gratings

Single-nucleotide polymorphism detection using nanomolar nucleotides and single-molecule fluorescence

2004 ◽  
Vol 327 (1) ◽  
pp. 35-44 ◽  
Author(s):  
Charles R. Twist ◽  
Michael K. Winson ◽  
Jem J. Rowland ◽  
Douglas B. Kell
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Single Molecule ◽  
Nucleotide Polymorphism ◽  
Single Molecule Fluorescence ◽  
Single Nucleotide Polymorphism Detection ◽  
Single Nucleotide ◽  
Polymorphism Detection

scholarly journals Facile functionalization of peptide nucleic acids (PNAs) for antisense and single nucleotide polymorphism detection

2017 ◽  
Vol 15 (32) ◽  
pp. 6710-6714 ◽  
Author(s):  
Digvijay Gahtory ◽  
Merita Murtola ◽  
Maarten M. J. Smulders ◽  
Tom Wennekes ◽  
Han Zuilhof ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Nucleic Acids ◽  
Peptide Nucleic Acids ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide Polymorphism Detection ◽  
Single Nucleotide ◽  
Polymorphism Detection ◽  
Detection Strategies

In this report, we show how a convenient on-resin copper-click functionalization of azido-functionalized peptide nucleic acids (PNAs) allows various PNA-based detection strategies.

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