Label-free and sensitive detection of coralyne and heparin based on target-induced G-quadruplex formation

2019 ◽  
Vol 11 (10) ◽  
pp. 1331-1337 ◽  
Author(s):  
Mingjian Chen ◽  
Changbei Ma ◽  
Han Zhao ◽  
Kemin Wang
Keyword(s):  
Detection Method ◽  
Sensitive Detection ◽  
Label Free ◽  
G Quadruplex ◽  
Quadruplex Formation

Herein we propose a label-free and sensitive detection method for coralyne and heparin, based on utilizing the complex of adenosine16 (A16) and coralyne to induce the formation of a G-quadruplex scaffold.

A label-free biosensor for selective detection of DNA and Pb2+ based on a G-quadruplex

RSC Advances ◽  
2016 ◽  
Vol 6 (10) ◽  
pp. 7765-7771 ◽  
Author(s):  
Ruipeng Hou ◽  
Xiaoqing Niu ◽  
Fengling Cui
Keyword(s):  
Detection Method ◽  
Selective Detection ◽  
Label Free ◽  
Schematic Representation ◽  
G Quadruplex

Schematic representation of the DNA and Pb2+ detection method.

A label-free DNAzyme fluorescence biosensor for amplified detection of Pb2+-based on cleavage-induced G-quadruplex formation

Talanta ◽  
2016 ◽  
Vol 147 ◽  
pp. 302-306 ◽  
Author(s):  
Ting Fu ◽  
Songlei Ren ◽  
Liang Gong ◽  
Hongmin Meng ◽  
Liang Cui ◽  
...  
Keyword(s):  
Label Free ◽  
G Quadruplex ◽  
Quadruplex Formation ◽  
Fluorescence Biosensor

scholarly journals G-Quadruplex formation using fluorescent oligonucleotides as a detection method for discriminating AGG trinucleotide repeats

2016 ◽  
Vol 52 (86) ◽  
pp. 12757-12760 ◽  
Author(s):  
Yoojin Park ◽  
Ki Tae Kim ◽  
Byeang Hyean Kim
Keyword(s):  
Detection Method ◽  
Oligonucleotide Probe ◽  
Trinucleotide Repeats ◽  
Enhanced Fluorescence ◽  
Background Signal ◽  
Low Background ◽  
G Quadruplex ◽  
Quadruplex Formation

A fluorescent oligonucleotide probe induces the formation of intermolecular G-quadruplexes with AGG trinucleotide repeats. The probe also exhibits 35.0- and 44.7-fold enhanced fluorescence signals for DNA AGG and RNA agg repeat oligonucleotides with respect to the low background signal.

A label-free fluorescence method for the detection of uracil DNA glycosylase activity based on G-quadruplex formation

2016 ◽  
Vol 8 (41) ◽  
pp. 7453-7459 ◽  
Author(s):  
Changbei Ma ◽  
Kefeng Wu ◽  
Jun Wang ◽  
Hailun He ◽  
Feng Ning ◽  
...  
Keyword(s):  
Fluorescence Method ◽  
Thioflavin T ◽  
Dna Glycosylase ◽  
Label Free ◽  
Uracil Dna Glycosylase ◽  
Label Free Detection ◽  
G Quadruplex ◽  
Quadruplex Formation

A simple fluorescence based biosensor for label-free detection of uracil DNA glycosylase activity based on G-quadruplex formation using a thioflavin T probe is reported.

Label-free fluorescence light-up detection of T4 polynucleotide kinase activity using the split-to-intact G-quadruplex strategy by ligation-triggered and toehold-mediated strand displacement release

The Analyst ◽  
2015 ◽  
Vol 140 (16) ◽  
pp. 5450-5453 ◽  
Author(s):  
Lu Zhou ◽  
Xiaoqiang Shen ◽  
Na Sun ◽  
Kewei Wang ◽  
Yuanyuan Zhang ◽  
...  
Keyword(s):  
Kinase Activity ◽  
Detection Method ◽  
Label Free ◽  
Strand Displacement ◽  
Polynucleotide Kinase ◽  
G Quadruplex ◽  
Fluorescence Light ◽  
T4 Polynucleotide Kinase

A label-free, fluorescence light-up detection method for T4 polynucleotide kinase activity has been developed using the split-to-intact G-quadruplex strategy.

Turn-on and label-free fluorescence detection of lead ions based on target-induced G-quadruplex formation

2015 ◽  
Vol 51 (38) ◽  
pp. 8165-8168 ◽  
Author(s):  
Lijun Xu ◽  
Xiaoqiang Shen ◽  
Shanni Hong ◽  
Jine Wang ◽  
Yuanyuan Zhang ◽  
...  
Keyword(s):  
Fluorescence Detection ◽  
High Sensitivity ◽  
Lead Ions ◽  
Label Free ◽  
Low Background ◽  
Background Fluorescence ◽  
Turn On ◽  
Sensing Systems ◽  
G Quadruplex ◽  
Quadruplex Formation

Using a guanine-rich sequence (AGRO100) and N-methyl mesoporphyrin IX (NMM), a turn-on and label-free fluorescent Pb2+ sensor with high sensitivity and low background fluorescence was presented as a representative of five turn-on sensing systems.

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