Bifunctional supramolecular prodrug vesicles constructed from a camptothecin derivative with a water-soluble pillar[5]arene for cancer diagnosis and therapy

2019 ◽  
Vol 55 (73) ◽  
pp. 10892-10895 ◽  
Author(s):  
Guangping Sun ◽  
Zhimei He ◽  
Min Hao ◽  
Zuqiang Xu ◽  
Xiao-Yu Hu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Anticancer Drug ◽  
Cancer Diagnosis ◽  
Water Soluble ◽  
Tumor Diagnosis ◽  
Anticancer Drug Delivery ◽  
Diagnosis And Therapy ◽  
Cancer Diagnosis And Therapy

Bifunctional supramolecular prodrug nanocarriers have been successfully constructed for efficient anticancer drug delivery and tumor diagnosis and therapy.

Diblock brush-arm star copolymers via a core-first/graft-from approach using γ-cyclodextrin and ROMP: a modular platform for drug delivery

2020 ◽  
Vol 11 (2) ◽  
pp. 541-550 ◽  
Author(s):  
Ruihan Li ◽  
Xuesong Li ◽  
Yipei Zhang ◽  
Abigail O. Delawder ◽  
Nathan D. Colley ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Anticancer Drug ◽  
Ring Opening ◽  
Water Soluble ◽  
Ring Opening Metathesis Polymerization ◽  
Metathesis Polymerization ◽  
Anticancer Drug Delivery ◽  
Star Copolymers ◽  
Modular Platform

Water-soluble diblock brush-arm star copolymers using γ-CD-based core-first ring-opening metathesis polymerization, allowing for anticancer drug delivery via host–guest interaction.

scholarly journals Recent Advancements in Serum Albumin-Based Nanovehicles Toward Potential Cancer Diagnosis and Therapy

2021 ◽  
Vol 9 ◽  
Author(s):  
Xue Shen ◽  
Xiyang Liu ◽  
Tingting Li ◽  
Yin Chen ◽  
Yang Chen ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Serum Albumin ◽  
Cancer Diagnosis ◽  
Drug Loading ◽  
Essential Information ◽  
Drug Delivery Vehicles ◽  
Albumin Nanoparticles ◽  
Diagnosis And Therapy ◽  
Delivery Vehicles ◽  
Cancer Diagnosis And Therapy

Recently, drug delivery vehicles based on nanotechnology have significantly attracted the attention of researchers in the field of nanomedicine since they can achieve ideal drug release and biodistribution. Among the various organic or inorganic materials that used to prepare drug delivery vehicles for effective cancer treatment, serum albumin-based nanovehicles have been widely developed and investigated due to their prominent superiorities, including good biocompatibility, high stability, nontoxicity, non-immunogenicity, easy preparation, and functionalization, allowing them to be promising candidates for cancer diagnosis and therapy. This article reviews the recent advances on the applications of serum albumin-based nanovehicles in cancer diagnosis and therapy. We first introduce the essential information of bovine serum albumin (BSA) and human serum albumin (HSA), and discuss their drug loading strategies. We then discuss the different types of serum albumin-based nanovehicles including albumin nanoparticles, surface-functionalized albumin nanoparticles, and albumin nanocomplexes. Moreover, after briefly discussing the application of serum albumin-based nanovehicles used as the nanoprobes in cancer diagnosis, we also describe the serum albumin-based nanovehicle-assisted cancer theranostics, involving gas therapy, chemodynamic therapy (CDT), phototherapy (PTT/PDT), sonodynamic therapy (SDT), and other therapies as well as cancer imaging. Numerous studies cited in our review show that serum albumin-based nanovehicles possess a great potential in cancer diagnostic and therapeutic applications.

A glutathione-depleted prodrug platform of MnO2-coated hollow polydopamine nanospheres for effective cancer diagnosis and therapy

2020 ◽  
Vol 44 (19) ◽  
pp. 7838-7848
Author(s):  
Liang Dong ◽  
Zhiai Xu ◽  
Shangjie An ◽  
Xiaodan Jia ◽  
Wen Zhang ◽  
...  
Keyword(s):  
Manganese Oxide ◽  
Cancer Diagnosis ◽  
Tumor Diagnosis ◽  
Diagnosis And Treatment ◽  
Diagnosis And Therapy ◽  
Cancer Diagnosis And Therapy

A biocompatible and efficient nanoplatform for tumor diagnosis and treatment was fabricated based on manganese oxide-coated hollow polydopamine loaded with dihydroartemisinin.

Dendrimer nanoarchitectures for cancer diagnosis and anticancer drug delivery

2017 ◽  
Vol 22 (2) ◽  
pp. 314-326 ◽  
Author(s):  
Ashok Kumar Sharma ◽  
Avinash Gothwal ◽  
Prashant Kesharwani ◽  
Hashem Alsaab ◽  
Arun K. Iyer ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Anticancer Drug ◽  
Cancer Diagnosis ◽  
Anticancer Drug Delivery

Methoxy polyethylene glycol–cholesterol modified soy lecithin liposomes for poorly water‐soluble anticancer drug delivery

2020 ◽  
Vol 138 (7) ◽  
pp. 49858
Author(s):  
Ngoc Thuy Trang Le ◽  
Dinh Tien Dung Nguyen ◽  
Ngoc Hoi Nguyen ◽  
Cuu Khoa Nguyen ◽  
Dai Hai Nguyen
Keyword(s):  
Drug Delivery ◽  
Polyethylene Glycol ◽  
Anticancer Drug ◽  
Water Soluble ◽  
Soy Lecithin ◽  
Anticancer Drug Delivery ◽  
Poorly Water Soluble ◽  
Methoxy Polyethylene Glycol

Multifunctional carbon nanomateriels for camptothecine low-water soluble anticancer drug delivery

2018 ◽  
Vol 42 (2) ◽  
pp. 1326-1336 ◽  
Author(s):  
Asma Itatahine ◽  
Yamina Ait Mehdi ◽  
Meriem Fizir ◽  
Man Qi ◽  
Pierre Dramou ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Graphene Oxide ◽  
Anticancer Drug ◽  
Water Soluble ◽  
Magnetic Graphene Oxide ◽  
Hybrid Nanomaterial ◽  
Anticancer Drug Delivery ◽  
Magnetic Carbon ◽  
Magnetic Carbon Nanotubes

A multifunctional hybrid nanomaterial of magnetic graphene oxide (GO) and magnetic carbon nanotubes (CNTs) was ensheathed with mesoporous silica, for the loading and delivery of an anticancer drug, camptothecine (CPT).

Dual CD44 and folate receptor-targeted nanoparticles for cancer diagnosis and anticancer drug delivery

2016 ◽  
Vol 236 ◽  
pp. 38-46 ◽  
Author(s):  
Jae-Young Lee ◽  
Ubonvan Termsarasab ◽  
Ju-Hwan Park ◽  
Song Yi Lee ◽  
Seung-Hak Ko ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Anticancer Drug ◽  
Cancer Diagnosis ◽  
Folate Receptor ◽  
Targeted Nanoparticles ◽  
Anticancer Drug Delivery
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