A flavonoid-based fluorescent probe enables the accurate quantification of human serum albumin by minimizing the interference from blood lipids

2019 ◽  
Vol 55 (93) ◽  
pp. 13983-13986 ◽  
Author(s):  
Kangning Zhu ◽  
Taoyuze Lv ◽  
Tianyi Qin ◽  
Yingying Huang ◽  
Lei Wang ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Fluorescent Probe ◽  
Blood Lipids ◽  
Design Strategy ◽  
Simple Design ◽  
Polarity Sensitive ◽  
Accurate Quantification

We herein provide a simple design strategy to improve the sensing specificity towards human serum albumin by incorporating a nitrobenzene quencher into a traditional polarity-sensitive probe in responding to the interference from blood lipids.

Interaction between a novel intramolecular charge transfer fluorescent probe PFEP and human serum albumin

2010 ◽  
Vol 21 (4) ◽  
pp. 480-483 ◽  
Author(s):  
Dong Ju ◽  
Sheng Mei Song ◽  
Yan Bo Wu ◽  
Shao Min Shuang ◽  
Chuan Dong
Keyword(s):  
Charge Transfer ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Fluorescent Probe ◽  
Intramolecular Charge Transfer

A fluorescent probe for butyrylcholinesterase activity in human serum based on a fluorophore with specific binding affinity for human serum albumin

2019 ◽  
Vol 55 (97) ◽  
pp. 14574-14577 ◽  
Author(s):  
Soyeon Yoo ◽  
Min Su Han
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Fluorescent Probe ◽  
Binding Affinity ◽  
Specific Binding ◽  
Turn On ◽  
High Binding ◽  
Butyrylcholinesterase Activity ◽  
High Binding Affinity

We report a novel turn-on sensing probe for the detection of butyrylcholinesterase activity in human serum using a fluorophore with high binding affinity for HSA.

scholarly journals A Near Infrared Fluorescent Probe for Sensitive Determination of Human Serum Albumin

2016 ◽  
Vol 32 (12) ◽  
pp. 1291-1294 ◽  
Author(s):  
Xiaodan ZENG ◽  
Mingshuo MA ◽  
Baocun ZHU ◽  
Lin ZHU
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Fluorescent Probe ◽  
Near Infrared ◽  
Sensitive Determination

A novel hydrazide Schiff base self-assembled nanoprobe for selective detection of human serum albumin and its applications in renal disease surveillance

2020 ◽  
Vol 8 (36) ◽  
pp. 8346-8355
Author(s):  
Zhi-Gang Wang ◽  
Xiao-Jing Yan ◽  
Hai-Bo Liu ◽  
De-Long Zhang ◽  
Wei Liu ◽  
...  
Keyword(s):  
Schiff Base ◽  
Human Serum Albumin ◽  
Renal Disease ◽  
Serum Albumin ◽  
Human Serum ◽  
Fluorescent Probe ◽  
Disease Surveillance ◽  
Selective Detection ◽  
Binding Mechanism ◽  
Site Binding

A novel fluorescent probe based on disassembly-induced emission and the site-binding mechanism for HSA detection and applications in renal disease surveillance.

scholarly journals Protein encapsulation: a new approach for improving the capability of small-molecule fluorogenic probes

2020 ◽  
Vol 11 (4) ◽  
pp. 1107-1113 ◽  
Author(s):  
Hai-Hao Han ◽  
Adam C. Sedgwick ◽  
Ying Shang ◽  
Na Li ◽  
Tingting Liu ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Fluorescent Probe ◽  
Small Molecule ◽  
Protein Encapsulation ◽  
New Approach ◽  
Fluorogenic Probes ◽  
Guest Chemistry

Herein, we report a protein-based hybridization strategy that exploits the host–guest chemistry of HSA (human serum albumin) to solubilize the otherwise cell impermeable ONOO− fluorescent probe Pinkment-OAc.

scholarly journals 7-Alkylaminocoumarin-4-acetic acids as fluorescent probe for studies of drug-binding sites on human serum albumin.

1991 ◽  
Vol 39 (3) ◽  
pp. 724-728 ◽  
Author(s):  
Mitsuru IRIKURA ◽  
Akira TAKADATE ◽  
Shujiro GOYA ◽  
Masaki OTAGIRI
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Fluorescent Probe ◽  
Binding Sites ◽  
Drug Binding ◽  
Drug Binding Sites ◽  
Acetic Acids

A TICT based NIR-fluorescent probe for human serum albumin: a pre-clinical diagnosis in blood serum

2016 ◽  
Vol 52 (6) ◽  
pp. 1182-1185 ◽  
Author(s):  
Shahi Imam Reja ◽  
Imran A. Khan ◽  
Vandana Bhalla ◽  
Manoj Kumar
Keyword(s):  
Detection Limit ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Blood Serum ◽  
Blood Plasma ◽  
Human Serum ◽  
Fluorescent Probe ◽  
Clinical Diagnosis ◽  
Fluorescence Enhancement ◽  
In Blood Plasma

A TICT based NIR-fluorescent probe3has been designed and synthesized which selectively detects HSA with fluorescence enhancement in blood plasma with a detection limit of 11 nM among the various proteins, nucleotides and thiols tested.

Sign in / Sign up

Export Citation Format

Share Document