Doxorubicin-reinforced supramolecular hydrogels of RGD-derived peptide conjugates for pH-responsive drug delivery

2019 ◽  
Vol 17 (15) ◽  
pp. 3853-3860 ◽  
Author(s):  
Leixia Mei ◽  
Keming Xu ◽  
Ziran Zhai ◽  
Suyun He ◽  
Tingting Zhu ◽  
...  

Doxorubicin reinforced the self-assembly of RGD-derived peptide conjugates responsive to mild acidity.

2018 ◽  
Vol 54 (4) ◽  
pp. 401-404 ◽  
Author(s):  
R. Otter ◽  
K. Klinker ◽  
D. Spitzer ◽  
M. Schinnerer ◽  
M. Barz ◽  
...  

ABA′ triblock peptide–polysarcosine–peptide conjugates fold into antiparallel β-sheets, which promotes the self-assembly into polysarcosine-shielded core–shell nanorods with protein repellent properties.


2013 ◽  
Vol 21 (5) ◽  
pp. 415-426 ◽  
Author(s):  
Jiangxiu Niu ◽  
Aiwen Huang ◽  
Yanyu Xiao ◽  
Zhigui Su ◽  
Hongying Li ◽  
...  

RSC Advances ◽  
2016 ◽  
Vol 6 (4) ◽  
pp. 2571-2581 ◽  
Author(s):  
Yinwen Li ◽  
Xiuwen Zheng ◽  
Kun Wu ◽  
Mangeng Lu

Schematic illustrations of the self-assembly of TGCs and possible loading and release mechanism.


2013 ◽  
Vol 705 ◽  
pp. 115-119
Author(s):  
Bao Yong Tian ◽  
Er Jun Tang ◽  
Miao Yuan ◽  
Rui Xia Hao ◽  
Cun Man Li ◽  
...  

The well-defined block copolymer PMMA-b-PS was prepared by two-step ATRP in emulsion system. GPC results indicate that Mn increased linearly with conversion and polydispersity remained relatively narrow. It presents the characteristics of living polymerization in emulsion system. FT-IR demonstrated that block copolymer PMMA-b-PS could be successfully synthesized by ATRP with macroinitiator PMMA-Cl in emulsion system. The morphological characteristic of the self-assembly depends on the block copolymer concentration and transforms between spheres and rodlike micelles. The property indicates a perfect potential application in drug delivery materials.


AIChE Journal ◽  
2008 ◽  
Vol 54 (11) ◽  
pp. 2979-2989 ◽  
Author(s):  
Youqing Shen ◽  
Yihong Zhan ◽  
Jianbin Tang ◽  
Peisheng Xu ◽  
Patrick A. Johnson ◽  
...  

2020 ◽  
Vol 11 (16) ◽  
pp. 2811-2821 ◽  
Author(s):  
Yudian Qiu ◽  
Zongyuan Zhu ◽  
Yalei Miao ◽  
Panke Zhang ◽  
Xu Jia ◽  
...  

The polymerization of dopamine and its coupling occur in succession, which synergistically induces the self-assembly of block copolymer to yield ordered structures, including micelles and vesicles.


2014 ◽  
Vol 50 (85) ◽  
pp. 12933-12936 ◽  
Author(s):  
Clara Morita-Imura ◽  
Yoshiro Imura ◽  
Takeshi Kawai ◽  
Hitoshi Shindo

The pH-responsive self-assembly of a zwitterionic amphiphile was expanded to the recovery of gold (Au) nanoparticles. Multilayered lamellae were incorporated into the nanoparticles. Redispersion of nanoparticles was achieved by the transition of self-assembly based on pH.


2016 ◽  
Vol 4 (48) ◽  
pp. 8025-8032 ◽  
Author(s):  
D. Sirisha Janni ◽  
U. Chandrasekhar Reddy ◽  
Soumya Saroj ◽  
K. M. Muraleedharan

The self-assembly of non-ionic amphiphiles with hydroxylated oxanorbornane head-group was controlled using amino acid units as spacers between hydrophilic and lipophilic domains to get spherical supramolecular aggregates suitable for drug delivery applications.


2015 ◽  
Vol 3 (4) ◽  
pp. 627-635 ◽  
Author(s):  
Tao Peng ◽  
Hwankyu Lee ◽  
Sierin Lim

Controlling the self-assembly behavior of caged proteins expands their potential applications in nanotechnology.


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