scholarly journals Substrate-rigidity dependent migration of an idealized twitching bacterium

Soft Matter ◽  
2019 ◽  
Vol 15 (30) ◽  
pp. 6224-6236
Author(s):  
Ahmet Nihat Simsek ◽  
Andrea Braeutigam ◽  
Matthias D. Koch ◽  
Joshua W. Shaevitz ◽  
Yunfei Huang ◽  
...  
Keyword(s):  
Analytical Model ◽  
Surface Adhesion ◽  
Physical Mechanisms ◽  
Substrate Rigidity ◽  
Rigidity Dependence ◽  
Cellular Motion

An analytical model reveals generic physical mechanisms for substrate-rigidity dependence of cellular motion. Key ingredients are a tight surface adhesion and forced adhesion rupture.

scholarly journals Tandem tension sensor reveals substrate rigidity-dependence of integrin molecular tensions in live cells

2020 ◽  
Author(s):  
Anwesha Sarkar ◽  
Dana LeVine ◽  
Yuanchang Zhao ◽  
Keyvan Mollaeian ◽  
Juan Ren ◽  
...  
Keyword(s):  
Live Cells ◽  
Force Level ◽  
Ligand Density ◽  
Rigidity Sensing ◽  
Substrate Rigidity ◽  
Molecular Force ◽  
Elastic Substrates ◽  
Tension Sensor ◽  
Rigidity Dependence ◽  
Activation Probability

AbstractResponse of integrin tensions to substrate rigidity is important in cell rigidity sensing but has not been confirmed. Current fluorescent tension sensors produce cellular force signals collectively resulted from integrin tension magnitude, tension dwell time, integrin density and activity, ligand density and accessibility, etc., making it challenging to monitor the absolute molecular force level of integrin tensions in live cells. Here we developed a tandem tension sensor (TTS) consisting of two coupled tension sensing units which are subject to the same tension and respond with different activation probabilities to the tension. Reported by fluorescence, the activation probability ratio of these two units solely responds to the force level of local integrin tensions, excluding the bias from other non-force factors. We verified the feasibility of TTS in detecting integrin tensions and applied it to study cells on elastic substrates. TTS unambiguously reported that integrin tensions in platelets decrease monotonically with the substrate rigidity, verifying the rigidity-dependence of integrin tensions in live cells.

Strain analysis with nanometer resolution using a conventional transmission electron microsopy technique: electron diffraction contrast imaging revisited

1995 ◽  
Vol 53 ◽  
pp. 168-169
Author(s):  
Koenraad G F Janssens ◽  
Omer Van der Biest ◽  
Jan Vanhellemont ◽  
Herman E Maes ◽  
Robert Hull
Keyword(s):  
Electron Diffraction ◽  
Strain Field ◽  
Elastic Strain ◽  
Strain Analysis ◽  
Local Strain ◽  
Contrast Imaging ◽  
Strain Characterization ◽  
Physical Mechanisms ◽  
Diffraction Contrast ◽  
Transmission Electron

There is a growing need for elastic strain characterization techniques with submicrometer resolution in several engineering technologies. In advanced material science and engineering the quantitative knowledge of elastic strain, e.g. at small particles or fibers in reinforced composite materials, can lead to a better understanding of the underlying physical mechanisms and thus to an optimization of material production processes. In advanced semiconductor processing and technology, the current size of micro-electronic devices requires an increasing effort in the analysis and characterization of localized strain. More than 30 years have passed since electron diffraction contrast imaging (EDCI) was used for the first time to analyse the local strain field in and around small coherent precipitates1. In later stages the same technique was used to identify straight dislocations by simulating the EDCI contrast resulting from the strain field of a dislocation and comparing it with experimental observations. Since then the technique was developed further by a small number of researchers, most of whom programmed their own dedicated algorithms to solve the problem of EDCI image simulation for the particular problem they were studying at the time.

An analytical model for conflict dynamics

1997 ◽  
Vol 48 (10) ◽  
pp. 978-987
Author(s):  
N Gass
Keyword(s):  
Analytical Model

Simple quasi-two-dimensional analytical model to characterise the electric field in an LDD MOSFET

1990 ◽  
Vol 137 (4) ◽  
pp. 291
Author(s):  
R.H. Patel ◽  
D.-L. Kwong ◽  
N. Herr
Keyword(s):  
Electric Field ◽  
Analytical Model ◽  
Two Dimensional

ANALYTICAL MODEL OF SUPEREXCHANGE

1988 ◽  
Vol 49 (C8) ◽  
pp. C8-911-C8-912
Author(s):  
Yu. V. Rakitin ◽  
V. T. Kalinnikov
Keyword(s):  
Analytical Model

Coding Algorithm for Grayscale Images – Design of Piecewise Uniform Quantizer with Golomb–Rice Code and Novel Analytical Model for Performance Analysis

Informatica ◽  
2017 ◽  
Vol 28 (4) ◽  
pp. 703-724 ◽  
Author(s):  
Nikola Simić ◽  
Zoran H. Perić ◽  
Milan S. Savić
Keyword(s):  
Performance Analysis ◽  
Analytical Model ◽  
Grayscale Images

Injecting Inter-Layers and the Built-in Potential of Blue Polymer Light-Emitting Diodes

2000 ◽  
Vol 660 ◽  
Author(s):  
Thomas M. Brown ◽  
Ian S. Millard ◽  
David J. Lacey ◽  
Jeremy H. Burroughes ◽  
Richard H. Friend ◽  
...  
Keyword(s):  
Indium Tin Oxide ◽  
Light Emitting Diodes ◽  
Basic Structure ◽  
Thin Layers ◽  
Carrier Injection ◽  
Semiconducting Polymer ◽  
Light Emitting ◽  
Physical Mechanisms ◽  
Organic Solid ◽  
Polymer Light Emitting Diodes

ABSTRACTThe semiconducting-polymer/injecting-electrode heterojunction plays a crucial part in the operation of organic solid state devices. In polymer light-emitting diodes (LEDs), a common fundamental structure employed is Indium-Tin-Oxide/Polymer/Al. However, in order to fabricate efficient devices, alterations to this basic structure have to be carried out. The insertion of thin layers, between the electrodes and the emitting polymer, has been shown to greatly enhance LED performance, although the physical mechanisms underlying this effect remain unclear. Here, we use electro-absorption measurements of the built-in potential to monitor shifts in the barrier height at the electrode/polymer interface. We demonstrate that the main advantage brought about by inter-layers, such as poly(ethylenedioxythiophene)/poly(styrene sulphonic acid) (PEDOT:PSS) at the anode and Ca, LiF and CsF at the cathode, is a marked reduction of the barrier to carrier injection. The electro- absorption results also correlate with the electroluminescent characteristics of the LEDs.

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