Self-destructive PEG–BODIPY nanomaterials for photodynamic and photothermal therapy

2019 ◽  
Vol 7 (30) ◽  
pp. 4655-4660 ◽  
Author(s):  
Chaonan Li ◽  
Wenhai Lin ◽  
Shi Liu ◽  
Wei Zhang ◽  
Zhigang Xie
Keyword(s):  
Reactive Oxygen Species ◽  
Ethylene Glycol ◽  
Photothermal Therapy ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Poly Ethylene Glycol ◽  
Boron Dipyrromethene ◽  
Poly Ethylene

Amphiphilic photosensitizers are made from boron dipyrromethene and poly(ethylene glycol) by using a thioketal linker, which is reactive oxygen species-responsive for photodynamic and photothermal therapy.

A reactive oxygen species–responsive prodrug micelle with efficient cellular uptake and excellent bioavailability

2018 ◽  
Vol 6 (7) ◽  
pp. 1076-1084 ◽  
Author(s):  
Long Xu ◽  
Yidi Yang ◽  
Mingying Zhao ◽  
Wenxia Gao ◽  
Hai Zhang ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Drug Delivery Systems ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Stimuli Responsive ◽  
Poly Ethylene Glycol ◽  
Polymeric Drug Delivery ◽  
Polymeric Drug ◽  
Poly Ethylene ◽  
Polymeric Drug Delivery Systems

Stimuli-responsive polymeric drug delivery systems are of great interest in anticancer research. Here, a reactive oxygen species (ROS)–responsive prodrug was prepared by thioketal linkage of poly(ethylene glycol) (PEG) and the anticancer drug doxorubicin (DOX).

scholarly journals Performance of Polydopamine Complex and Mechanisms in Wound Healing

2021 ◽  
Vol 22 (19) ◽  
pp. 10563
Author(s):  
Dantong Zheng ◽  
Chongxing Huang ◽  
Xuhao Zhu ◽  
Haohe Huang ◽  
Chenglong Xu
Keyword(s):  
Reactive Oxygen Species ◽  
Wound Healing ◽  
Photothermal Therapy ◽  
Drug Loading ◽  
Reactive Oxygen ◽  
Wound Dressings ◽  
Inflammatory Factors ◽  
Oxygen Species ◽  
Self Healing

Polydopamine (PDA) has been gradually applied in wound healing of various types in the last three years. Due to its rich phenol groups and unique structure, it can be combined with a variety of materials to form wound dressings that can be used for chronic infection, tissue repair in vivo and serious wound healing. PDA complex has excellent mechanical properties and self-healing properties, and it is a stable material that can be used for a long period of time. Unlike other dressings, PDA complexes can achieve both photothermal therapy and electro activity. In this paper, wound healing is divided into four stages: antibacterial, anti-inflammatory, cell adhesion and proliferation, and re-epithelialization. Photothermal therapy can improve the bacteriostatic rate and remove reactive oxygen species to inhibit inflammation. Electrical signals can stimulate cell proliferation and directional migration. With low reactive oxygen species (ROS) levels, inflammatory factors are down-regulated and growth factors are up-regulated, forming regular collagen fibers and accelerating wound healing. Finally, five potential development directions are proposed, including increasing drug loading capacity, optimization of drug delivery platforms, improvement of photothermal conversion efficiency, intelligent electroactive materials and combined 3D printing.

A Polydopamine Nanoparticle-Knotted Poly(ethylene glycol) Hydrogel for On-Demand Drug Delivery and Chemo-photothermal Therapy

2017 ◽  
Vol 29 (3) ◽  
pp. 1370-1376 ◽  
Author(s):  
Xing Wang ◽  
Changping Wang ◽  
Xinyu Wang ◽  
Yitong Wang ◽  
Qiang Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Ethylene Glycol ◽  
Photothermal Therapy ◽  
Poly Ethylene Glycol ◽  
On Demand ◽  
Poly Ethylene

Degradation of high molar mass poly(ethylene glycol), poly(2-ethyl-2-oxazoline) and poly(vinyl pyrrolidone) by reactive oxygen species

2017 ◽  
Author(s):  
Robert Luxenhofer ◽  
Juliane Ulbricht ◽  
Moritz Faust
Keyword(s):  
Ethylene Glycol ◽  
Molar Mass ◽  
Gel Permeation Chromatography ◽  
Vinyl Pyrrolidone ◽  
Oxygen Species ◽  
Poly Ethylene Glycol ◽  
High Molar Mass ◽  
Poly Ethylene ◽  
Poly Vinyl Pyrrolidone ◽  
Apparent Molar Mass

The development of the apparent molar mass of different poly(ethylene glycol), poly(2-ethyl-2-oxazoline) and poly(vinyl pyrrolidone) upon incubation with hydrogen peroxide and different concentrations and catalytic amounts of CuSO4 was followed used gel permeation chromatography.

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