An oroxylin A-loaded aggregation-induced emission active polymeric system greatly increased the antitumor efficacy against squamous cell carcinoma

2020 ◽  
Vol 8 (10) ◽  
pp. 2040-2047
Author(s):  
Yejin Zhu ◽  
Yongjian Guo ◽  
Mengdi Liu ◽  
Libin Wei ◽  
Xiaotang Wang
Keyword(s):  
Drug Delivery ◽  
Squamous Cell Carcinoma ◽  
Cancer Therapy ◽  
Cell Carcinoma ◽  
Drug Delivery System ◽  
Delivery System ◽  
Squamous Cell ◽  
Active Drug ◽  
Polymeric System ◽  
Oroxylin A

A novel AIE-active drug delivery system was developed for imaging-guided cancer therapy with improved efficacy.

scholarly journals Evaluation of a New Hydroxyapatite Nanoparticle as a Drug Delivery System to Oral Squamous Cell Carcinoma Cells

2018 ◽  
Vol 38 (12) ◽  
pp. 6715-6720 ◽  
Author(s):  
TAKU MURATA ◽  
TOMOHIKO KUTSUNA ◽  
KAZUTO KUROHARA ◽  
KASUMI SHIMIZU ◽  
AKIRA TOMEOKU ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Drug Delivery System ◽  
Delivery System ◽  
Squamous Cell ◽  
Carcinoma Cells

Glutathione-sensitive and folate-targeted nanoparticles loaded with paclitaxel to enhance oral squamous cell carcinoma therapy

2020 ◽  
Vol 8 (15) ◽  
pp. 3113-3122 ◽  
Author(s):  
Lei Fan ◽  
Jianquan Wang ◽  
Chengwan Xia ◽  
Qian Zhang ◽  
Yumei Pu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Squamous Cell Carcinoma ◽  
Folic Acid ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Drug Delivery System ◽  
Delivery System ◽  
Squamous Cell ◽  
Targeted Nanoparticles

In this study, a drug delivery system based on glutathione (GSH)-sensitive and folic acid (FA)-targeted nanoparticles loaded with paclitaxel (FA-PEG-S-S-PCL@PTX, FA-NPs) was developed.

scholarly journals Local drug delivery system for the treatment of tongue squamous cell carcinoma in rats

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Mariam Kakabadze ◽  
Teona Paresishvili ◽  
Konstantine Mardaleishvili ◽  
Zurab Vadachkoria ◽  
Nicholas Kipshidze ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Drug Delivery System ◽  
Delivery System ◽  
Squamous Cell ◽  
Tongue Squamous Cell Carcinoma ◽  
Local Drug Delivery ◽  
Local Drug Delivery System

scholarly journals Milk-exosome based pH/light sensitive drug system to enhance anticancer activity against oral squamous cell carcinoma

RSC Advances ◽  
2020 ◽  
Vol 10 (47) ◽  
pp. 28314-28323 ◽  
Author(s):  
Qian Zhang ◽  
Qi Xiao ◽  
Honglin Yin ◽  
Chengwan Xia ◽  
Yumei Pu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Squamous Cell Carcinoma ◽  
Tumor Microenvironment ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Anticancer Activity ◽  
Drug Delivery System ◽  
Squamous Cell ◽  
Squamous Cell Carcinomas ◽  
Cancer Tissues

A multimodal drug delivery system targeting the tumor microenvironment is an inspiring method for treating cancer tissues, including oral squamous cell carcinomas (OSCC).

scholarly journals PEGylated ethyl cellulose micelles as a nanocarrier for drug delivery

RSC Advances ◽  
2021 ◽  
Vol 11 (49) ◽  
pp. 30532-30543
Author(s):  
Amarnath Singam ◽  
Naresh Killi ◽  
Pratikshkumar R. Patel ◽  
Rathna V. N. Gundloori
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Ethyl Cellulose ◽  
Amphiphilic Polymer ◽  
Polymeric System ◽  
Next Generation ◽  
Nano Drug Delivery

Ethyl cellulose was developed as an amphiphilic polymer by PEGylation and fabricated as nanomicelles for delivery of active molecules. This polymeric system can be used as next generation nano drug delivery system (nanoDDS) for cancer therapy.

scholarly journals Novel concept of the smart NIR-light–controlled drug release of black phosphorus nanostructure for cancer therapy

2018 ◽  
Vol 115 (3) ◽  
pp. 501-506 ◽  
Author(s):  
Meng Qiu ◽  
Dou Wang ◽  
Weiyuan Liang ◽  
Liping Liu ◽  
Yin Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Release ◽  
Drug Delivery System ◽  
Delivery System ◽  
Near Infrared ◽  
Black Phosphorus ◽  
Deep Penetration ◽  
Nir Light

A biodegradable drug delivery system (DDS) is one the most promising therapeutic strategies for cancer therapy. Here, we propose a unique concept of light activation of black phosphorus (BP) at hydrogel nanostructures for cancer therapy. A photosensitizer converts light into heat that softens and melts drug-loaded hydrogel-based nanostructures. Drug release rates can be accurately controlled by light intensity, exposure duration, BP concentration, and hydrogel composition. Owing to sufficiently deep penetration of near-infrared (NIR) light through tissues, our BP-based system shows high therapeutic efficacy for treatment of s.c. cancers. Importantly, our drug delivery system is completely harmless and degradable in vivo. Together, our work proposes a unique concept for precision cancer therapy by external light excitation to release cancer drugs. If these findings are successfully translated into the clinic, millions of patients with cancer will benefit from our work.

Functionalized halloysite nanotube by chitosan grafting for drug delivery of curcumin to achieve enhanced anticancer efficacy

2016 ◽  
Vol 4 (13) ◽  
pp. 2253-2263 ◽  
Author(s):  
Mingxian Liu ◽  
Yanzhou Chang ◽  
Jing Yang ◽  
Yuanyuan You ◽  
Rui He ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Halloysite Nanotube ◽  
Anticancer Efficacy

A new HNTs-based drug delivery system to improve the bioavailability of curcumin for cancer therapy is proposed.

Sign in / Sign up

Export Citation Format

Share Document