Ternary hydrogels with tunable mechanical and self-healing properties based on the synergistic effects of multiple dynamic  bonds

2020 ◽  
Vol 8 (21) ◽  
pp. 4660-4671 ◽  
Author(s):  
Kun Li ◽  
Jingxi Wang ◽  
Ping Li ◽  
Yubo Fan
Keyword(s):  
Mechanical Properties ◽  
Hydrogen Bonds ◽  
Synergistic Effects ◽  
Self Healing ◽  
Tunable Mechanical Properties

Ternary hydrogels with tunable mechanical properties were prepared based on the synergistic effects of hydrogen bonds and imine bonds.

scholarly journals A Robust, Tough and Multifunctional Polyurethane/Tannic Acid Hydrogel Fabricated by Physical-Chemical Dual Crosslinking

Polymers ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 239 ◽  
Author(s):  
Jie Wen ◽  
Xiaopeng Zhang ◽  
Mingwang Pan ◽  
Jinfeng Yuan ◽  
Zhanyu Jia ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tensile Strength ◽  
Polyethylene Glycol ◽  
Hydrogen Bonds ◽  
Tannic Acid ◽  
Hydroxyl Groups ◽  
Self Healing ◽  
Physical Chemical ◽  
Biomedical Field ◽  
Physical Crosslinking

Commonly synthetic polyethylene glycol polyurethane (PEG–PU) hydrogels possess poor mechanical properties, such as robustness and toughness, which limits their load-bearing application. Hence, it remains a challenge to prepare PEG–PU hydrogels with excellent mechanical properties. Herein, a novel double-crosslinked (DC) PEG–PU hydrogel was fabricated by combining chemical with physical crosslinking, where trimethylolpropane (TMP) was used as the first chemical crosslinker and polyphenol compound tannic acid (TA) was introduced into the single crosslinked PU network by simple immersion process. The second physical crosslinking was formed by numerous hydrogen bonds between urethane groups of PU and phenol hydroxyl groups in TA, which can endow PEG–PU hydrogel with good mechanical properties, self-recovery and a self-healing capability. The research results indicated that as little as a 30 mg·mL−1 TA solution enhanced the tensile strength and fracture energy of PEG–PU hydrogel from 0.27 to 2.2 MPa, 2.0 to 9.6 KJ·m−2, respectively. Moreover, the DC PEG–PU hydrogel possessed good adhesiveness to diverse substrates because of TA abundant catechol groups. This work shows a simple and versatile method to prepare a multifunctional DC single network PEG–PU hydrogel with excellent mechanical properties, and is expected to facilitate developments in the biomedical field.

Injectable Self-Healing Zwitterionic Hydrogels Based on Dynamic Benzoxaborole–Sugar Interactions with Tunable Mechanical Properties

2018 ◽  
Vol 19 (2) ◽  
pp. 596-605 ◽  
Author(s):  
Yangjun Chen ◽  
Wenda Wang ◽  
Di Wu ◽  
Masanori Nagao ◽  
Dennis G. Hall ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Self Healing ◽  
Tunable Mechanical Properties

Injectable and Self-Healing Dynamic Hydrogels Based on Metal(I)-Thiolate/Disulfide Exchange as Biomaterials with Tunable Mechanical Properties

2015 ◽  
Vol 16 (11) ◽  
pp. 3552-3561 ◽  
Author(s):  
Pablo Casuso ◽  
Ibon Odriozola ◽  
Adrián Pérez-San Vicente ◽  
Iraida Loinaz ◽  
Germán Cabañero ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Self Healing ◽  
Disulfide Exchange ◽  
Tunable Mechanical Properties

Self-healing quadruple-shape memory hydrogel based on imine, coordination, and borate bonds with tunable mechanical properties

2020 ◽  
Vol 298 (3) ◽  
pp. 285-291 ◽  
Author(s):  
Minying Wang ◽  
Baohang Mo ◽  
Birong Chen ◽  
Linbin Jiang ◽  
Hua Yang
Keyword(s):  
Mechanical Properties ◽  
Shape Memory ◽  
Self Healing ◽  
Tunable Mechanical Properties

An Injectable Interpenetrating Polymer Network Hydrogel with Tunable Mechanical Properties and Self-Healing Abilities

2017 ◽  
Vol 218 (23) ◽  
pp. 1700348 ◽  
Author(s):  
Yanan Wang ◽  
Hansen Yu ◽  
Haiyang Yang ◽  
Xiang Hao ◽  
Quan Tang ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Polymer Network ◽  
Interpenetrating Polymer Network ◽  
Self Healing ◽  
Tunable Mechanical Properties

A seawater‐assisted self‐healing metal–catechol polyurethane with tunable mechanical properties

2019 ◽  
Vol 68 (6) ◽  
pp. 1084-1090 ◽  
Author(s):  
Shaobin Xu ◽  
Dekun Sheng ◽  
Xiangdong Liu ◽  
Fance Ji ◽  
Yan Zhou ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Self Healing ◽  
Tunable Mechanical Properties

scholarly journals Bioinspired Histidine–Zn2+ Coordination for Tuning the Mechanical Properties of Self-Healing Coiled Coil Cross-Linked Hydrogels

Biomimetics ◽  
2019 ◽  
Vol 4 (1) ◽  
pp. 25 ◽  
Author(s):  
Isabell Tunn ◽  
Matthew J. Harrington ◽  
Kerstin G. Blank
Keyword(s):  
Mechanical Properties ◽  
Self Assembly ◽  
Ethylenediaminetetraacetic Acid ◽  
Coiled Coil ◽  
Higher Order ◽  
Metal Coordination ◽  
Cross Linking ◽  
Self Healing ◽  
Poly Ethylene ◽  
Tunable Mechanical Properties

Natural biopolymeric materials often possess properties superior to their individual components. In mussel byssus, reversible histidine (His)–metal coordination is a key feature, which mediates higher-order self-assembly as well as self-healing. The byssus structure, thus, serves as an excellent natural blueprint for the development of self-healing biomimetic materials with reversibly tunable mechanical properties. Inspired by byssal threads, we bioengineered His–metal coordination sites into a heterodimeric coiled coil (CC). These CC-forming peptides serve as a noncovalent cross-link for poly(ethylene glycol)-based hydrogels and participate in the formation of higher-order assemblies via intermolecular His–metal coordination as a second cross-linking mode. Raman and circular dichroism spectroscopy revealed the presence of α-helical, Zn2+ cross-linked aggregates. Using rheology, we demonstrate that the hydrogel is self-healing and that the addition of Zn2+ reversibly switches the hydrogel properties from viscoelastic to elastic. Importantly, using different Zn2+:His ratios allows for tuning the hydrogel relaxation time over nearly three orders of magnitude. This tunability is attributed to the progressive transformation of single CC cross-links into Zn2+ cross-linked aggregates; a process that is fully reversible upon addition of the metal chelator ethylenediaminetetraacetic acid. These findings reveal that His–metal coordination can be used as a versatile cross-linking mechanism for tuning the viscoelastic properties of biomimetic hydrogels.

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