Real-time imaging of alkaline phosphatase activity of diabetes in mice via a near-infrared fluorescent probe

2021 ◽  
Author(s):  
Wen-Xin Wang ◽  
Wen-Li Jiang ◽  
Hong Guo ◽  
Yongfei Li ◽  
Chun-Yan Li

A novel water-soluble near-infrared fluorescent probe named QX-P with simple synthesis is developed for detecting ALP. The probe can not only visualize ALP activity in four cell lines, but also real-time image ALP activity of diabetes in mice.

2019 ◽  
Vol 7 (3) ◽  
pp. 443-450 ◽  
Author(s):  
Qian Zhang ◽  
Shasha Li ◽  
Caixia Fu ◽  
Yuzhe Xiao ◽  
Peng Zhang ◽  
...  

A NIR ratiometric fluorescent probe based on cyanine dye was developed for detecting and intracellular imaging of ALP activity with high sensitivity.


Surgery ◽  
2011 ◽  
Vol 149 (5) ◽  
pp. 689-698 ◽  
Author(s):  
Yang Liu ◽  
Adam Q. Bauer ◽  
Walter J. Akers ◽  
Gail Sudlow ◽  
Kexian Liang ◽  
...  

The Analyst ◽  
2021 ◽  
Author(s):  
Xiao Pang ◽  
Yaqian Li ◽  
Qiujun Lu ◽  
Ziqi Ni ◽  
Zile Zhou ◽  
...  

Alkaline phosphatase (ALP) is an essential hydrolase and widely distributed in living organisms.


2017 ◽  
Vol 9 (8) ◽  
pp. 6796-6803 ◽  
Author(s):  
Yi Tan ◽  
Ling Zhang ◽  
Ka Ho Man ◽  
Raoul Peltier ◽  
Ganchao Chen ◽  
...  

1983 ◽  
Vol 130 (5) ◽  
pp. 149 ◽  
Author(s):  
D. Lavie ◽  
W.K. Taylor

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