In situ construction of a self-assembled AIE probe for tumor hypoxia imaging

Nanoscale ◽  
2020 ◽  
Vol 12 (14) ◽  
pp. 7509-7513 ◽  
Author(s):  
Tianhao Xue ◽  
Kuanchun Shao ◽  
Jingyuan Xiang ◽  
Xinyi Pan ◽  
Zixuan Zhu ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Self Assembly ◽  
Tumor Hypoxia ◽  
Water Soluble ◽  
Hypoxia Imaging ◽  
Self Assembled

A novel hypoxia-responsive fluorescent probe of a hydrophilic azobenzene containing copolymer combined with a carbamate linkage and anionic water-soluble tetraphenylethene by using the in situ self-assembly concept for tumor hypoxia imaging is reported.

scholarly journals First in situ vesicular self-assembly of ‘binols’ generated by a two-component aerobic oxidation reaction

RSC Advances ◽  
2018 ◽  
Vol 8 (51) ◽  
pp. 29155-29163 ◽  
Author(s):  
Braja G. Bag ◽  
Subrata Ghorai ◽  
Saikat K. Panja ◽  
Shaishab K. Dinda ◽  
Koushik Paul
Keyword(s):  
Self Assembly ◽  
Oxidation Reaction ◽  
Aerobic Oxidation ◽  
Alkyl Chains ◽  
Two Component ◽  
Donor Acceptor ◽  
Self Assembled ◽  
Naphthol Derivatives

Binol derivatives, obtained by aerobic coupling of two 2-naphthol derivatives having H-bond donor–acceptor groups and appended alkyl chains, spontaneously self-assembled in situ yielding vesicular self-assemblies and gels.

A turn-on fluorescent probe for tumor hypoxia imaging in living cells

2015 ◽  
Vol 51 (79) ◽  
pp. 14739-14741 ◽  
Author(s):  
Qi Cai ◽  
Tao Yu ◽  
Weiping Zhu ◽  
Yufang Xu ◽  
Xuhong Qian
Keyword(s):  
Fluorescent Probe ◽  
Hela Cells ◽  
Tumor Hypoxia ◽  
Living Cells ◽  
Hypoxia Imaging ◽  
Turn On ◽  
Reducing Ability ◽  
Oxygen Concentrations

A turn-on fluorescent probe was designed and synthesized for tumor hypoxia imaging, which could show excellent reducing ability under chemical or bio-reductase conditions and good performance in hypoxia imaging for HeLa cells at different oxygen concentrations.

In-Situ Visualization of Evaporation Induced Self-Assembly Phenomena of Nanofluids Detecting the Interfacial Surface Plasmon Reflectance

2015 ◽  
Author(s):  
Iltai (Isaac) Kim ◽  
Kenneth David Kihm
Keyword(s):  
Refractive Index ◽  
Real Time ◽  
Surface Plasmon ◽  
Self Assembly ◽  
Effective Refractive Index ◽  
In Situ Visualization ◽  
Evaporation Induced Self Assembly ◽  
Self Assembled ◽  
Mapping Techniques

Innovative optical techniques based on nano-biophotonics such as surface plasmon resonance (SPR) imaging and R-G-B natural fringe mapping techniques are developed to characterize the transport and optical properties of nanofluids in situ, real-time, and full field manner. Recent results regarding the characterization of nanofluids are summarized and future research directions are presented. 47 nm Al2O3 nanoparticles are dispersed in water with various concentrations. Al2O3 nanofluids droplets are placed on substrates and evaporated in room temperature. In-situ visualization of evaporation-induced self-assembly is conducted to detect concentration, effective refractive index, and different self-assembled pattern including cavity with various nanofluids concentrations and surface hydrophobbicities with SPR and fringe mapping. During the evaporation, time-dependent and near-field nanoparticle concentrations are determined by correlating the SPR reflectance intensities with the effective refractive index (ERI) of the nanofluids. With increasing the concentrations of nanofluids, the existence of hidden complex cavities inside a self-assembled nanocrystalline structure or final dryout pattern is discovered in real-time. R-G-B natural fringe mapping allowed the reconstruction of the 3D cavity formation and crystallization processes quantitatively. The formation of the complex inner structure was found to be attributable to multiple cavity inceptions and their competing growth during the aquatic evaporation. Furthermore, the effect of surface hydrophobicity is examined in the formation of hidden complex cavities, taking place on three different substrates bearing different levels of hydrophobicity; namely, cover glass (CG), gold thin film (Au), and polystyrene dish (PS). These surface plamson resonance imaging and natural fringe mapping techniques are expected to provide a breakthrough in micro-nanoscale thermal fluids phenomena and nano-biochemical sensing when coupled with localized surface Plasmon and metamaterials techniques.

scholarly journals An enzyme-free molecular catalytic device: dynamically self-assembled DNA dendrimers for in situ imaging of microRNAs in live cells

2019 ◽  
Vol 10 (6) ◽  
pp. 1651-1658 ◽  
Author(s):  
Shuzhen Yue ◽  
Xinyue Song ◽  
Weiling Song ◽  
Sai Bi
Keyword(s):  
Self Assembly ◽  
Signal Amplification ◽  
High Sensitivity ◽  
Live Cells ◽  
Sensitivity And Selectivity ◽  
Catalytic Hairpin Assembly ◽  
Self Assembled ◽  
In Situ Imaging

Branched catalytic hairpin assembly is proposed for dynamic self-assembly of DNA dendrimers for signal amplification and in situ imaging of microRNAs in live cells with high sensitivity and selectivity.

Biomembrane induced in situ self-assembly of peptide with enhanced antimicrobial activity

2020 ◽  
Vol 8 (7) ◽  
pp. 2031-2039 ◽  
Author(s):  
Zhiwei Shen ◽  
Zhen Guo ◽  
Limin Zhou ◽  
Yujiao Wang ◽  
Jinjin Zhang ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Self Assembly ◽  
Lipid Membrane ◽  
Self Assembled

FF8 self-assembled into nanofibers on the negatively charged lipid membrane and induced rupture of the membrane.

Core-functionalizable Nanoaggregates: Preparation via Polymerization-induced Self-assembly and Their Applications

2021 ◽  
Author(s):  
Panittha Damsongsang ◽  
Voravee Hoven ◽  
Shinichi Yusa
Keyword(s):  
Self Assembly ◽  
Self Assembled

The combination of polymerization-induced self-assembly (PISA) and post-polymerization modification is a versatile route by which to prepare core-functionalized nanoaggregates. PISA is a useful approach for preparing in situ self-assembled nano-objects...

Monitoring pattern formation in drying and wetting dispersions of gold nanoparticles by ESEM

2015 ◽  
Vol 181 ◽  
pp. 281-298 ◽  
Author(s):  
Casper Kunstmann-Olsen ◽  
Domagoj Belić ◽  
Mathias Brust
Keyword(s):  
Gold Nanoparticles ◽  
Self Assembly ◽  
Early Stage ◽  
Environmental Scanning Electron Microscopy ◽  
Water Soluble ◽  
Environmental Scanning ◽  
Evaporation And Condensation ◽  
Lift Off ◽  
Poly Ethylene

We report an investigation of the self-assembly of patterns from functionalized gold nanoparticles (GNPs) by monitoring the process in situ by environmental scanning electron microscopy (ESEM) during both evaporation and condensation of the dispersant. As this method limits the choice of dispersants to water, GNPs functionalized with hydrophilic thiol ligands, containing poly(ethylene)glycol (PEG) groups, were used on a variety of substrates including pre-patterned ones. Particular emphasis was given to early stage deposition of GNPs, as well as redispersion and lift-off upon condensation of water droplets. ESEM presents a unique opportunity of directly imaging such events in situ. It was found that attractive interactions between the substrate and the GNPs are often stronger than expected once the particles have been deposited. The role of nickel perchlorate as a highly water-soluble additive was studied. It was found that entropically driven deposition of particles and decoration of surface features was enhanced in its presence, as expected.

Water-induced self-assembly of mixed gelator system (ceramide and lecithin) for edible oil structuring

2019 ◽  
Vol 10 (7) ◽  
pp. 3923-3933 ◽  
Author(s):  
Shenglan Guo ◽  
Mingyue Song ◽  
Xiaoting He ◽  
Fuyu Yang ◽  
Yong Cao ◽  
...  
Keyword(s):  
Sunflower Oil ◽  
Self Assembly ◽  
Edible Oil ◽  
Water Soluble ◽  
Fat Replacers ◽  
Self Assembled

In the presence of a small amount of water, CER and LEC were self-assembled to form oleogels in sunflower oil. This can be used to produce hard-stock fat replacers as well as for incorporating water-soluble nutrients into oil-based products.

scholarly journals Face and edge directed self-assembly of Pd12 tetrahedral nano-cages and their self-sorting

2016 ◽  
Vol 7 (9) ◽  
pp. 5893-5899 ◽  
Author(s):  
Prodip Howlader ◽  
Partha Sarathi Mukherjee
Keyword(s):  
Self Assembly ◽  
Water Soluble ◽  
Self Assembled ◽  
Aromatic Nitro

A di-tetrazole ligand was used to occupy the edges of a tetrahedron to generate an edge-directed self-assembled Pd12 water soluble cage which was used as a vessel to encapsulate aromatic nitro-olefins. A face directed Pd12 tetrahedral cage was also constructed occupying the triangular faces of the tetrahedron by a tri-tetrazole ligand.

Sign in / Sign up

Export Citation Format

Share Document