A turn-on fluorescent probe for tumor hypoxia imaging in living cells

2015 ◽  
Vol 51 (79) ◽  
pp. 14739-14741 ◽  
Author(s):  
Qi Cai ◽  
Tao Yu ◽  
Weiping Zhu ◽  
Yufang Xu ◽  
Xuhong Qian
Keyword(s):  
Fluorescent Probe ◽  
Hela Cells ◽  
Tumor Hypoxia ◽  
Living Cells ◽  
Hypoxia Imaging ◽  
Turn On ◽  
Reducing Ability ◽  
Oxygen Concentrations

A turn-on fluorescent probe was designed and synthesized for tumor hypoxia imaging, which could show excellent reducing ability under chemical or bio-reductase conditions and good performance in hypoxia imaging for HeLa cells at different oxygen concentrations.

A turn-on fluorescent probe for real-time detection of endogenous cysteine in living cells

2020 ◽  
Vol 226 ◽  
pp. 117506
Author(s):  
Guomin Zhao ◽  
Wenge Yang ◽  
Fangzhao Li ◽  
Zhenmei Deng ◽  
Yonghong Hu
Keyword(s):  
Real Time ◽  
Fluorescent Probe ◽  
Living Cells ◽  
Turn On ◽  
Real Time Detection

Colorimetric and Fluorescent Probe for Hypochlorite with High Selectivity

2013 ◽  
Vol 295-298 ◽  
pp. 475-478 ◽  
Author(s):  
Zhi Xiang Han ◽  
Ming Hui Du ◽  
Guo Xi Liang ◽  
Xiang Yang Wu
Keyword(s):  
Reactive Oxygen Species ◽  
Aqueous Solution ◽  
Detection Limit ◽  
Fluorescent Probe ◽  
Rhodamine B ◽  
High Selectivity ◽  
Reactive Oxygen ◽  
Living Cells ◽  
Oxygen Species ◽  
Turn On

Rhodamine B thiohydrazide (RBS) was firstly employed as turn-on fluorescent probe for hypochlorite in aqueous solution and living cells. It exhibits a stable response to hypochlorite from 1.0×10-6to 1.0×10-5M with a detection limit of 3.3×10-7M. The response of this probe to hypochlorite is fast and highly selective compared with other reactive oxygen species (such as.OH,1O2, H2O2) and other common anions (such as X-, ClO2-, ClO4-, NO3-, NO2-, OH-, Ac-, CO32-, SO42-).

Near-infrared templated fluorescent probe for nitroxyl: Selective and sensitive turn-on detection in living cells

2020 ◽  
Vol 310 ◽  
pp. 127839 ◽  
Author(s):  
Sathyadevi Palanisamy ◽  
Li-Fong Chen ◽  
Shey-Cherng Tzou ◽  
Yun-Ming Wang
Keyword(s):  
Fluorescent Probe ◽  
Near Infrared ◽  
Living Cells ◽  
Turn On

A two-photon fluorescent probe for imaging of endogenous formaldehyde in HeLa cells and quantitative detection of basal formaldehyde in milk samples

2019 ◽  
Vol 11 (23) ◽  
pp. 2969-2975 ◽  
Author(s):  
Fangyun Xin ◽  
Yong Tian ◽  
Jing Jing ◽  
Xiaoling Zhang
Keyword(s):  
Fluorescent Probe ◽  
Hela Cells ◽  
Living Cells ◽  
Quantitative Detection ◽  
Two Photon ◽  
Milk Samples

A fluorescent probe NaP which can image endogenous formaldehyde in living cells and quantitatively detect basal formaldehyde in milk samples.

A turn-on Schiff base fluorescent probe for the exogenous and endogenous Fe3+ ion sensing and bioimaging of living cells

2020 ◽  
Vol 44 (45) ◽  
pp. 19642-19649
Author(s):  
Lingjie Hou ◽  
Tao Liu ◽  
Yaling Gong ◽  
Jin Li ◽  
Chenhua Deng ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Schiff Base ◽  
Fluorescent Probe ◽  
Living Cells ◽  
Naphthalic Anhydride ◽  
Turn On ◽  
Ion Sensing

A Schiff base fluorescent probe, namely naphthalic anhydride – (2-pyridine) hydrazone (NAH), has been synthesized and developed for the highly selective and sensitive monitoring of Fe3+ ions in an aqueous solution and living cells.

Rhodamine-based “turn-on” fluorescent probe with high selectivity for Fe2+ imaging in living cells

2013 ◽  
Vol 439 (4) ◽  
pp. 459-463 ◽  
Author(s):  
Gui-Ge Hou ◽  
Chun-Hua Wang ◽  
Ju-Feng Sun ◽  
Mei-Zi Yang ◽  
Dong Lin ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
High Selectivity ◽  
Living Cells ◽  
Turn On

A two-photon fluorescent probe for selective methylglyoxal detection and application in living cells

2015 ◽  
Vol 7 (6) ◽  
pp. 2386-2390 ◽  
Author(s):  
Tun Tang ◽  
Yimin Zhou ◽  
Yuqi Chen ◽  
Mengjun Li ◽  
Yan Feng ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Living Cells ◽  
Two Photon ◽  
Turn On

A novel two-photon fluorescent “turn-on” probe could detect methylglyoxal levels in living cells conveniently.

Estrogen receptor sensing in living cells by a high affinity turn-on fluorescent probe

2018 ◽  
Vol 272 ◽  
pp. 589-597 ◽  
Author(s):  
Lu Yang ◽  
Qiuyu Meng ◽  
Zhiye Hu ◽  
Wentao Ning ◽  
Jie Zheng ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Fluorescent Probe ◽  
Living Cells ◽  
High Affinity ◽  
Turn On

scholarly journals A Turn-On Fluorescent Probe for Sensitive Detection of Cysteine in a Fully Aqueous Environment and in Living Cells

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Xiaohua Ma ◽  
Guoguang Wu ◽  
Yuehua Zhao ◽  
Zibo Yuan ◽  
Yu Zhang ◽  
...  
Keyword(s):  
Detection Limit ◽  
Fluorescent Probe ◽  
High Selectivity ◽  
Coumarin Derivative ◽  
Living Cells ◽  
Sensitive Detection ◽  
Aqueous Environment ◽  
Test Probe ◽  
Aqueous Buffer ◽  
Turn On

We reported here a turn-on fluorescent probe (1) for the detection of cysteine (Cys) by incorporating the recognition unit of 2,4-dinitrobenzenesulfonyl ester (DNBS) to a coumarin derivative. The structure of the obtained probe was confirmed by NMR and HRMS techniques. The probe shows a remarkable fluorescence off-on response (∼52-fold) by the reaction with Cys in 100% aqueous buffer. The sensing mechanism was verified by the HPLC test. Probe 1 also displays high selectivity towards Cys. The detection limit was calculated to be 23 nM. Moreover, cellular experiments demonstrated that the probe is highly biocompatible and can be used for monitoring intracellular Cys.

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