A ratiometric photoacoustic imaging approach for semi-quantitative determination of aggregation efficiency in vivo

Nanoscale ◽  
2020 ◽  
Vol 12 (36) ◽  
pp. 18654-18662
Author(s):  
Bo Peng ◽  
Xiu-Mei Liu ◽  
Hsian-Rong Tseng ◽  
Li-Li Li ◽  
Hao Wang
Keyword(s):  
Quantitative Determination ◽  
Real Time ◽  
Pancreatic Tumor ◽  
Photoacoustic Imaging ◽  
High Contrast ◽  
Imaging Approach

We first proposed a ratiometric photoacoustic (PA) imaging approach for real-time semi-quantitative calculated aggregation efficiency in vivo. The designed probe with high contrast will used for pancreatic tumor bioimaging or operation navigation.

scholarly journals Real-time interleaved spectroscopic photoacoustic and ultrasound (PAUS) scanning with simultaneous fluence compensation and motion correction

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Geng-Shi Jeng ◽  
Meng-Lin Li ◽  
MinWoo Kim ◽  
Soon Joon Yoon ◽  
John J. Pitre ◽  
...  
Keyword(s):  
Real Time ◽  
Motion Correction ◽  
Photoacoustic Imaging ◽  
Tunable Laser ◽  
Large Area ◽  
Automatic Compensation ◽  
Imaging Approach ◽  
Time Interleaved ◽  
Time Systems

AbstractFor over two decades photoacoustic imaging has been tested clinically, but successful human trials have been limited. To enable quantitative clinical spectroscopy, the fundamental issues of wavelength-dependent fluence variations and inter-wavelength motion must be overcome. Here we propose a real-time, spectroscopic photoacoustic/ultrasound (PAUS) imaging approach using a compact, 1-kHz rate wavelength-tunable laser. Instead of illuminating tissue over a large area, the fiber-optic delivery system surrounding an US array sequentially scans a narrow laser beam, with partial PA image reconstruction for each laser pulse. The final image is then formed by coherently summing partial images. This scheme enables (i) automatic compensation for wavelength-dependent fluence variations in spectroscopic PA imaging and (ii) motion correction of spectroscopic PA frames using US speckle tracking in real-time systems. The 50-Hz video rate PAUS system is demonstrated in vivo using a murine model of labelled drug delivery.

Quantitative Determination of Fatty Acid Hydroperoxides in Vivo

1988 ◽  
pp. 175-178
Author(s):  
Hartmut Frank ◽  
Manfred Wiegand ◽  
Dietmar Thiel
Keyword(s):  
Fatty Acid ◽  
Quantitative Determination ◽  
Fatty Acid Hydroperoxides

scholarly journals A one-step method for quantitative determination of uracil in DNA by real-time PCR

2010 ◽  
Vol 38 (21) ◽  
pp. e196-e196 ◽  
Author(s):  
András Horváth ◽  
Beáta G. Vértessy
Keyword(s):  
Quantitative Determination ◽  
Real Time ◽  
Real Time Pcr ◽  
Step Method ◽  
One Step

Pegylated magnetic nanocarriers for doxorubicin delivery: A quantitative determination of stealthiness in vitro and in vivo

2012 ◽  
Vol 81 (3) ◽  
pp. 498-505 ◽  
Author(s):  
E. Allard-Vannier ◽  
S. Cohen-Jonathan ◽  
J. Gautier ◽  
K. Hervé-Aubert ◽  
E. Munnier ◽  
...  
Keyword(s):  
Quantitative Determination ◽  
Doxorubicin Delivery ◽  
Magnetic Nanocarriers

Real-time monitoring and accurate diagnosis of drug-induced hepatotoxicity in vivo by ratio-fluorescence and photoacoustic imaging of peroxynitrite

Nanoscale ◽  
2020 ◽  
Vol 12 (18) ◽  
pp. 10216-10225 ◽  
Author(s):  
Hongjun Zhuang ◽  
Benhao Li ◽  
Mengyao Zhao ◽  
Peng Wei ◽  
Wei Yuan ◽  
...  
Keyword(s):  
Real Time ◽  
Photoacoustic Imaging ◽  
Accurate Diagnosis ◽  
Cyanine Dye ◽  
Upconversion Nanoparticles ◽  
Real Time Monitoring ◽  
Drug Induced ◽  
Monitoring Drug

Cyanine dye-coordinated upconversion nanoparticles were developed for real-time monitoring drug-induced hepatotoxicity in vivo by ratio-fluorescence and photoacoustic imaging of peroxynitrite.

scholarly journals Applicability of a duplex and four singleplex real-time PCR assays for the qualitative and quantitative determination of wild boar and domestic pig meat in processed food products

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Maria Kaltenbrunner ◽  
Walter Mayer ◽  
Kirsten Kerkhoff ◽  
Rita Epp ◽  
Hermann Rüggeberg ◽  
...  
Keyword(s):  
Quantitative Determination ◽  
Wild Boar ◽  
Real Time ◽  
Real Time Pcr ◽  
Processed Food ◽  
Domestic Pig ◽  
The Real ◽  
Qualitative And Quantitative ◽  
Pcr Assays

Abstract Appropriate analytical methods are needed for the detection of food authentication. We investigated the applicability of a duplex real-time PCR assay targeting chromosome 1 and two singleplex real-time PCR assays targeting chromosome 9, both published recently, for the qualitative and quantitative determination of wild boar and domestic pig in processed food products. In addition, two singleplex real-time PCR assays targeting chromosome 7 were tested for their suitability to differentiate the two subspecies. Even by targeting the three genome loci, the probability of misclassification was not completely eliminated. Application of the real-time PCR assays to a total of 35 commercial meat products, including 22 goulash products, revealed that domestic pig DNA was frequently present, even in 14 out of 15 products declared to consist of 100% wild boar. Quantitative results obtained with the real-time PCR assays for wild boar (p < 0.001) and those for domestic pig (p < 0.001) were significantly different. However, the results obtained with the real-time PCR assays for wild boar (r = 0.673; p < 0.001) and those for domestic pig (r = 0.505; p = 0.002) were found to be significantly correlated. If the rules given in the paper are followed, the real-time PCR assays are applicable for routine analysis.

scholarly journals 603 Handheld dual-modality ultrasound and photoacoustic imaging for in vivo determination of melanoma depth

2016 ◽  
Vol 136 (5) ◽  
pp. S107
Author(s):  
S.V. Tripathi ◽  
Y. Zhou ◽  
G.P. Linette ◽  
I.S. Rosman ◽  
M. Council ◽  
...  
Keyword(s):  
Photoacoustic Imaging ◽  
Dual Modality

Quantitative determination of cyanobacteria in mixed phytoplankton assemblages by an in vivo fluorimetric method

1995 ◽  
Vol 302 (1) ◽  
pp. 81-87 ◽  
Author(s):  
Tsai-yun Lee ◽  
Mikio Tsuzuki ◽  
Toshifumi Takeuchi ◽  
Kenji Yokoyama ◽  
Isao Karube
Keyword(s):  
Quantitative Determination ◽  
Phytoplankton Assemblages ◽  
Fluorimetric Method

A real-time fluorescent sensor specific to Mg2+: crystallographic evidence, DFT calculation and its use for quantitative determination of magnesium in drinking water

2015 ◽  
Vol 44 (6) ◽  
pp. 2755-2762 ◽  
Author(s):  
Guangwen Men ◽  
Chunrong Chen ◽  
Shitong Zhang ◽  
Chunshuang Liang ◽  
Ying Wang ◽  
...  
Keyword(s):  
Drinking Water ◽  
Quantitative Determination ◽  
Real Time ◽  
Dft Calculation ◽  
Fluorescent Sensor ◽  
Turn On ◽  
Quantitative Monitoring ◽  
Fluorescence Turn On

An “off-the-shelf” fluorescence “turn-on” Mg2+ chemosensor BCSA has been developed for real-time quantitative monitoring of magnesium in drinking water.

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