Real-time monitoring and accurate diagnosis of drug-induced hepatotoxicity in vivo by ratio-fluorescence and photoacoustic imaging of peroxynitrite

Nanoscale ◽  
2020 ◽  
Vol 12 (18) ◽  
pp. 10216-10225 ◽  
Author(s):  
Hongjun Zhuang ◽  
Benhao Li ◽  
Mengyao Zhao ◽  
Peng Wei ◽  
Wei Yuan ◽  
...  
Keyword(s):  
Real Time ◽  
Photoacoustic Imaging ◽  
Accurate Diagnosis ◽  
Cyanine Dye ◽  
Upconversion Nanoparticles ◽  
Real Time Monitoring ◽  
Drug Induced ◽  
Monitoring Drug

Cyanine dye-coordinated upconversion nanoparticles were developed for real-time monitoring drug-induced hepatotoxicity in vivo by ratio-fluorescence and photoacoustic imaging of peroxynitrite.

scholarly journals Stimuli-Responsive Nanotheranostics for Real-Time Monitoring Drug Release by Photoacoustic Imaging

Theranostics ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 526-536 ◽  
Author(s):  
Zhen Yang ◽  
Jibin Song ◽  
Wei Tang ◽  
Wenpei Fan ◽  
Yunlu Dai ◽  
...  
Keyword(s):  
Drug Release ◽  
Real Time ◽  
Photoacoustic Imaging ◽  
Stimuli Responsive ◽  
Real Time Monitoring ◽  
Monitoring Drug

Real-time monitoring of circulating tumor cell release during tumor manipulation using in vivo photoacoustic and fluorescent flow cytometry

Head & Neck ◽  
2013 ◽  
Vol 36 (8) ◽  
pp. 1207-1215 ◽  
Author(s):  
Mazen A. Juratli ◽  
Mustafa Sarimollaoglu ◽  
Eric R. Siegel ◽  
Dmitry A. Nedosekin ◽  
Ekaterina I. Galanzha ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Tumor Cell ◽  
Real Time ◽  
Circulating Tumor Cell ◽  
Real Time Monitoring ◽  
Cell Release

Facile solvothermal synthesis of ultrathin spinel ZnMn2O4 nanospheres: An efficient electrocatalyst for in vivo and in vitro real time monitoring of H2O2

2021 ◽  
Vol 900 ◽  
pp. 115674
Author(s):  
Muthaiah Annalakshmi ◽  
Sakthivel Kumaravel ◽  
T.S.T. Balamurugan ◽  
Shen-Ming Chen ◽  
Ju-Liang He
Keyword(s):  
Real Time ◽  
Solvothermal Synthesis ◽  
Real Time Monitoring

Oxygen-Independent Real-Time Monitoring of Distinct Biphasic Glutamate Release Using Dialysis Electrode in Rat Striatum During Anoxia: In Vivo Evaluation of Glutamate Release and Reversed Uptake

2000 ◽  
Vol 17 (11) ◽  
pp. 1105-1114 ◽  
Author(s):  
SATOSHI ASAI ◽  
TADASHI KOHNO ◽  
YOICHI KATAYAMA ◽  
YUJI IRIBE ◽  
ISABUROU HOSOI ◽  
...  
Keyword(s):  
Real Time ◽  
Glutamate Release ◽  
Rat Striatum ◽  
Real Time Monitoring ◽  
In Vivo Evaluation

scholarly journals Non-invasive, real-time reporting drug release in vitro and in vivo

2015 ◽  
Vol 51 (32) ◽  
pp. 6948-6951 ◽  
Author(s):  
Yanfeng Zhang ◽  
Qian Yin ◽  
Jonathan Yen ◽  
Joanne Li ◽  
Hanze Ying ◽  
...  
Keyword(s):  
Drug Release ◽  
Real Time ◽  
Near Infrared ◽  
Reporting System ◽  
Real Time Monitoring ◽  
Near Infrared Fluorescence ◽  
Non Invasive ◽  
Fluorescence Dye

Anin vitroandin vivodrug-reporting system is developed for real-time monitoring of drug release via the analysis of the concurrently released near-infrared fluorescence dye.

Real-time in vivo bioluminescence imaging of drug-induced oxidative stress

2016 ◽  
Vol 258 ◽  
pp. S234
Author(s):  
S. Seyed Forootan ◽  
F. Mutter ◽  
J. Clarke ◽  
A. Kipar ◽  
K. Park ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Real Time ◽  
Bioluminescence Imaging ◽  
Drug Induced ◽  
In Vivo Bioluminescence Imaging

scholarly journals Orbitofrontal-striatal potentiation underlies stimulant induced hyperactivity

2019 ◽  
Author(s):  
Sebastiano Bariselli ◽  
Nanami Miyazaki ◽  
Alexxai Kravitz
Keyword(s):  
Real Time ◽  
High Frequency ◽  
High Frequency Stimulation ◽  
Locomotor Sensitization ◽  
Real Time Monitoring ◽  
Frequency Stimulation ◽  
Brain Pathways ◽  
Dorsomedial Striatum ◽  
Stimulation Of

AbstractStimulants are one of the most widely prescribed classes of pharmaceuticals, but it is unclear which brain pathways underlie their therapeutic and adverse actions. Here, with real-time monitoring of circuit plasticity, we demonstrate that psychostimulants strengthen orbitofrontal (OFC) to dorsomedial striatum (DMS) pathway synapses, and increase striatal output in awake mice. In vivo high-frequency stimulation of OFC-DMS pathway blocked stimulant-induced potentiation and the expression of locomotor sensitization, thereby directly linking OFC-DMS plasticity to hyperactivity.

scholarly journals A beacon in the cytoplasm: Tracking translation of single mRNAs

2016 ◽  
Vol 214 (6) ◽  
pp. 649-652 ◽  
Author(s):  
Hema V. Pingali ◽  
Angela K. Hilliker
Keyword(s):  
Real Time ◽  
New Technique ◽  
Real Time Monitoring ◽  
Protein Levels ◽  
Cell Biol ◽  
A New Technique ◽  
Control Protein

Translation is carefully regulated to control protein levels and allow quick responses to changes in the environment. Certain questions about translation in vivo have been unattainable until now. In this issue, Pichon et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201605024) describe a new technique to allow real-time monitoring of translation on single mRNAs.

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