Helical polymer self-assembly and chiral nanostructure formation

2021 ◽  
Vol 12 (13) ◽  
pp. 1857-1897
Author(s):  
Randall A. Scanga ◽  
James F. Reuther

This review surveys recent progress towards robust chiral nanostructure fabrication techniques using synthetic helical polymers, the unique inferred properties that these materials possess, and their intricate connection to natural, biological chirality.

RSC Advances ◽  
2016 ◽  
Vol 6 (64) ◽  
pp. 59066-59072 ◽  
Author(s):  
Biao Zhao ◽  
Jianping Deng

Micelles provide microenvironment effects for asymmetric polymerization: an unprecedented methodology for controlling the preferential helicity of synthetic helical polymers.


Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3310
Author(s):  
Shengda Liu ◽  
Jiayun Xu ◽  
Xiumei Li ◽  
Tengfei Yan ◽  
Shuangjiang Yu ◽  
...  

In the past few decades, enormous efforts have been made to synthesize covalent polymer nano/microstructured materials with specific morphologies, due to the relationship between their structures and functions. Up to now, the formation of most of these structures often requires either templates or preorganization in order to construct a specific structure before, and then the subsequent removal of previous templates to form a desired structure, on account of the lack of “self-error-correcting” properties of reversible interactions in polymers. The above processes are time-consuming and tedious. A template-free, self-assembled strategy as a “bottom-up” route to fabricate well-defined nano/microstructures remains a challenge. Herein, we introduce the recent progress in template-free, self-assembled nano/microstructures formed by covalent two-dimensional (2D) polymers, such as polymer capsules, polymer films, polymer tubes and polymer rings.


2020 ◽  
Vol 63 (8) ◽  
pp. 1418-1437 ◽  
Author(s):  
Jing Liu ◽  
Xingang Zhang ◽  
Wenqing Li ◽  
Changzhong Jiang ◽  
Ziyu Wang ◽  
...  

Author(s):  
Zhen Luo ◽  
Yujuan Gao ◽  
Zhongyu Duan ◽  
Yu Yi ◽  
Hao Wang

Mitochondria are well known to serve as the powerhouse for cells and also the initiator for some vital signaling pathways. A variety of diseases are discovered to be associated with the abnormalities of mitochondria, including cancers. Thus, targeting mitochondria and their metabolisms are recognized to be promising for cancer therapy. In recent years, great efforts have been devoted to developing mitochondria-targeted pharmaceuticals, including small molecular drugs, peptides, proteins, and genes, with several molecular drugs and peptides enrolled in clinical trials. Along with the advances of nanotechnology, self-assembled peptide-nanomaterials that integrate the biomarker-targeting, stimuli-response, self-assembly, and therapeutic effect, have been attracted increasing interest in the fields of biotechnology and nanomedicine. Particularly, in situ mitochondria-targeted self-assembling peptides that can assemble on the surface or inside mitochondria have opened another dimension for the mitochondria-targeted cancer therapy. Here, we highlight the recent progress of mitochondria-targeted peptide-nanomaterials, especially those in situ self-assembly systems in mitochondria, and their applications in cancer treatments.


2020 ◽  
Vol 56 (60) ◽  
pp. 8342-8354
Author(s):  
Shuying Yang ◽  
Lingxiang Jiang

This article summarizes recent progress on biomimetic subcellular structures and discusses integration of these isolated systems.


2019 ◽  
Vol 14 (24) ◽  
pp. 4741-4747 ◽  
Author(s):  
Ranajit Barman ◽  
Pradip Dey ◽  
Tathagata Mondal ◽  
Suhrit Ghosh

2020 ◽  
Vol 11 (31) ◽  
pp. 8224-8230 ◽  
Author(s):  
Jupen Liu ◽  
Zhonglong Luo ◽  
Le Yu ◽  
Ping Zhang ◽  
Hongqiu Wei ◽  
...  

Passerini multicomponent polymerization-induced assembly is reported to design a water-soluble, AIE-active, double-helical polymer with reversible multi-responsiveness to external stimuli and rapid visible-light degradability.


2016 ◽  
Vol 73 (2) ◽  
pp. 175-182
Author(s):  
Shin-nosuke NISHIMURA ◽  
Tomoyuki KOGA ◽  
Nobuyuki HIGASHI

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