scholarly journals The antioxidant potential of peptides obtained from the spotted babylon snail (Babylonia areolata) in treating human colon adenocarcinoma (Caco-2) cells

RSC Advances ◽  
2020 ◽  
Vol 10 (43) ◽  
pp. 25746-25757 ◽  
Author(s):  
Putcha Petsantad ◽  
Papassara Sangtanoo ◽  
Piroonporn Srimongkol ◽  
Tanatorn Saisavoey ◽  
Onrapak Reamtong ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Cell Line ◽  
Synthetic Peptides ◽  
Colon Adenocarcinoma ◽  
Human Colon ◽  
Antioxidant Peptides ◽  
Babylonia Areolata ◽  
Dose Dependent ◽  
Human Colon Adenocarcinoma ◽  
Subsequent Identification

The isolation and subsequent identification of the two novel antioxidant peptides, HTYHEVTKH, and WPVLAYHF from the spotted babylon snail was achieved. In the Caco-2 cell line, two synthetic peptides produced a dose-dependent response on antioxidant activity.

scholarly journals Antiproliferative Activity on Human Colon Adenocarcinoma Cells and In Vitro Antioxidant Effect of Anthocyanin-Rich Extracts from Peels of Species of the Myrtaceae Family

Molecules ◽  
2021 ◽  
Vol 26 (3) ◽  
pp. 564
Author(s):  
Nayara Simas Frauches ◽  
Júlia Montenegro ◽  
Thuane Amaral ◽  
Joel Pimentel Abreu ◽  
Gabriela Laiber ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Compounds ◽  
Colon Adenocarcinoma ◽  
Human Colon ◽  
Native Plant ◽  
Total Anthocyanin ◽  
Adenocarcinoma Cells ◽  
Human Colon Adenocarcinoma ◽  
Colon Adenocarcinoma Cells

There is a significant indication of the beneficial health effects of fruit rich diets. Fruits of native plant species have noticeably different phytochemicals and bioactive effects. The aim of this work was to characterize and compare the constituents of jabuticaba (Myrciaria jaboticaba, MJ), jamun-berry (Syzygium cumini, SC), and malay-apple (Syzygium malaccense, SM) extracts and their influence on antioxidant activity in vitro and antiproliferative effects on human colon adenocarcinoma cells. According to the results, dried peel powders (DP) have a high anthocyanin content, phenolic compounds, and antioxidant activity when compared to freeze dried extracts (FD). M. jaboticaba dried peel powder extract had a higher total anthocyanin and phenolic compounds content (802.90 ± 1.93 and 2152.92 ± 43.95 mg/100 g, respectively). A reduction in cell viability of HT-29 cells after treatment with M. jaboticaba extracts (DP-MJ and FD-MJ) was observed via MTT assay. Flow cytometry showed that the treatment with the anthocyanin-rich extracts from MJ, SC, and SM had an inhibitory impact on cell development due to G2/M arrest and caused a rise in apoptotic cells in relation to the control group. The findings of this study highlight the potential of peel powders from Myrtaceae fruits as an important source of natural antioxidants and a protective effect against colon adenocarcinoma.

Stable differentiation of a human colon adenocarcinoma cell line by sodium butyrate is associated with multidrug resistance

1994 ◽  
Vol 160 (2) ◽  
pp. 213-226 ◽  
Author(s):  
Samuel B. Ho ◽  
Pei-Sha Yan ◽  
Rajvir Dahiya ◽  
Brent A. Neuschwander-Tetri ◽  
Carol Basbaum ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Cell Line ◽  
Sodium Butyrate ◽  
Colon Adenocarcinoma ◽  
Human Colon ◽  
Adenocarcinoma Cell Line ◽  
Adenocarcinoma Cell ◽  
Human Colon Adenocarcinoma

Ellagitannins from Rubus idaeus L. Exert Geno- and Cytotoxic Effects against Human Colon Adenocarcinoma Cell Line Caco-2

2017 ◽  
Vol 65 (14) ◽  
pp. 2947-2955 ◽  
Author(s):  
Adriana Nowak ◽  
Michał Sójka ◽  
Elżbieta Klewicka ◽  
Lidia Lipińska ◽  
Robert Klewicki ◽  
...  
Keyword(s):  
Cell Line ◽  
Colon Adenocarcinoma ◽  
Human Colon ◽  
Rubus Idaeus ◽  
Adenocarcinoma Cell Line ◽  
Cytotoxic Effects ◽  
Adenocarcinoma Cell ◽  
Human Colon Adenocarcinoma

scholarly journals PXR-mediated induction of P-glycoprotein by anticancer drugs in a human colon adenocarcinoma-derived cell line

2009 ◽  
Vol 66 (4) ◽  
pp. 765-771 ◽  
Author(s):  
Stefan Harmsen ◽  
I. Meijerman ◽  
C. L. Febus ◽  
R. F. Maas-Bakker ◽  
J. H. Beijnen ◽  
...  
Keyword(s):  
Cell Line ◽  
Anticancer Drugs ◽  
Colon Adenocarcinoma ◽  
Human Colon ◽  
P Glycoprotein ◽  
Human Colon Adenocarcinoma

Establishment and Characterization of a Cell Line Derived from Human Colon Adenocarcinoma (HuCCL-14)

Pathobiology ◽  
1978 ◽  
Vol 46 (4) ◽  
pp. 220-230 ◽  
Author(s):  
A. Yaniv ◽  
Z. Altboum ◽  
A. Gazit ◽  
N. Bloch-Shtacher ◽  
E. Eylan
Keyword(s):  
Cell Line ◽  
Colon Adenocarcinoma ◽  
Human Colon ◽  
A Cell ◽  
Human Colon Adenocarcinoma
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