Controllable enzymatic superactivity of α-chymotrypsin activated by the electrostatic interaction with cationic gemini surfactants

Cationic Gemini surfactant concentration, the inorganic salts added and the pH value of surface tension obtained cationic gemini surfactant critical micelle concentration is 0.4mmol / L;by adding three kinds of inorganic salts NaCl, MgCl2, and Na2SO4 ,which Na2SO4 has the greatest impact on surface tension, followed by MgCl2.The surface minimum tension of the pH ranged from 9 to 11 , indicating that the surface activity of cationic gemini surfactants achieved the highest.

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Surface Activity Research of Cationic Gemini Surfactants

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.652-654.1450 ◽

2013 ◽

Vol 652-654 ◽

pp. 1450-1454

Author(s):

Zhen Zhong Fan ◽

Lan Lan Li ◽

Li Feng Zhang ◽

Qing Wang Liu

Keyword(s):

Surface Tension ◽

Critical Micelle Concentration ◽

Surface Activity ◽

Surfactant Concentration ◽

Gemini Surfactant ◽

Gemini Surfactants ◽

Ph Value ◽

Inorganic Salts ◽

Cationic Gemini Surfactant ◽

Cationic Gemini Surfactants

Cationic Gemini surfactant concentration, the inorganic salts added and the pH value of surface tension obtained cationic gemini surfactant critical micelle concentration is 0.4mmol / L;by adding three kinds of inorganic salts NaCl, MgCl2, and Na2SO4 ,which Na2SO4 has the greatest impact on surface tension, followed by MgCl2.The surface minimum tension of the pH ranged from 9 to 11 , indicating that the surface activity of cationic gemini surfactants achieved the highest.

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Surface tension study of cationic gemini surfactants binding to DNA

Open Chemistry ◽

10.2478/s11532-014-0513-7 ◽

2014 ◽

Vol 12 (5) ◽

pp. 577-585 ◽

Cited By ~ 9

Author(s):

Martin Pisárčik ◽

Ferdinand Devínsky

Keyword(s):

Gemini Surfactant ◽

Gemini Surfactants ◽

Adsorption Behaviour ◽

Binding Properties ◽

Simple Method ◽

Spacer Length ◽

Cationic Gemini Surfactants ◽

Methylene Groups ◽

Weak Adsorption ◽

Surface Tension Study

AbstractBinding of cationic gemini surfactants alkanediyl-a-ω-bis(dimethyldodecylammonium bromides) with variable polymethylene spacer length ranging from 2 to 12 methylene groups to DNA in NaBr solution is investigated utilizing the tensiometry method. A simple method is presented for calculating the number of surfactant molecules bound to DNA. The results are evaluated in terms of the gemini surfactant spacer length, showing that gemini molecules with either short spacers (2 methylene groups) or long spacers are most efficiently adsorbed to DNA. A weak adsorption to DNA was found for gemini molecules with a medium spacer length (6 methylene groups in the spacer). The binding properties of cationic gemini surfactants as a function of spacer length are consistent with the results obtained by other experimental methods (dynamic light scattering measurements, fluorescence spectroscopy), indicating identical adsorption behaviour of gemini molecules as a function of the spacer length.

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Synthesis and assessment of new cationic gemini surfactants as inhibitors for carbon steel corrosion in oilfield water

RSC Advances ◽

10.1039/c7ra07176k ◽

2017 ◽

Vol 7 (75) ◽

pp. 47335-47352 ◽

Cited By ~ 19

Author(s):

F. El-Taib Heakal ◽

M. A. Deyab ◽

M. M. Osman ◽

M. I. Nessim ◽

A. E. Elkholy

Keyword(s):

Carbon Steel ◽

Gemini Surfactant ◽

Gemini Surfactants ◽

Steel Corrosion ◽

Surfactant Molecule ◽

Cationic Gemini Surfactants ◽

Oilfield Water

Stylized representation of Gemini surfactant molecule.

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Self-assembly of cationic gemini surfactants, alkanediyl-bis-(dimethyldodecyl-ammonium bromide), in cyclohexane: effects of spacer length on their association into reverse lyotropic liquid crystalline or reverse vesicles

Soft Matter ◽

10.1039/c7sm02333b ◽

2018 ◽

Vol 14 (5) ◽

pp. 734-741 ◽

Cited By ~ 4

Author(s):

Shenglu Deng ◽

Jianxi Zhao

Keyword(s):

Self Assembly ◽

Liquid Crystalline ◽

Gemini Surfactant ◽

Gemini Surfactants ◽

Ammonium Bromide ◽

Spacer Length ◽

Cationic Gemini Surfactants ◽

Reverse Vesicles

An increase in the spacer length of the gemini surfactant 12-s-12 strongly influenced the aggregation of the surfactant in cyclohexane.

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Development of Lyophilized Gemini Surfactant-Based Gene Delivery Systems: Influence of Lyophilization on the Structure, Activity and Stability of the Lipoplexes

Journal of Pharmacy & Pharmaceutical Sciences ◽

10.18433/j3x60d ◽

2012 ◽

Vol 15 (4) ◽

pp. 548 ◽

Cited By ~ 13

Author(s):

Waleed Mohammed-Saeid ◽

Deborah Michel ◽

Anas El-Aneed ◽

Ronald E Verrall ◽

Nicholas H Low ◽

...

Keyword(s):

Conformational Changes ◽

Gemini Surfactant ◽

Gemini Surfactants ◽

Transfection Efficiency ◽

Gene Transfection ◽

Physiochemical Properties ◽

Cationic Gemini Surfactants ◽

The Stability ◽

In Vitro Transfection

Purpose. Cationic gemini surfactants have been studied as non-viral vectors for gene therapy. Clinical applications of cationic lipid/DNA lipoplexes are restricted by their instability in aqueous formulations. In this work, we investigated the influence of lyophilization on the essential physiochemical properties and in vitro transfection of gemini surfactant-lipoplexes. Additionally, we evaluated the feasibility of lyophilization as a technique for preparing lipoplexes with long term stability. Methods. A gemini surfactant [12-7NH-12] and plasmid DNA encoding for interferon-γ were used to prepare gemini surfactant/pDNA [P/G] lipoplexes. Helper lipid DOPE [L] was incorporated in all formulation producing a [P/G/L] system. Sucrose and trehalose were utilized as stabilizing agents. To evaluate the ability of lyophilization to improve the stability of gemini surfactant-based lipoplexes, four lyophilized formulations were stored at 25˚C for three months. The formulations were analyzed at different time-points for physiochemical properties and in vitro transfection. Results. The results showed that both sucrose and trehalose provided anticipated stabilizing effect. The transfection efficiency of the lipoplexes increased 2-3 fold compared to fresh formulations upon lyophilization. This effect can be attributed to the improvement of DNA compaction and changes in the lipoplex morphology due to the lyophilization/rehydration cycles. The physiochemical properties of the lyophilized formulations were maintained throughout the stability study. All lyophilized formulations showed a significant loss of gene transfection activity after three months of storage. Nevertheless, no significant losses of transfection efficiency were observed for three formulations after two months storage at 25 ˚C. Conclusion. Lyophilization significantly improved the physical stability of gemini surfactant-based lipoplexes compared to liquid formulations. As well, lyophilization improved the transfection efficiency of the lipoplexes. The loss of transfection activity upon storage is most probably due to the conformational changes in the supramolecular structure of the lipoplexes as a function of time and temperature rather than to DNA degradation. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.

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Surface Charge Density Determines the Efficiency of Cationic Gemini Surfactant Based Lipofection

Biophysical Journal ◽

10.1016/s0006-3495(03)74878-4 ◽

2003 ◽

Vol 84 (1) ◽

pp. 578-587 ◽

Cited By ~ 36

Author(s):

Samppa J. Ryhänen ◽

Matti J. Säily ◽

Tommi Paukku ◽

Stefano Borocci ◽

Giovanna Mancini ◽

...

Keyword(s):

Charge Density ◽

Surface Charge ◽

Surface Charge Density ◽

Gemini Surfactant ◽

Cationic Gemini Surfactant

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Inhibitory influence of cationic Gemini surfactant on the dissolution rate of N80 carbon steel in 15% HCl solution

Scientific Reports ◽

10.1038/s41598-021-90031-x ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

M. A. Deyab ◽

Q. Mohsen

Keyword(s):

Gemini Surfactant ◽

Gemini Surfactants ◽

Physical Adsorption ◽

Significant Risk ◽

Steel Pipe ◽

Inhibitory Influence ◽

Corrosion Properties ◽

Cationic Gemini Surfactant ◽

Significant Performance ◽

Petroleum Wells

AbstractStrong acids are commonly used in petroleum wells to remove scale layers from the surface of N80 C-steel pipe. The corrosive effects of these acids, on the other hand, pose a significant risk to C-steel pipes. For the first time, we discovered the anti-corrosion properties of cationic Gemini surfactant, 1,2-bis(dodecyldimethylammonio) ethane dibromide (DMAEB), for N80 C-steel pipe in acid washing solution (15.0% HCl). The DMAEB, in particular, can reduce the corrosion rate of N80 C-steel by approximately 97%. DMAEB molecules work as a mixed-type corrosion inhibitor, according to electrochemical results. The DMAEB demonstrated a high inhibition effect at high temperatures, as well as high activation energy against the corrosion process. DMAEB's significant performance is primarily due to physical adsorption on the N80 C-steel surface, as confirmed by adsorption isotherms, SEM, EDX, FT-IR, and theoretical studies. Our findings shed new light on the use of Gemini surfactants as corrosion inhibitors in petroleum wells.

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Sulfidogenic-corrosion inhibitory effect of cationic monomeric and gemini surfactants: planktonic and sessile diversity

RSC Advances ◽

10.1039/c6ra02393b ◽

2016 ◽

Vol 6 (48) ◽

pp. 42263-42278 ◽

Cited By ~ 9

Author(s):

A. Labena ◽

M. A. Hegazy ◽

H. Horn ◽

E. Müller

Keyword(s):

Metal Surface ◽

Gemini Surfactant ◽

Gemini Surfactants ◽

Inhibitory Effect ◽

Bulk Phase ◽

Cationic Gemini Surfactant

A cationic monomeric surfactant (CMS) and a cationic gemini surfactant (CGS) were successfully synthesized and characterized. Both surfactants prevent sulfidogenic activity in bulk phase and on metal surface (biofilms) at a salinity of 3.18% NaCl.

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A Fluorescence Study on Surface Properties of Cationic Gemini Surfactant with Some Special Alcohols

Borneo Journal of Resource Science and Technology ◽

10.33736/bjrst.2736.2020 ◽

2020 ◽

Vol 10 (2) ◽

pp. 126-130

Author(s):

Riyaj Mohammad

Keyword(s):

Surface Properties ◽

Gemini Surfactant ◽

Gemini Surfactants ◽

Aggregation Number ◽

Fluorescence Emission ◽

Mixed System ◽

Fluorescence Emission Spectrum ◽

Cationic Gemini Surfactant ◽

Pyrene Fluorescence ◽

Coating Agents

Alcohols are very important additives and played a measure role as co-surfactants in various industrial and research applications. While, Gemini surfactants are mainly used as effective emulsifiers, antifoaming agents, bactericidal agents, coating agents and corrosion inhibitors etc. Therefore, it is important to study about the variations in alkanol concentrations which affects the aggregation number and other related parameters. Surface properties of gemini surfactant butanediyl-1,4-bis(dimethyldodecylammonium bromide) (12-4-12) has been studied by using fluorescence method. This method has been used to calculate the aggregation number (Nagg) and the other related parameters like dielectric constant (D), Stern Volmer binding constant (KSV) of mixed system. This method is also very important for the calculation of the micropolarity of the mixed system (gemini/alcohol). The micropolarity has been obtained with the help of the ratio of intensity of peaks (I1/I3) of the pyrene fluorescence emission spectrum. Cetylpridinium chloride and pyrene were used as quencher and probe, respectively. Keywords: Gemini surfactant, special alcohols, aggregation number, micropolarity

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