Targeted delivery and controlled release of doxorubicin to cancer cells by smart ATP-responsive Y-shaped DNA structure-capped mesoporous silica nanoparticles

2021 ◽  
Vol 9 (5) ◽  
pp. 1351-1363 ◽  
Author(s):  
Elnaz Bagheri ◽  
Mona Alibolandi ◽  
Khalil Abnous ◽  
Seyed Mohammad Taghdisi ◽  
Mohammad Ramezani
Keyword(s):  
Controlled Release ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Cancer Cells ◽  
Delivery System ◽  
Targeted Delivery ◽  
Mesoporous Silica Nanoparticles ◽  
Dna Structure ◽  
Targeted Delivery System

In this study, a dual-receptor doxorubicin-targeted delivery system based on mesoporous silica nanoparticles (MSNs) modified with mucine-1 and ATP aptamers (DOX@MSNs-Apts) was developed.

Multifunctional dual-mesoporous silica nanoparticles loaded with a protein and dual antitumor drugs as a targeted delivery system

2019 ◽  
Vol 43 (44) ◽  
pp. 17284-17297 ◽  
Author(s):  
Fangxiang Song ◽  
Yan Li ◽  
Shuai Wang ◽  
Li Zhang ◽  
QianLin Chen
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Delivery System ◽  
Targeted Delivery ◽  
Mesoporous Silica Nanoparticles ◽  
Mesoporous Structure ◽  
Antitumor Drugs ◽  
Carboxyl Groups ◽  
System P ◽  
Targeted Delivery System

Herein, dual-mesoporous structure silica (with pore sizes from 2 to 4 nm and from 4 to 16 nm) simultaneously modified with amino and carboxyl groups was successfully synthesized.

scholarly journals Targeted delivery of mesoporous silica nanoparticles loaded monastrol into cancer cells: an in vitro study

2017 ◽  
Vol 7 (8) ◽  
pp. 549-555 ◽  
Author(s):  
Huzaifa Hanif ◽  
Samina Nazir ◽  
Kehkashan Mazhar ◽  
Muhammad Waseem ◽  
Shazia Bano ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Cancer Cells ◽  
Targeted Delivery ◽  
Mesoporous Silica Nanoparticles ◽  
In Vitro Study ◽  
Vitro Study

pH sensitive chitosan-mesoporous silica nanoparticles for targeted delivery of a ruthenium complex with enhanced anticancer effects

2016 ◽  
Vol 45 (45) ◽  
pp. 18147-18155 ◽  
Author(s):  
Gaochao Lv ◽  
Ling Qiu ◽  
Guiqing Liu ◽  
Wei Wang ◽  
Ke Li ◽  
...  
Keyword(s):  
Controlled Release ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Targeted Delivery ◽  
Ruthenium Complex ◽  
Mesoporous Silica Nanoparticles ◽  
Ph Sensitive ◽  
Anticancer Effects

A pH sensitive mesoporous silica nanocarrier, RuNHC@MSNs-CTS-Biotin (CTS = chitosan), is developed for the targeted delivery and controlled release of a ruthenium(ii) N-heterocyclic carbene (RuNHC) complex.

Targeted delivery of quercetin loaded mesoporous silica nanoparticles to the breast cancer cells

2016 ◽  
Vol 1860 (10) ◽  
pp. 2065-2075 ◽  
Author(s):  
Abhijit Sarkar ◽  
Shatadal Ghosh ◽  
Sayantani Chowdhury ◽  
Bhawna Pandey ◽  
Parames C. Sil
Keyword(s):  
Breast Cancer ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Cancer Cells ◽  
Targeted Delivery ◽  
Breast Cancer Cells ◽  
Mesoporous Silica Nanoparticles

Selective topotecan delivery to cancer cells by targeted pH-sensitive mesoporous silica nanoparticles

RSC Advances ◽  
2016 ◽  
Vol 6 (56) ◽  
pp. 50923-50932 ◽  
Author(s):  
M. Martínez-Carmona ◽  
D. Lozano ◽  
M. Colilla ◽  
M. Vallet-Regí
Keyword(s):  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Cancer Cells ◽  
Delivery System ◽  
Mesoporous Silica Nanoparticles ◽  
Ph Sensitive

Topotecan targeted pH-sensitive delivery system based in mesoporous silica nanoparticles coated with a multifunctional biopolymer coating for cancer therapy.

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