Laser-Induced Graphene Electrochemical Immunosensor for Label-Free CEA Monitoring in Serum

Cost Effective ◽

Label Free ◽

Construction Of Self ◽

Electrochemical Devices ◽

The Cost

The cost-effective construction of self-designed conductive graphene patterns is crucial to the fabrication of graphene-based electrochemical devices. Here, a label-free Carcinoembryonic antigen (CEA) electrochemical immunosensor is developed based on surface...

Construction of electrochemical immunosensor based on redox hydrogel for ultrasensitive detection of carcinoembryonic antigen

New Journal of Chemistry ◽

10.1039/d1nj01282g ◽

2021 ◽

Author(s):

Xiangrong Huang ◽

Na Wu ◽

Wenxiu Liu ◽

Yazhuo Shang ◽

Honglai Liu ◽

...

Keyword(s):

Methylene Blue ◽

Electrochemical Detection ◽

Ultrasensitive Detection ◽

Label Free

In this work, a novel redox hydrogel was proposed for ultrasensitive label-free electrochemical detection of carcinoembryonic antigen (CEA). The redox hydrogel composed by cellulose nanocrystalline (CNC), methylene blue (MB), multi-walled...

Real-time determination of carcinoembryonic antigen by using a contactless electrochemical immunosensor

Analytical Methods ◽

10.1039/c6ay00822d ◽

2016 ◽

Vol 8 (24) ◽

pp. 4861-4866 ◽

Cited By ~ 6

Author(s):

Yan Jin ◽

Hongju Mao ◽

Qinghui Jin ◽

Jianlong Zhao

Keyword(s):

Detection Limit ◽

Real Time ◽

Specific Binding ◽

Label Free ◽

Time Interaction ◽

Time Determination ◽

Impedance Immunosensor

A sensitive label-free and contactless impedance immunosensor is developed for the real-time interaction investigation between a cancer biomarker carcinoembryonic antigen (CEA) and its antibody CEA 5909. The immunosensor is proved to have a specific binding process between CEA and CEA 5909 with a detection limit of 100 fg mL−1in PBS.

Label-Free Electrochemical Immunosensor Based on Gold and Iron-Oxide Nanoparticle Co-modified rGO-TEPA Hybrid for Sensitive Detection of Carcinoembryonic Antigen

Electrocatalysis ◽

10.1007/s12678-020-00604-z ◽

2020 ◽

Vol 11 (5) ◽

pp. 513-521

Author(s):

Haolin Xiao ◽

Shanshan Wei ◽

Zhencheng Chen ◽

Liangli Cao

Keyword(s):

Iron Oxide ◽

Sensitive Detection ◽

Iron Oxide Nanoparticle ◽

Label Free ◽

Oxide Nanoparticle

A novel label-free electrochemical immunosensor based on functionalized nitrogen-doped graphene quantum dots for carcinoembryonic antigen detection

Biosensors and Bioelectronics ◽

10.1016/j.bios.2016.11.029 ◽

2017 ◽

Vol 90 ◽

pp. 31-38 ◽

Cited By ~ 90

Author(s):

Yuying Yang ◽

Qing Liu ◽

Yan Liu ◽

Jianjian Cui ◽

Hui Liu ◽

...

Keyword(s):

Quantum Dots ◽

Graphene Quantum Dots ◽

Antigen Detection ◽

Label Free ◽

Nitrogen Doped ◽

Nitrogen Doped Graphene ◽

Doped Graphene

A novel label-free electrochemical immunosensor for carcinoembryonic antigen detection based on the [Ag–Ag2O]/SiO2 nanocomposite material as a redox probe

Journal of Electroanalytical Chemistry ◽

10.1016/j.jelechem.2010.03.014 ◽

2010 ◽

Vol 643 (1-2) ◽

pp. 15-19 ◽

Cited By ~ 26

Author(s):

Yali Yuan ◽

Ruo Yuan ◽

Yaqin Chai ◽

Ying Zhuo ◽

Li Mao ◽

...

Keyword(s):

Antigen Detection ◽

Nanocomposite Material ◽

Label Free ◽

Redox Probe

A label-free amperometric immunosensor for the detection of carcinoembryonic antigen based on novel magnetic carbon and gold nanocomposites

RSC Advances ◽

10.1039/c4ra16569a ◽

2015 ◽

Vol 5 (26) ◽

pp. 19961-19969 ◽

Cited By ~ 19

Author(s):

Faying Li ◽

Liping Jiang ◽

Jian Han ◽

Qing Liu ◽

Yunhui Dong ◽

...

Keyword(s):

Quantitative Detection ◽

Label Free ◽

Amperometric Immunosensor ◽

Magnetic Carbon ◽

Gold Nanocomposites

In this work, a novel label-free electrochemical immunosensor was developed for the quantitative detection of carcinoembryonic antigen (CEA).

Label-free electrochemical immunosensor for the carcinoembryonic antigen using a glassy carbon electrode modified with electrodeposited Prussian Blue, a graphene and carbon nanotube assembly and an antibody immobilized on gold nanoparticles

Microchimica Acta ◽

10.1007/s00604-013-0985-8 ◽

2013 ◽

Vol 180 (9-10) ◽

pp. 767-774 ◽

Cited By ~ 50

Author(s):

Dexiang Feng ◽

Xiaocui Lu ◽

Xiao Dong ◽

Yunyun Ling ◽

Yuzhong Zhang

Keyword(s):

Gold Nanoparticles ◽

Carbon Nanotube ◽

Prussian Blue ◽

Glassy Carbon Electrode ◽

Glassy Carbon ◽

Carbon Electrode ◽

Label Free

Label-free electrochemical immunosensor based on Nile blue A-reduced graphene oxide nanocomposites for carcinoembryonic antigen detection

Analytical Biochemistry ◽

10.1016/j.ab.2016.02.010 ◽

2016 ◽

Vol 500 ◽

pp. 80-87 ◽

Cited By ~ 33

Author(s):

Yan-Sha Gao ◽

Xiao-Fei Zhu ◽

Jing-Kun Xu ◽

Li-Min Lu ◽

Wen-Min Wang ◽

...

Keyword(s):

Graphene Oxide ◽

Reduced Graphene Oxide ◽

Nile Blue ◽

Antigen Detection ◽

Label Free ◽

Nile Blue A ◽

Reduced Graphene

A Label-Free Electrochemical Immunosensor for Carcinoembryonic Antigen Based on Graphene and Thionine

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.643.29 ◽

2013 ◽

Vol 643 ◽

pp. 29-32 ◽

Cited By ~ 1

Author(s):

Jing Man Han ◽

Zhan Fang Ma

Keyword(s):

Glassy Carbon ◽

Electrode Surface ◽

Au Nanoparticles ◽

Carbon Electrode ◽

Label Free ◽

Optimal Conditions ◽

Redox Species ◽

Electrode Surfaces

A label-free immunosensor was developed to detect the presence of an antigen. This immunosensor was based on the modulation of the electrochemistry of the surface bound redox species thionine (Thi). The model antigen was carcinoembryonic antigen (CEA) and the model epitope was the antibody of CEA (anti-CEA). Glassy carbon electrode surfaces were first drop-coated with a mixture of graphene, Thi and Nafion and air-dried. The electrode surface was then electrodeposited in HAuCl4solution to form Au nanoparticles (AuNPs). The resulted AuNPs were used to immobilize anti-CEA. Binding of CEA to the surface bound epitope resulted in the attenuation of the Thi electrochemistry. Under optimal conditions, the response of the label-free immunosensor had a liner range from 10 fg/mL to 100 ng/mL with a detection of 3.5 fg/mL (S/N=3).