scholarly journals Two-photon excitable boron complex based on tridentate imidazo[1,5-a]pyridine ligand for heavy-atom-free mitochondria-targeted photodynamic therapy

RSC Advances ◽  
2021 ◽  
Vol 11 (42) ◽  
pp. 26403-26407
Author(s):  
Keita Hoshi ◽  
Masami Itaya ◽  
Koki Tahara ◽  
Airi Matsumoto ◽  
Atsuhi Tabata ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Heavy Atom ◽  
Pyridine Ligand ◽  
Two Photon ◽  
Boron Complex ◽  
Targeted Photodynamic Therapy

We have synthesized a cyan fluorescent boron complex based on a tridentate imidazo[1,5-a]pyridine ligand.

A two-photon AIE fluorophore as a photosensitizer for highly efficient mitochondria-targeted photodynamic therapy

2020 ◽  
Vol 44 (22) ◽  
pp. 9355-9364 ◽  
Author(s):  
Qunshou Kong ◽  
Boxuan Ma ◽  
Tao Yu ◽  
Cheng Hu ◽  
Gaocan Li ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Two Photon ◽  
Highly Efficient ◽  
Targeted Photodynamic Therapy

Nowadays, photodynamic therapy (PDT) has become an effective method for cancer therapy.

Enhanced cancer therapy by the marriage of metabolic alteration and mitochondrial-targeted photodynamic therapy using cyclometalated Ir(iii) complexes

2017 ◽  
Vol 53 (71) ◽  
pp. 9878-9881 ◽  
Author(s):  
Jiangping Liu ◽  
Chengzhi Jin ◽  
Bo Yuan ◽  
Yu Chen ◽  
Xingguo Liu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Cancer Cell ◽  
Tumor Spheroids ◽  
Two Photon ◽  
Metabolic Alteration ◽  
Targeted Photodynamic Therapy

A series of DCA-Ir(iii) co-drug complexes were demonstrated to act in synergy by sensitizing cancer cell for PDT to achieve cancer-specifically enhanced two-photon PDT in the hypoxic muticellular tumor spheroids.

Inner salt-shaped small molecular photosensitizer with extremely enhanced two-photon absorption for mitochondrial-targeted photodynamic therapy

2017 ◽  
Vol 53 (10) ◽  
pp. 1680-1683 ◽  
Author(s):  
Wenbo Hu ◽  
Tingchao He ◽  
Rongcui Jiang ◽  
Jun Yin ◽  
Lin Li ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Photon Absorption ◽  
Mitochondrial Apoptosis ◽  
Apoptosis Pathway ◽  
Mitochondrial Apoptosis Pathway ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Highly Efficient ◽  
Targeted Photodynamic Therapy

An inner salt-shaped small-molecular photosensitizer with unprecedentedly strong two-photon absorption was developed for highly efficient two-photon photodynamic therapyviaa mitochondrial apoptosis pathway.

scholarly journals Fine-tuning the electronic structure of heavy-atom-free BODIPY photosensitizers for fluorescence imaging and mitochondria-targeted photodynamic therapy

2020 ◽  
Vol 11 (25) ◽  
pp. 6479-6484 ◽  
Author(s):  
Sujie Qi ◽  
Nahyun Kwon ◽  
Yubin Yim ◽  
Van-Nghia Nguyen ◽  
Juyoung Yoon
Keyword(s):  
Electronic Structure ◽  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Fluorescence Imaging ◽  
Heavy Atom ◽  
Fine Tuning ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Targeted Photodynamic Therapy ◽  
Mitochondria Targeting

We designed and investigated novel mitochondria-targeting heavy-atom-free BODIPY photosensitizers (R-BODs) that possessed considerable singlet oxygen generation abilities and good fluorescence properties for imaging-guided photodynamic therapy (PDT).

Design and synthesis of efficient heavy-atom-free photosensitizers for photodynamic therapy of cancer

2020 ◽  
Vol 56 (77) ◽  
pp. 11489-11492 ◽  
Author(s):  
Van-Nghia Nguyen ◽  
Sang Jun Park ◽  
Sujie Qi ◽  
Jeongsun Ha ◽  
Seonye Heo ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Heavy Atom ◽  
Design And Synthesis ◽  
Two Photon ◽  
Photodynamic Therapy Of Cancer

An effective approach to the design of photosensitizers was proposed and applied in two-photon excited photodynamic therapy of cancer.

Heavy atom enhanced generation of singlet oxygen in novel indenofluorene-based two-photon absorbing chromophores for photodynamic therapy

2015 ◽  
Vol 117 ◽  
pp. 7-15 ◽  
Author(s):  
Changquan Tang ◽  
Ping Hu ◽  
En Ma ◽  
Mingdong Huang ◽  
Qingdong Zheng
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Heavy Atom ◽  
Two Photon
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