scholarly journals Isolation of HLA-G+ cells using MEM-G/9 antibody-conjugated magnetic nanoparticles for prenatal screening: a reliable, fast and efficient method

RSC Advances ◽  
2021 ◽  
Vol 11 (49) ◽  
pp. 30990-31001
Author(s):  
Elaheh Emadi ◽  
Abdol-Khalegh Bordbar ◽  
Hamid Nadri ◽  
Ali Shams ◽  
Asghar Taheri-Kafrani ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Efficient Method ◽  
Prenatal Screening ◽  
Selective Isolation ◽  
Efficient Tool ◽  
Fetal Cells ◽  
G Cells

Selective isolation of HLA-G+ cells from HLA-G− cells with MEM-G/9-MNPs. It is an efficient tool for the isolation of fetal cells from the endocervical sample for prenatal screening.

scholarly journals Magnetofection In Vivo by Nanomagnetic Carriers Systemically Administered into the Bloodstream

Pharmaceutics ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1927
Author(s):  
Artem A. Sizikov ◽  
Petr I. Nikitin ◽  
Maxim P. Nikitin
Keyword(s):  
Magnetic Field ◽  
Magnetic Nanoparticles ◽  
Method Development ◽  
Magnetic Nanostructures ◽  
Field Application ◽  
Efficient Tool ◽  
Systemic Injection ◽  
Main Emphasis ◽  
The Magnetic Field

Nanoparticle-based technologies are rapidly expanding into many areas of biomedicine and molecular science. The unique ability of magnetic nanoparticles to respond to the magnetic field makes them especially attractive for a number of in vivo applications including magnetofection. The magnetofection principle consists of the accumulation and retention of magnetic nanoparticles carrying nucleic acids in the area of magnetic field application. The method is highly promising as a clinically efficient tool for gene delivery in vivo. However, the data on in vivo magnetofection are often only descriptive or poorly studied, insufficiently systematized, and sometimes even contradictory. Therefore, the aim of the review was to systematize and analyze the data that influence the in vivo magnetofection processes after the systemic injection of magnetic nanostructures. The main emphasis is placed on the structure and coating of the nanomagnetic vectors. The present problems and future trends of the method development are also considered.

l-Cysteine functionalized magnetic nanoparticles (LCMNP): a novel magnetically separable organocatalyst for one-pot synthesis of 2-amino-4H-chromene-3-carbonitriles in water

2015 ◽  
Vol 13 (28) ◽  
pp. 7772-7779 ◽  
Author(s):  
Ali Khalafi-Nezhad ◽  
Maryam Nourisefat ◽  
Farhad Panahi
Keyword(s):  
Magnetic Nanoparticles ◽  
Efficient Method ◽  
One Pot ◽  
One Pot Synthesis ◽  
Functionalized Magnetic Nanoparticles ◽  
Magnetically Separable

Magnetic nanoparticles were functionalized with l-cysteine using a new and efficient method and introduced as a novel magnetically separable organocatalyst.

Antifouling hydrogel-coated magnetic nanoparticles for selective isolation and recovery of circulating tumor cells

2021 ◽  
Author(s):  
Zhili Wang ◽  
Zeen Wu ◽  
Na Sun ◽  
Yi Cao ◽  
Xue Cai ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Selective Isolation

The antifouling hydrogel-coated magnetic nanoparticles were developed to realize the cell-friendly and efficient CTC capture and recovery.

Remote magnetically controlled drug release from electrospun composite nanofibers: design of a smart platform for therapy of psoriasis

2020 ◽  
Vol 75 (7) ◽  
pp. 587-591
Author(s):  
Natália Babincová ◽  
Oldřich Jirsák ◽  
Melánia Babincová ◽  
Peter Babinec ◽  
Mária Šimaljaková
Keyword(s):  
Magnetic Field ◽  
Magnetic Nanoparticles ◽  
Drug Release ◽  
Polyvinyl Alcohol ◽  
Efficient Method ◽  
Large Scale ◽  
Composite Nanofibers ◽  
Controlled Drug Release ◽  
Stimuli Responsive ◽  
Nano Fiber

AbstractAn efficient method for the large-scale fabrication of composite polyvinyl alcohol polymer nano fibers loaded with magnetic nanoparticles and methotrexate is reported in this study. We have demonstrated that nonwoven textile formed by needleless electro spinning is effective in immobilization and triggered the release of drugs, which is achieved by an alternating magnetic field induced heating of magnetic nanoparticles. This smart stimuli-responsive release ability, biocompatibility, and ultra-lightweight property render enormous potential for this electrospun nano fiber mat to be used as an anti-psoriatic drugs release platform, which may have far-reaching applications in dermatology.

An efficient method for synthesis of some heterocyclic compounds containing 3-iminoisatin and 1,2,4-triazole using Fe3O4 magnetic nanoparticles

2017 ◽  
Vol 38 (3) ◽  
pp. 279-290 ◽  
Author(s):  
Navabeh Nami ◽  
Daryoush Zareyee ◽  
Maryam Ghasemi ◽  
Ameneh Asgharzadeh ◽  
Mehdi Forouzani ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Efficient Method ◽  
Heterocyclic Compounds ◽  
Fe3o4 Magnetic Nanoparticles

scholarly journals An efficient multicomponent synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles catalyzed by a magnetic nanoparticle supported Lewis acidic deep eutectic solvent

RSC Advances ◽  
2019 ◽  
Vol 9 (65) ◽  
pp. 38148-38153 ◽  
Author(s):  
Thanh Thi Nguyen ◽  
Ngoc-Phuong Thi Le ◽  
The Thai Nguyen ◽  
Phuong Hoang Tran
Keyword(s):  
Magnetic Nanoparticles ◽  
Efficient Method ◽  
Magnetic Nanoparticle ◽  
Deep Eutectic Solvent ◽  
Multicomponent Synthesis ◽  
Highly Efficient ◽  
Tetrasubstituted Imidazoles

A mild and highly efficient method for the synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles catalyzed by a Lewis acidic deep eutectic solvent on magnetic nanoparticles (LADES@MNP).

scholarly journals Efficiency of Manual Scanning in Recovering Rare Cellular Events Identified by FluorescenceIn SituHybridization: Simulation of the Detection of Fetal Cells in Maternal Blood

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Ahmed Emad ◽  
Seemi Ayub ◽  
Oumar Samassékou ◽  
Marie-Chantal Grégoire ◽  
Macoura Gadji ◽  
...  
Keyword(s):  
Efficient Method ◽  
Unit Volume ◽  
Detection Efficiency ◽  
Maternal Blood ◽  
Fetal Cells ◽  
Cellular Events ◽  
Probe Hybridization ◽  
Rare Cells

Fluorescencein situhybridization (FISH) and manual scanning is a widely used strategy for retrieving rare cellular events such as fetal cells in maternal blood. In order to determine the efficiency of these techniques in detection of rare cells, slides of XX cells with predefined numbers (1–10) of XY cells were prepared. Following FISH hybridization, the slides were scanned blindly for the presence of XY cells by different observers. The average detection efficiency was 84% (125/148). Evaluation of probe hybridization in the missed events showed that 9% (2/23) were not hybridized, 17% (4/23) were poorly hybridized, while the hybridization was adequate for the remaining 74% (17/23). In conclusion, manual scanning is a relatively efficient method to recover rare cellular events, but about 16% of the events are missed; therefore, the number of fetal cells per unit volume of maternal blood has probably been underestimated when using manual scanning.

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