Mescaline-induced changes of brain-cortex ribosomes. Effect of mescaline on the stability of brain-cortex ribosomes
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1. During the action of mescaline sulphate on goat brain-cortex slices the ribosomal particles become susceptible to breakdown, releasing protein, RNA, acidsoluble nucleotides and ninhydrin-positive materials, resulting in loss of ribosomal enzyme activities. 2. Ribosomes of the mescaline-treated cortex slices undergo rapid degradation in the presence of trypsin and ribonuclease. 3. Mescaline does not alter the chemical and nucleotide compositions or the u.v.-absorption characteristics of ribosomal particles, however.
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1977 ◽
Vol 55
(3)
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pp. 356-362
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1961 ◽
Vol 39
(3)
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pp. 551-558
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1971 ◽
Vol 18
(2)
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pp. 259-265
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2009 ◽
Vol 25
(S4)
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pp. 75-75
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