scholarly journals Functional divergence between the two P1–P2 stalk dimers on the ribosome in their interaction with ricin A chain

2014 ◽  
Vol 460 (1) ◽  
pp. 59-69 ◽  
Author(s):  
Przemysław Grela ◽  
Xiao-Ping Li ◽  
Marek Tchórzewski ◽  
Nilgun E. Tumer
Keyword(s):  
Functional Divergence ◽  
Wild Type ◽  
Ricin A Chain ◽  
Yeast Ribosomes ◽  
A Chain ◽  
Wild Type Yeast ◽  
Ricin A

Wild-type yeast ribosomes and ribosomes bearing only the P1B–P2A dimer bound to the ricin A chain better and were more susceptible to depurination and toxicity than ribosomes bearing only the P1A–P2B dimer, indicating that the two stalk dimers differ in their function.

scholarly journals Ribosome inactivation by ricin A chain: a sensitive method to assess the activity of wild-type and mutant polypeptides.

1989 ◽  
Vol 8 (1) ◽  
pp. 301-308 ◽  
Author(s):  
M. J. May ◽  
M. R. Hartley ◽  
L. M. Roberts ◽  
P. A. Krieg ◽  
R. W. Osborn ◽  
...  
Keyword(s):  
Wild Type ◽  
Ricin A Chain ◽  
Ribosome Inactivation ◽  
A Chain ◽  
Mutant Polypeptides ◽  
Ricin A ◽  
Sensitive Method

Alteration of an amino acid residue outside the active site of the ricin A chain reduces its toxicity towards yeast ribosomes

1991 ◽  
Vol 230 (1-2) ◽  
pp. 81-90 ◽  
Author(s):  
Jane H. Gould ◽  
Martin R. Hartley ◽  
Philip C. Welsh ◽  
Deborah K. Hoshizaki ◽  
Arthur Frankel ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Residue ◽  
Active Site ◽  
Ricin A Chain ◽  
Yeast Ribosomes ◽  
A Chain ◽  
Ricin A

Cell ablation using wild-type and cold-sensitive ricin-a chain indrosophila embryonic mesoderm

genesis ◽  
2002 ◽  
Vol 34 (1-2) ◽  
pp. 132-134 ◽  
Author(s):  
Marcus J. Allen ◽  
Cahir J. O'Kane ◽  
Kevin G. Moffat
Keyword(s):  
Wild Type ◽  
Ricin A Chain ◽  
Cell Ablation ◽  
Cold Sensitive ◽  
A Chain ◽  
Ricin A
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