The Relationship between Maternal Blood Pressure & Infant Birth Weight

1995 ◽  
Vol 88 (s32) ◽  
pp. 2P-2P ◽  
Author(s):  
D Churchill ◽  
DG Beevers
Keyword(s):  
Blood Pressure ◽  
Birth Weight ◽  
Maternal Blood ◽  
Infant Birth ◽  
The Relationship ◽  
Maternal Blood Pressure

scholarly journals Maternal hypertension-related genes affect the fetal growth via placenta

2021 ◽  
Author(s):  
Noriko Sato ◽  
Ayako Fudono ◽  
Chihiro Imai ◽  
Hidemi Takimoto ◽  
Iori Tarui ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Metabolic Diseases ◽  
Mendelian Randomization ◽  
Maternal Blood ◽  
Low Birth Weight Infants ◽  
Maternal Hypertension ◽  
The Relationship ◽  
Maternal Blood Pressure

Abstract Low birth weight is associated with the development of cardio-metabolic diseases later in life1-4. A recent Mendelian Randomization Study concluded that the susceptibility of low-birth-weight infants to develop hypertension during adulthood is due to the inheritance of hypertension genes from the mother, and not to an unfavorable intrauterine environment5. Therein, it has been assumed that low birth weight is caused by maternal hypertension5,6, although there is no evidence to support such a linear relationship. In the present study, we have noted that most of blood pressure SNPs are related to vascular regulation7-9 and found that the relationship between maternal blood pressure-increasing polygenic score and reduction of offspring birth weight is mediated by a reduced growth of the placenta but not by the mother's high blood pressure. This suggests that the risk of hypertension of low-birth-weight infants may result from a poor placental environment.

Maternal blood pressure levels prepartum correlate with neonatal birth weight in preeclampsia

2019 ◽  
Vol 47 (8) ◽  
pp. 894-896
Author(s):  
Viola Leidner ◽  
Filiz Markfeld-Erol ◽  
Matthias Wuttke ◽  
Mirjam Kunze ◽  
Julia Jacobs ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Birth Weight ◽  
Maternal Blood ◽  
Neonatal Birth Weight ◽  
Maternal Blood Pressure

scholarly journals Maternal blood pressure in pregnancy, birth weight, and perinatal mortality in first births: prospective study

BMJ ◽  
2004 ◽  
Vol 329 (7478) ◽  
pp. 1312 ◽  
Author(s):  
Philip J Steer ◽  
Mark P Little ◽  
Tina Kold-Jensen ◽  
Jean Chapple ◽  
Paul Elliott
Keyword(s):  
Blood Pressure ◽  
Birth Weight ◽  
Prospective Study ◽  
Perinatal Mortality ◽  
Maternal Blood ◽  
Maternal Blood Pressure ◽  
In Pregnancy

scholarly journals Maternal Blood Pressure in Relation to Birth Outcomes and Consumption of a Lipid-Based Nutrient Supplement (P11-001-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Alyssa Abreu ◽  
Rebecca Young ◽  
Ashley Buchanan ◽  
Ingrid Lofgren ◽  
Harriet Okronipa ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Birth Outcomes ◽  
Head Circumference ◽  
Maternal Blood ◽  
Adverse Birth Outcomes ◽  
Lower Birth Weight ◽  
The Impact ◽  
Maternal Blood Pressure

Abstract Objectives It is unknown whether prenatal lipid-based nutrient supplements (LNS) affect blood pressure. The cutoffs to define high blood pressure have recently changed and little research has examined the association between the newly proposed blood pressure cutoffs and birth outcomes. Our objectives were to assess 1) the impact of LNS on maternal blood pressure; and 2) the association between blood pressure and birth outcomes. Methods In total, 1320 pregnant women ≤ 20 wk gestation in Ghana were randomized to receive daily either: 1) iron and folic acid (IFA), 2) multiple micronutrients (MMN), or 3) LNS. Blood pressure was measured at enrollment and 36 wk gestation. Gestational age was determined by ultrasound and newborn anthropometry included weight, length, and head circumference. The effect of LNS on maternal blood pressure was analyzed using ANOVA and associations between maternal blood pressure and birth outcomes were examined by linear and logistic regressions. Results Mean (± SD) systolic and diastolic blood pressure (SBP and DBP) at 36 wk gestation were 110 ± 11 and 63 ± 8 mmHg, respectively, and did not differ by supplementation group (P > 0.05). At enrollment, higher DBP was associated with lower birth weight and shorter pregnancy duration; 6.6% of women had high SBP (≥ 130 mmHg) and 3.6% had high DBP (≥ 80 mmHg), and women with high DBP had greater odds of low birth weight (adjusted OR = 2.99 (95% CI = 1.04, 8.62)) and preterm birth (3.99 (1.46, 10.86)) but there were no significant associations with SBP. At 36 wk, higher SBP was associated with a lower birth weight, birth length, newborn head circumference, and a shorter pregnancy duration and higher DBP was associated with a lower birth weight and length; 4.3% of women had high SBP and 2.4% had high DBP and women with high DBP had greater odds of low birth weight (4.14 (1.26, 13.62)) but high SBP (≥ 130 mmHg) was not associated with any birth outcomes. Conclusions Daily LNS during pregnancy did not have a significant effect on maternal blood pressure compared with IFA or MMN in this setting. Both higher SBP and higher DBP were associated with a shorter pregnancy duration and birth size; however, only high DBP was associated with adverse birth outcomes. It is unclear whether the new cutoff for high SBP is useful for identifying pregnancies at risk for adverse birth outcomes. Funding Sources Funded through a grant from the Bill & Melinda Gates Foundation to the University of California, Davis.

scholarly journals The Association between Preeclampsia and Newborn Hearing Loss

2019 ◽  
pp. 255-261
Author(s):  
Siti R. Nanin ◽  
Ansyori Hatta ◽  
Alibasyah A. Chakra ◽  
Ghanie Abla ◽  
Legiran Legiran
Keyword(s):  
Blood Pressure ◽  
Hearing Loss ◽  
Birth Weight ◽  
Demographic Data ◽  
Maternal Blood ◽  
Demographic Characteristics ◽  
T Test ◽  
Bivariate Analysis ◽  
Newborn Hearing ◽  
The Relationship

Objective: to analyze the relationship between PE and the newborn hearing loss  Method : Analytic observation research withcross sectionaldesign performed inRSMHPalembangsince December 2016 to July 2017, obtained 48 aterm neonates born from mother diagnosed with PE (11 PE and 37 severe PE). Measurements of neonatal hearing loss then performed using emission otoacoustics (OAE) in both ears by ENT division with catagories intepretation of pass and refer. The mothers were physically check and interviewed to obtain demographic data and obstetric history. After the data normality were proved byShapiro Wilktest, we performed bivariate analysis using X2test on demographic and obstetric characteristics of the mother, neonatal demographic characteristics, and determine the relationship of PE with OAE result. The ratio of systolic (SBP) and diastolic (DBP) blood pressure to neonatal hearing loss was determined by independent T test and ROC test. Multivariate analysis was performed to determine the maternal and neonatal risk factors that influenced neonatal hearing loss. Data analysis using SPSS version 18.0.  Results : There were no significant differences in maternal and neonatal demographic characteristics in neonatal hearing loss (p> 0.05). No significant relationship was found between PE and OAE of both ear (right, p = 0,437; left, p = 0,368). There was difference of mean of SBP and DBP of mother inneonate OAE of both ears (p <0,05) with cut off point of SBP 160 mmHg and DBP 106 mmHg.There was a significant association between DBP (> 106 mmHg) of the mother and birth weight of the fetus (< 2500 g) with referOAE.     Conclusion: There was a significant association between neonatal hearing loss and maternal PE, determined primarily by maternal DBP, and neonatal birth weight. Keywords: maternal blood pressure, OAE,preeclampsia,   Abstrak Tujuan: untuk menilai hubungan PE ibu dengan penurunan pendengarah bayyi baru lahir Metode: Penelitian observasi analitik dengan disain cross sectionaldilakukan di RSMH Palembang sejak Desember 2016 sampai Juli 2017, diperoleh 48 neonatus aterm lahir dari ibu PE (11 PER dan 37 PEB). Neonatus dilakukan pengukuran pendengaran menggunakan otoakustik emisi (OAE) pada kedua telinga oleh divisi THT dengan kategori intepretasi refer dan pass. Ibu dilakukan pemeriksaan dan wawancara untuk memperoleh data demografi dan riwayat obstetri. Setelah normalitas data dibuktikan dengan tes Saphiro Wilk, dilakukan analisis bivariat menggunakan tes X2 pada karakteristik demografi dan obstetri Ibu, karakteristik demografi neonatus, dan menentukan hubungan preeklampsia dengan hasil OAE. Perbandingan tekanan darah sistolik (TDS) dan diastolik (TDD) terhadap penurunan pendengaran neonatus ditentukan dengan independent T test dan uji ROC. Analisis multivariat dilakukan untuk menentukan faktor risiko Ibu maupun neonatus yang berpengaruh terhadap penurunan pendengaran neonatus. Analisa data menggunakan SPSS versi 18.0. Hasil: Tidak ditemukan perbedaan signifikan karakteristik demografi Ibu maupun neonatus tehadap penurunan pendengaran neonatus (p>0,05). Tidak ditemukan hubungan signfikan antara kondisi PE dengan OAE kanan (p = 0,437) dan kiri (p = 0,368). Ditemukan perbedaan rerata TDS dan TDD ibu terhadap OAE kedua telinga neonatus (p<0,05) dengan cut off point TDS 160 mmHg dan TDD 106 mmHg. Ditemukan hubungan signifikan antara TDD (>106 mmHg) ibu dan berat lahir janin (>2500 gr) dengan OAE refer. Kesimpulan: Terdapat hubungan bermakna antara penurunan pendengaran neonatus dengan kondisi preeklampsia ibu, yang ditentukan terutama oleh TDD ibu, serta berat lahir bayi. Kata kunci:, OAE, preeklamsia, tekanan darah

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