Functional Neuroimaging of Speech Production in People Who Stutter

AbstractArticulography and functional neuroimaging are two major tools for studying the neurobiology of speech production. Until now, however, it has generally not been possible to use both in the same experimental setup because of technical incompatibilities between the two methodologies. Here we describe results from a novel articulography system dubbed Magneto-articulography for the Assessment of Speech Kinematics (MASK), used for the first time to obtain kinematic profiles of oro-facial movements during speech together with concurrent magnetoencephalographic (MEG) measurements of neuromotor brain activity. MASK was used to characterise speech kinematics in a healthy adult, and the results were compared to measurements from the same participant with a conventional electromagnetic articulography (EMA) setup. We also characterised speech movement kinematics with MASK in a group of ten typically developing children, aged 8-12 years. Analyses targeted the gestural landmarks of the utterances /ida/, /ila/ and reiterated productions of /pataka/. These results demonstrate that the MASK technique can be used to reliably characterise movement profiles and kinematic parameters that reflect development of speech motor control, together with MEG measurements of brain responses from speech sensorimotor cortex. This new capability sets the stage for cross-disciplinary efforts to understand the developmental neurobiology of human speech production.

Download Full-text

Functional Neuroimaging of Speech Production

Handbook of Psycholinguistics ◽

10.1016/b978-012369374-7/50006-7 ◽

2006 ◽

pp. 125-150

Author(s):

Thomas A. Zeffiro ◽

Jennifer L. Frymiare

Keyword(s):

Speech Production ◽

Functional Neuroimaging

Download Full-text

Prosodic Impairment in Dementia: Review of the Literature

Current Alzheimer Research ◽

10.2174/1567205014666171030115624 ◽

2018 ◽

Vol 15 (2) ◽

pp. 157-163 ◽

Cited By ~ 5

Author(s):

Sylwia Misiewicz ◽

Adam M. Brickman ◽

Giuseppe Tosto

Keyword(s):

Alzheimer’S Disease ◽

Speech Production ◽

Neuronal Networks ◽

Right Hemisphere ◽

Functional Neuroimaging ◽

Spoken Language ◽

Frontal Area ◽

Emotional Prosody ◽

Review Of The Literature ◽

The Right

Objective: Prosody, an important aspect of spoken language, is defined as the emphasis placed on certain syllables, changes in tempo or timing, and variance in pitch and intonation. Most studies investigating expression and comprehension of prosody have focused primarily on emotional prosody and less extensively on supralexical prosody. The distinction is indeed important, as the latter conveys information such as interrogative or assertive mode, whereas the former delivers emotional connotation, such as happiness, anger, and sadness. These functions appear to rely on distinct neuronal networks, supported by functional neuroimaging studies that show activation of the right hemisphere, specifically in the right inferior frontal area during emotional detection. Conclusion: This review summarizes the studies conducted on prosody impairment in Alzheimer's disease and other dementias, with emphasis on experiments designed to investigate the emotional vs. the supralexical aspect of speech production. We also discussed the available tools validated to test and quantify the prosodic impairment.

Download Full-text

Error in the Superior Temporal Gyrus? A Systematic Review and Activation Likelihood Estimation Meta-Analysis of Speech Production Studies

Journal of Cognitive Neuroscience ◽

10.1162/jocn_a_01661 ◽

2020 ◽

pp. 1-23

Author(s):

Sophie Meekings ◽

Sophie K. Scott

Keyword(s):

Systematic Review ◽

Error Correction ◽

Speech Production ◽

Auditory Feedback ◽

Functional Neuroimaging ◽

Meta Analysis ◽

Likelihood Estimation ◽

Superior Temporal Gyrus ◽

Activation Likelihood Estimation ◽

Production Studies

Evidence for perceptual processing in models of speech production is often drawn from investigations in which the sound of a talker's voice is altered in real time to induce “errors.” Methods of acoustic manipulation vary but are assumed to engage the same neural network and psychological processes. This article aims to review fMRI and PET studies of altered auditory feedback and assess the strength of the evidence these studies provide for a speech error correction mechanism. Studies included were functional neuroimaging studies of speech production in neurotypical adult humans, using natural speech errors or one of three predefined speech manipulation techniques (frequency altered feedback, delayed auditory feedback, and masked auditory feedback). Seventeen studies met the inclusion criteria. In a systematic review, we evaluated whether each study (1) used an ecologically valid speech production task, (2) controlled for auditory activation caused by hearing the perturbation, (3) statistically controlled for multiple comparisons, and (4) measured behavioral compensation correlating with perturbation. None of the studies met all four criteria. We then conducted an activation likelihood estimation meta-analysis of brain coordinates from 16 studies that reported brain responses to manipulated over unmanipulated speech feedback, using the GingerALE toolbox. These foci clustered in bilateral superior temporal gyri, anterior to cortical fields typically linked to error correction. Within the limits of our analysis, we conclude that existing neuroimaging evidence is insufficient to determine whether error monitoring occurs in the posterior superior temporal gyrus regions proposed by models of speech production.

Download Full-text

The Need for a Broad-Based Model of Phonological Disorders

Language Speech and Hearing Services in Schools ◽

10.1044/0161-1461.2303.261 ◽

1992 ◽

Vol 23 (3) ◽

pp. 261-268 ◽

Cited By ~ 24

Author(s):

Alan G. Kamhi

Keyword(s):

Speech Production ◽

Phonological Disorders ◽

Production Processes ◽

Assessment And Treatment ◽

Speech Delays ◽

Explanatory Adequacy ◽

State Of Affairs ◽

Assessment Procedures ◽

Treatment Procedures

My response to Fey’s article (1985; reprinted 1992, this issue) focuses on the confusion caused by the application of simplistic phonological definitions and models to the assessment and treatment of children with speech delays. In addition to having no explanatory adequacy, such definitions/models lead either to assessment and treatment procedures that are similarly focused or to procedures that have no clear logical ties to the models with which they supposedly are linked. Narrowly focused models and definitions also usually include no mention of speech production processes. Bemoaning this state of affairs, I attempt to show why it is important for clinicians to embrace broad-based models of phonological disorders that have some explanatory value. Such models are consistent with assessment procedures that are comprehensive in nature and treatment procedures that focus on linguistic, as well as motoric, aspects of speech.

Download Full-text

A Family With Autosomal-Dominant Progressive Sensorineural Hearing Loss

American Journal of Audiology ◽

10.1044/1059-0889.0501.23 ◽

1996 ◽

Vol 5 (1) ◽

pp. 23-32 ◽

Cited By ~ 3

Author(s):

Chris Halpin ◽

Barbara Herrmann ◽

Margaret Whearty

Keyword(s):

Speech Production ◽

Hearing Aids ◽

Role Models ◽

Speech Intelligibility ◽

Large Scale ◽

Speech Language Pathology ◽

The Family ◽

Patient Will ◽

Language Pathology

The family described in this article provides an unusual opportunity to relate findings from genetic, histological, electrophysiological, psychophysical, and rehabilitative investigation. Although the total number evaluated is large (49), the known, living affected population is smaller (14), and these are spread from age 20 to age 59. As a result, the findings described above are those of a large-scale case study. Clearly, more data will be available through longitudinal study of the individuals documented in the course of this investigation but, given the slow nature of the progression in this disease, such studies will be undertaken after an interval of several years. The general picture presented to the audiologist who must rehabilitate these cases is that of a progressive cochlear degeneration that affects only thresholds at first, and then rapidly diminishes speech intelligibility. The expected result is that, after normal language development, the patient may accept hearing aids well, encouraged by the support of the family. Performance and satisfaction with the hearing aids is good, until the onset of the speech intelligibility loss, at which time the patient will encounter serious difficulties and may reject hearing aids as unhelpful. As the histological and electrophysiological results indicate, however, the eighth nerve remains viable, especially in the younger affected members, and success with cochlear implantation may be expected. Audiologic counseling efforts are aided by the presence of role models and support from the other affected members of the family. Speech-language pathology services were not considered important by the members of this family since their speech production developed normally and has remained very good. Self-correction of speech was supported by hearing aids and cochlear implants (Case 5’s speech production was documented in Perkell, Lane, Svirsky, & Webster, 1992). These patients received genetic counseling and, due to the high penetrance of the disease, exhibited serious concerns regarding future generations and the hope of a cure.

Download Full-text

Application of concepts from Cross-Recurrence Analysis in speech production: An overview and a comparison to other nonlinear methods

Journal of Speech Language and Hearing Research ◽

10.1044/2013_jslhr-s-12-0223 ◽

2013 ◽

Author(s):

L. Lancia ◽

S. Fuchs ◽

M. Tiede

Keyword(s):

Speech Production ◽

Recurrence Analysis ◽

Nonlinear Methods

Download Full-text

Effects of Concurrent Manual Task Performance on Connected Speech Acoustics in Individuals With Parkinson Disease

Journal of Speech Language and Hearing Research ◽

10.1044/2019_jslhr-s-msc18-18-0190 ◽

2019 ◽

Vol 62 (7) ◽

pp. 2099-2117 ◽

Cited By ~ 2

Author(s):

Jason A. Whitfield ◽

Zoe Kriegel ◽

Adam M. Fullenkamp ◽

Daryush D. Mehta

Keyword(s):

Task Performance ◽

Speech Production ◽

Dual Task ◽

Motor Task ◽

Task Condition ◽

Connected Speech ◽

Speech Acoustics ◽

Single Task ◽

Manual Task ◽

Task Conditions

Purpose Prior investigations suggest that simultaneous performance of more than 1 motor-oriented task may exacerbate speech motor deficits in individuals with Parkinson disease (PD). The purpose of the current investigation was to examine the extent to which performing a low-demand manual task affected the connected speech in individuals with and without PD. Method Individuals with PD and neurologically healthy controls performed speech tasks (reading and extemporaneous speech tasks) and an oscillatory manual task (a counterclockwise circle-drawing task) in isolation (single-task condition) and concurrently (dual-task condition). Results Relative to speech task performance, no changes in speech acoustics were observed for either group when the low-demand motor task was performed with the concurrent reading tasks. Speakers with PD exhibited a significant decrease in pause duration between the single-task (speech only) and dual-task conditions for the extemporaneous speech task, whereas control participants did not exhibit changes in any speech production variable between the single- and dual-task conditions. Conclusions Overall, there were little to no changes in speech production when a low-demand oscillatory motor task was performed with concurrent reading. For the extemporaneous task, however, individuals with PD exhibited significant changes when the speech and manual tasks were performed concurrently, a pattern that was not observed for control speakers. Supplemental Material https://doi.org/10.23641/asha.8637008

Download Full-text