Post-infectious central and peripheral nervous system diseases in patient with Devic's disease and Guillain-Barre syndrome

2003 ◽  
Vol 10 (5) ◽  
pp. 600-600 ◽  
Author(s):  
R. J. Hawley ◽  
R. Madrid
2012 ◽  
Vol 11 (4) ◽  
pp. 231-233
Author(s):  
Tamer Shalaby ◽  
◽  
Constantinos Papoutsos ◽  
Louise Tiemens ◽  
Iain Crossingham ◽  
...  

Guillain-Barré syndrome (GBS) is an acute demyelinating disorder of the peripheral nervous system that results in motor weakness, absent reflexes and autonomic nervous system dysfunction. Autonomic failure is reported in approximately 65 % of patientswith GBS and usually follows extensive motor involvement. In this case our patient presented with syncope and other signs of autonomic failure before the motor weakness developed. Few cases in the literature have reported features of autonomic failure before established weakness in GBS; to our knowledge, syncope has not been described previously as a presenting feature of GBS.


Neurology ◽  
2017 ◽  
Vol 89 (6) ◽  
pp. 611-615 ◽  
Author(s):  
Stéphane Mathis ◽  
Jean-Michel Vallat

Jules Dejerine (1849–1917) was a French neurologist who contributed to the description of numerous neurologic conditions ranging from neurovascular pathology to neuromuscular disorders. A considerable body of his research was devoted to the peripheral nervous system. In this area, the eponymous Dejerine-Sottas syndrome refers to a form of infantile hereditary neuropathy. Dejerine also contributed to the description of many other disorders of the peripheral nervous system and was even a precursor in the study of acquired neuropathies (as well as acute inflammatory neuropathies, before the first description of the Guillain-Barré syndrome) and in the field of radicular pathology. In this centennial year of his death, we emphasize the variety and originality of Dejerine’s opus on diseases of the peripheral nervous system.


2020 ◽  
Vol 48 (4) ◽  
pp. 285-289
Author(s):  
A. Yu. Ryabchenko ◽  
E. V. Grankin

Guillain-Barré syndrome is an orphan autoimmune disease associated with the involvement of the peripheral nervous system. The clinical course of the syndrome has four main types. We present a clinical case of Guillain-Barré syndrome in a 6-year old child. Against the background of a previous infection, he developed oculomotor dysfunction, peripheral tetraparesis, sensory abnormalities with subsequent severe weakness of the respiratory muscles. The differential diagnosis included inflammatory, infectious and neoplastic spinal cord disorders, spinal cord magnetic resonance imaging, and examination of the cerebrospinal fluid. The patient's electromyographic data confirmed peripheral nerve damage. Based on all of these, the patient was diagnosed with Guillain-Barré syndrome. Specific treatment, including plasmapheresis and intravenous human immunoglobulin G at a dose of 0.4 mg daily for 5 days, and symptomatic treatment resulted in gradual improvement and complete regression of the neurological symptoms completely resolved. Since Guillain-Barré syndrome is a rare disease of the peripheral nervous system, the awareness of the specifics of its clinical course allows for earlier correct diagnosis and effective treatment.


2020 ◽  
Vol 7 (3) ◽  
pp. 156-161
Author(s):  
Hossein Mozhdehipanah ◽  
Sepideh Paybast ◽  
Reza Gorji

The novel coronavirus disease 2019 (COVID-19) is a global pandemic. Although the main clinical manifestations of the COVID-19 infection have confined to the respiratory system, there is some evidence suggesting the neuro-invasive potential of the COVID-19. There are limited reports of Guillain–Barré syndrome (GBS) as a peripheral nervous system complication of COVID-19 infection. We described four patients with COVID-19 infection who developed acute polyneuropathy with a final diagnosis of Guillain–Barré syndrome. COVID-19 may have the potential to invade the peripheral nervous system. GBS, as one of the critical neurological complications of COVID-19, could be considered as a post-infectious event.


2020 ◽  
Vol 15 (2) ◽  
pp. 55-59
Author(s):  
A. S. Kotov ◽  
E. V. Mukhina ◽  
A. V. Shatalin ◽  
M. V. Panteleeva ◽  
M. S. Bunak

Guillain–Barré syndrome – an acute demyelinating autoimmune disease characterized by lesions of the peripheral nervous system and consequently peripheral paralysis, paresthesias and/or pain. Guillain–Barré syndrome is a predominant cause of acute flaccid paralysis, which may occur at any age. We present two clinical cases of flaccid paralysis with patients at the age of 7 and 5 years requiring verification of the diagnosis.


2015 ◽  
Vol 2015 ◽  
pp. 1-12 ◽  
Author(s):  
Ying Wang ◽  
Shuang Sun ◽  
Jie Zhu ◽  
Li Cui ◽  
Hong-Liang Zhang

Guillain-Barré syndrome (GBS), the axonal subtype of which is mainly triggered byC. jejuniwith ganglioside-mimicking lipooligosaccharides (LOS), is an immune-mediated disorder in the peripheral nervous system (PNS) accompanied by the disruption of the blood-nerve barrier (BNB) and the blood-cerebrospinal fluid barrier (B-CSF-B). Biomarkers of GBS have been extensively explored and some of them are proved to assist in the clinical diagnosis and in monitoring disease progression as well as in assessing the efficacy of immunotherapy. Herein, we systemically review the literature on biomarkers of GBS, including infection-/immune-/BNB, B-CSF-B, and PNS damage-associated biomarkers, aiming at providing an overview of GBS biomarkers and guiding further investigations. Furthermore, we point out further directions for studies on GBS biomarkers.


2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Gregory Griffin ◽  
Brittany Cunningham ◽  
Jonathan M. Beary ◽  
Yonatan Spolter ◽  
Richard Gandee ◽  
...  

Guillain–Barré syndrome (GBS) is a rare acute demyelinating syndrome of the peripheral nervous system that is commonly preceded by infection. Vaccinations have also been associated with an increased incidence of GBS, though the risk is low. Caution with revaccination is recommended in patients with a history of GBS. Risks of revaccination compared with the risks of influenza complications should be considered. Patients who experience GBS after vaccination have not been shown to have an increased incidence of recurrent GBS after the influenza vaccine, though evidence is limited. We report a case of recurrent GBS in a patient following the influenza vaccine.


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