MMPI Profile as an Outcome “Predictor” in the Treatment of Noncancer Pain Patients Utilizing Intraspinal Opioid Therapy

2001 ◽  
Vol 4 (3) ◽  
pp. 93-97 ◽  
Author(s):  
Daniel M. Doleys ◽  
Jessica Brown
Keyword(s):  
Opioid Therapy ◽  
Outcome Predictor ◽  
Noncancer Pain ◽  
Pain Patients ◽  
Mmpi Profile

scholarly journals Efficacy and Practicality of Opioid Therapy in Japanese Chronic Noncancer Pain Patients

2019 ◽  
Vol 20 (3) ◽  
pp. 222-231 ◽  
Author(s):  
Yukari Shindo ◽  
Soushi Iwasaki ◽  
Michiaki Yamakage
Keyword(s):  
Opioid Therapy ◽  
Chronic Noncancer Pain ◽  
Noncancer Pain ◽  
Pain Patients

scholarly journals Health care resource use and cost differences by opioid therapy type among chronic noncancer pain patients

2017 ◽  
Vol Volume 10 ◽  
pp. 1713-1722 ◽  
Author(s):  
Pamela Landsman-Blumberg ◽  
Nathaniel Katz ◽  
Kavita Gajria ◽  
Anna D’Souza ◽  
Sham L Chaudhari ◽  
...  
Keyword(s):  
Health Care ◽  
Resource Use ◽  
Opioid Therapy ◽  
Health Care Resource ◽  
Chronic Noncancer Pain ◽  
Health Care Resource Use ◽  
Noncancer Pain ◽  
Pain Patients ◽  
Cost Differences

Monitoring outcomes during long-term opioid therapy for noncancer pain: Results with the Pain Assessment and Documentation Tool

2005 ◽  
Vol 1 (5) ◽  
pp. 257 ◽  
Author(s):  
Steven D. Passik, PhD ◽  
Kenneth L. Kirsh, PhD ◽  
Laurie Whitcomb, MA ◽  
Jeffrey R. Schein, PhD, MPH ◽  
Mitchell A. Kaplan, PhD ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Side Effects ◽  
Pain Assessment ◽  
The United States ◽  
Opioid Therapy ◽  
Chronic Pain Patients ◽  
Noncancer Pain ◽  
Documentation Tool ◽  
Pain Patients

The increasingly common practice of long-term opioid therapy for chronic noncancer pain must be guided by ongoing assessment of four types of outcomes: pain relief, function, side effects, and drug-related behaviors. Our objective was to gather initial pilot data on the clinical application of a specialized chart note, the Pain Assessment and Documentation Tool (PADT), which was developed and tested with 27 physicians. This pilot test provided the means to collect cross-sectional outcome data on a large sample of opioid-treated chronic pain patients. Each of the physician volunteers (located in a variety of settings across the United States) completed the PADT for a convenience sample of personally treated chronic pain patients who had received at least three months of opioid therapy. Completion of the PADT required a clinical interview, review of the medical chart, and direct clinical observation. Data from the PADTs were collated and analyzed. The results suggested that the majority of patients with chronic pain achieve relatively positive outcomes in the eyes of their prescribing physicians in all four relevant domains with opioid therapy. Analgesia was modest but meaningful, functionality was generally stabilized or improved, and side effects were tolerable. Potentially aberrant behaviors were common but viewed as an indicator of a problem (i.e., addiction or diversion) in only approximately 10 percent of cases. Using the PADT, physician ratings can be developed in four domains. In this sample, outcomes suggested that opioid therapy provided meaningful analgesia.

scholarly journals Peripherally acting μ-opioid receptor antagonists as treatment options for constipation in noncancer pain patients on chronic opioid therapy

2017 ◽  
Vol Volume 11 ◽  
pp. 107-119 ◽  
Author(s):  
Joseph Pergolizzi Jr ◽  
Robert B Raffa ◽  
Marco Pappagallo ◽  
Charles Fleischer ◽  
Joseph Pergolizzi, III ◽  
...  
Keyword(s):  
Opioid Receptor ◽  
Treatment Options ◽  
Opioid Therapy ◽  
Mu Opioid Receptor ◽  
Chronic Opioid Therapy ◽  
Receptor Antagonists ◽  
Mu Opioid ◽  
Opioid Receptor Antagonists ◽  
Noncancer Pain ◽  
Pain Patients

What is the most effective tapering method for weaning chronic opioid therapy in noncancer pain patients?

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Rubin Varghese ◽  
Dakota Price ◽  
Jeremy Crider ◽  
J.T. Epting ◽  
Daniel Hurst
Keyword(s):  
Opioid Therapy ◽  
Chronic Opioid Therapy ◽  
Noncancer Pain ◽  
Pain Patients

scholarly journals Risk Assessment of Opioid Misuse in Italian Patients with Chronic Noncancer Pain

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Renata Ferrari ◽  
Genni Duse ◽  
Michela Capraro ◽  
Marco Visentin
Keyword(s):  
Predictive Validity ◽  
Psychological Intervention ◽  
Opioid Therapy ◽  
Self Report ◽  
Opioid Misuse ◽  
Opioid Use ◽  
Chronic Noncancer Pain ◽  
Good Internal Consistency ◽  
Noncancer Pain ◽  
Pain Patients

Objective. Opioid therapy in patients with chronic noncancer pain must be preceded by evaluation of the risk of opioid misuse. The aim of this study was to evaluate the predictive validity of the Italian translation of the Pain Medication Questionnaire (PMQ) and of the Diagnosis Intractability Risk and Efficacy Score (DIRE) in chronic pain patients. Design. 75 chronic noncancer pain patients treated with opioids were enrolled and followed longitudinally. Risk of opioid misuse was evaluated through PMQ, DIRE, and the physician’s clinical evaluation. Pain experience and psychological characteristics were assessed through specific self-report instruments. At follow-ups, pain intensity, aberrant drug behaviors, and presence of the prescribed opioid and of illegal substances in urine were also checked. Results. PMQ demonstrated good internal consistency (Cronbach’s α=0.77) and test-retest reliability (r=0.86). Significant correlations were found between higher PMQ scores and the number of aberrant drug behaviors detected at 2-, 4-, and 6-month follow-ups (P<0.01). Also the DIRE demonstrated good predictive validity. Conclusions. The results obtained with specific tools are more reliable than the clinician’s evaluation alone in predicting the risk of opioid misuse; regular monitoring and psychological intervention will contribute to improving compliance and outcome of long-term opioid use.

scholarly journals Treatment of chronic noncancer pain in patients on opioid therapy in primary care: A retrospective cohort study

2019 ◽  
Vol 153 (1) ◽  
pp. 52-58
Author(s):  
Arden R. Barry ◽  
Chantal E. Chris
Keyword(s):  
Primary Care ◽  
Cohort Study ◽  
Back Pain ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Opioid Therapy ◽  
Opioid Agonist ◽  
Chronic Noncancer Pain ◽  
Opioid Dose ◽  
Noncancer Pain

Background: This study sought to characterize the real-world treatment of chronic noncancer pain (CNCP) in patients on opioid therapy in primary care. Methods: A retrospective cohort study from 2014-18 was conducted at a multidisciplinary primary care clinic in Chilliwack, British Columbia. Included were adults on daily opioid therapy for CNCP. Patients receiving palliative care or ≤1 visit were excluded. Outcomes of interest included use of opioid/nonopioid pharmacotherapy, number/frequency of visits and proportion of patients able to reduce/discontinue opioid therapy. Results: Seventy patients (mean age 53 years, 53% male, 51% back pain) were included. Median follow-up was 6 visits over 12 months. Sixty-two patients (89%) reduced their opioid dose, 6 patients had no change and 2 patients required a dose increase. Mean opioid dose was reduced from 183 to 70 mg morphine equivalents daily. Twenty-four patients (34%) discontinued opioid therapy, 6 patients (9%) transitioned to opioid agonist therapy and 6 patients (9%) breached their opioid treatment agreement. Nonopioid pharmacotherapy included nonsteroidal anti-inflammatory drugs (64%), gabapentinoids (63%), tricyclic antidepressants (56%) and nabilone (51%). Discussion: Over half of patients were no longer on opioid therapy by the end of the study. Most patients had a disorder (e.g., back pain) for which opioids are generally not recommended. Overall mean opioid dose was reduced from baseline by approximately 60% over 1 year. Lack of access to specialized pain treatments may have accounted for high nonopioid pharmacotherapy usage. Conclusions: This study demonstrates that treatment of CNCP and opioid tapering can successfully be achieved in a primary care setting. Can Pharm J (Ott) 2020;153:xx-xx.

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