Antioxidant activity and antifungal fractional inhibitory concentration indices of zinc oxide nanoparticles in combination with carbendazim, mancozeb, and thiram

2019 ◽  
Vol 14 (10) ◽  
pp. 1037-1040
Author(s):  
Pragati Jamdagni ◽  
J.S. Rana ◽  
Poonam Khatri
2017 ◽  
Vol 9 (5) ◽  
pp. 116 ◽  
Author(s):  
Khoushika Raajshree R. ◽  
Brindha Durairaj

Objective: The present study was designed to evaluate the antioxidant and antityrosinase properties of zinc oxide nanoparticles (ZnO-NPs) synthesized from brown seaweed Turbinaria conoides.Methods: Zinc Oxide Nanoparticles were synthesized from the hydroethanolic extract of Turbinaria conoides. Ultraviolet-Visible Spectrophotometric analysis was performed to confirm the formation of ZnO-NPs. Size, morphology and elemental composition of ZnO-NPs were analysed using SEM-EDAX. The antioxidant activity of the synthesized zinc oxide nanoparticles was investigated by total antioxidant capacity (phosphomolybdenum method), reducing power assay and ferric reducing antioxidant power assay (FRAP). Anti tyrosinase activity was assessed to validate the skin whitening ability of the ZnO-NPs. Results: The antioxidant activity of ZnO-NPs synthesized from hydroethanolic extract of Turbinaria conoides was maximum when compared with that of the hydroethanolic algal extract. The antityrosinase activity of ZnO-NPs was found to be maximum with 75% tyrosinase inhibition when compared to hydroethanolic algal extract which had 56% inhibition at 250μg/ml concentration.Conclusion: Overall our study provides a firm evidence to support that antityrosinase and antioxidant activities are exhibited by ZnO-NPs synthesized from hydroethanolic extract of Turbinaria conoides and it might be used as an antioxidant and as a source of skin whitening agent in cosmetics.


2020 ◽  
Vol 26 (6) ◽  
pp. 200454-0
Author(s):  
Sabaoon Shamshad ◽  
Jamshaid Rashid ◽  
Ihsan-ul-haq ◽  
Naseem Iqbal ◽  
Saif Ullah Awan

Multidrug resistance of bacteria is an emerging human health hazard and warrants development of novel antibacterial agents with more effective mode of action. Here, zinc oxide and silver nanomaterials were prepared using Ficus palmata Forssk leaf extract with efficient antibacterial activity. SEM coupled with EDS confirmed the spherical symmetry with average particle diameter 50 to 65 nm while the XRD confirmed crystalline face centered cubic structure of silver and hexagonal crystallize phase of zinc oxide nanoparticles. Antibacterial activity was evaluated for 8 pathogenic bacterial strains including 3 drug resistant pathogenic strains. The nanoparticles showed enhanced growth inhibition for resistant strains in comparison with the broad-spectrum antibiotics i.e. roxithromycin and cefixime. Minimum inhibitory concentration in μg.mL<sup>-1</sup> of silver nanoparticles was found to be as low as 33.3 for resistant Streptococcus haemolyticus; 11.1 for Staphylococcus aureus and E Coli; and 3.7 μg.mL<sup>-1</sup> for resistant Pseudomonas aeruginosa. Similarly, the minimum inhibitory concentration of zinc oxide nanoparticles was found to be 100 μg.mL<sup>-1</sup> against resistant Streptococcus haemolyticus and Staphylococcus aureus; 11.1 μg.mL<sup>-1</sup> for resistant Pseudomonas aeruginosa; and 3.7 μg.mL<sup>-1</sup> against resistant E coli. Ficus palmata Forssk leaf extracts can be explored effectively for synthesizing active antibacterial nanomaterials as a non-toxic and environmentally benign synthesis route.


2020 ◽  
Vol 11 (3) ◽  
pp. 4690-4694
Author(s):  
Tahoora Taskeen. L ◽  
Hannah R ◽  
Rajeshkumar S

To determine the free radical scavenging activity of fruit formulation mediated zinc oxide nanoparticle. Zinc oxide nanoparticles are widely known for their antimicrobial agent, anti-diabetic, anti-inflammatory, wound healing, antioxidant and optic properties. Oxidative degradation of lipids, proteins, food and cosmetics involves a radical-chain reaction with release of free radicals. These free radicals are extremely reactive and can even attack relatively stable molecules like the DNA bases. With a recent rise in diseases associated with increased oxidative stress, a good antioxidant seems to be the need of the hour. Synthesis of zinc oxide nanoparticles using Punica granatum and Elettaria cardamomum extract. Characterisation of the nanoparticles using UV–Visible spectroscopy and Scanning electron microscope. It is followed by the DPPH radical scavenging assay to determine the antioxidant activity. With an increase in the concentration of zinc oxide nanoparticles, there was an increase in the percentage of inhibition. When compared to the standard, the zinc oxide nanoparticles showed increased antioxidant activity even in small concentrations. Punica granatum and Elettaria cardamomum mediated Zinc oxide nanoparticles showed considerable antioxidant property even in small quantity when compared with standard vitamin C. Further studies need to be carried out to check for its potency as a prophylactic agent.


2020 ◽  
Vol 27 (1) ◽  
pp. 102-110
Author(s):  
Maryam Kokabi ◽  
Samad Nejad Ebrahimi

Background: Green synthesized nanoparticles (NPs) from agricultural wastes is an area of great interest due to it is eco-friendly and profitable. Zinc oxide is an inorganic UV-filter commonly used as UV-blocker in a different industry. Methods: Zinc oxide nanoparticles (ZnO NPs) were successfully biosynthesized using Zn(NO3)2 as a substrate by polyphenol enriched fraction (PEF) of pomegranate peel. The biological activity of ZnO NPs was evaluated using MBC and MIC tests for antibacterial and DPPH assay for antioxidant potential. Sunscreen potential of NPs was determined after applying them in water-in-oil emulsions. Results: UV-Vis and FT-IR spectroscopy techniques confirmed the formation of ZnO NPs. FE-SEM characterized the morphology and purity of the biosynthesized NPs with EDAX and XRD data. The average crystalline size of ZnO NPs was found to be 22 nm. FT-IR spectroscopy revealed the role of phenolic compounds in the formation and stability of ZnO NPs. The antibacterial activity of PEF and its biosynthesized ZnO was evaluated against Staphylococcus aureus and Escherichia coli. The prepared NPs showed a higher antibacterial effect than the commercial ZnO NPs. Interestingly, the antioxidant activity was also detected for obtained NPs. The PEF powder also exhibited higher antibacterial and antioxidant activity than the standards. Furthermore, the in vitro sun protection factors were estimated after applying NPs in water-in-oil emulsions. Conclusion: This study highlighted the possibility of using PEF of pomegranate peel for the biosynthesis of ZnO NPs as well as applying its NPs in sunscreens to achieve a safe alternative to harmful chemical UV-filters commonly used in cosmetics.


2017 ◽  
Vol 23 (12) ◽  
pp. 12502-12505
Author(s):  
Erindyah Retno Wikantyasning ◽  
Muhammad Da’i ◽  
Agung Beny Santosa ◽  
Devy Anwar Zhelsiana

2020 ◽  
Vol 11 (3) ◽  
pp. 4372-4377
Author(s):  
Aparna J ◽  
Rajeshkumar S

The main aim of this study was to employ Maranta arundinacea root extract in the synthesis of Zinc oxide nanoparticles and check the antioxidant activity and cytotoxic effect. The use of nanotechnology in medicine especially for drug delivery is shown to have numerous benefits. Nanoparticles are being used to lessen toxicity and facet results that capsules may additionally impose on the patient. The zinc oxide nanoparticles synthesized using different plant extract used for many biomedical applications such as anticancer activity, antibacterial activity, antioxidant activity, antifungal activity and many more applications used in medicine ( Diagnosis and drug) Plant mediated organic synthesis of nanoparticles has been gaining importance because of its simplicity and eco friendliness. Maranta arundinacea mediated Zinc oxide nanoparticles were initially synthesised and characterised by UV-Visible spectrophotometer and TEM. Further the Maranta arundinacea mediated ZnoNPs were subjected to DPPH assay to determine the antioxidant activity. Maranta arundinacea mediated ZnoNPs were biosynthesised with ease and showed good antioxidant and cytotoxic activity . This study concludes that Maranta arundinacea mediated ZnoNPs nanoparticles have the potential to be used as an effective antioxidant. Hence, it may be employed in large scale production and may be used in many medicinal applications where there is a need for antioxidant.


2019 ◽  
Vol 8 (4S2) ◽  
pp. 1003-1006

Zinc oxide nanoparticles find its versatile application in medicine and industry when compared with other metal nanoparticles. The present study focuses on biogenic synthesis of Zinc Oxide nanoparticles (ZnONPs) using lemon juice extract. Lemon juice extracts contains natural alkaloids and flavonoids which acts as reducing agent for the synthesis of nanoparticles. The synthesized zinc oxide nanoparticle is characterized by Scanning Electron Microscopy (SEM) and FTIR. FTIR results showed the presence of functional groups which represents ZnONPs and reducing groups responsible for the reduction. The SEM observation reveals the synthesized ZnONPs are cube shaped. The obtained nanoparticle was further studied for toxicity using zebrafish embryos. Toxicity results suggested that the toxicity is dose dependent. Malformations in the embryos such as yolk sac edema and twisted tail were seen in higher concentrations. The antioxidant activity of the synthesized ZnONPs was carried out using DPPH assay. Results implied that the antioxidant activity was also concentration dependent.


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