170 Treatment of 25-OH Vitamin D Deficiency in Patients with Moderate Chronic Kidney Disease Reduces Cardiovascular Events

2011 ◽  
Vol 57 (4) ◽  
pp. B59
Author(s):  
Anton Lishmanov ◽  
Smrita Dorairajan ◽  
Youngju Pak ◽  
Kunal Chaudhary ◽  
Anand Chockalingam
Keyword(s):  
Chronic Kidney Disease ◽  
Vitamin D ◽  
Kidney Disease ◽  
Vitamin D Deficiency ◽  
Cardiovascular Events ◽  
25 Oh Vitamin D ◽  
Moderate Chronic Kidney Disease

scholarly journals Insulin Resistance and Vitamin D Deficiency in Patients With Chronic Kidney Disease Stage 2-3

2011 ◽  
pp. 149-155 ◽  
Author(s):  
K. ŠTEFÍKOVÁ ◽  
V. SPUSTOVÁ ◽  
Z. KRIVOŠÍKOVÁ ◽  
A. OKŠA ◽  
K. GAZDÍKOVÁ ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Chronic Kidney Disease ◽  
Vitamin D ◽  
Insulin Sensitivity ◽  
Kidney Disease ◽  
Vitamin D Deficiency ◽  
Chronic Kidney Disease Stage ◽  
Vitamin D Insufficiency ◽  
Disease Stage ◽  
25 Oh Vitamin D

Vitamin D status and the relationship between serum 25(OH) vitamin D concentrations and the components of insulin resistance were examined in 120 patients with chronic kidney disease stage 2 and 3. Insulin sensitivity/resistance was calculated by the quantitative insulin sensitivity check index (QUICKI). In this analysis, the prevalence of insulin resistance was 42 %. Only 17 % of patients had serum 25(OH) vitamin D concentration in the recommended range (≥30 ng/ml), 42 % suffered from vitamin D insufficiency and 41 % had moderate vitamin D deficiency. Insulin resistance significantly correlated with serum 25(OH)D and 1,25(OH)2D concentrations, renal function and protein excretion rate. Our results support the increasing evidence that vitamin D deficiency may be one of the factors participating in the development of insulin resistance already in the early stages of chronic kidney disease.

scholarly journals Prevalence of Decreased Vitamin D Levels is High among Veterans with Diabetes and/or CKD

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Subhashini Yaturu ◽  
Jared Davis
Keyword(s):  
Chronic Kidney Disease ◽  
Vitamin D ◽  
Kidney Disease ◽  
Vitamin D Deficiency ◽  
Vitamin D Insufficiency ◽  
Record System ◽  
Vitamin D Levels ◽  
History Of ◽  
Computerized Patient Record ◽  
25 Oh Vitamin D

Objective. Vitamin D deficiency is associated with a variety of skeletal and extraskeletal problems. The aim of this study was to evaluate the prevalence of vitamin D deficiency among veterans in sunny Louisiana. Methods. Using the VA computerized patient record system, we searched for all 25 (OH) Vitamin D and 1, 25 (OH) vitamin D levels that were measured between 2007 and 2009. The information collected for each patient included age, body mass index, creatinine, history of diabetes and hypertension, and levels of vitamin D and PTH. We determined the number of individuals who were vitamin D insufficient and deficient. Results. Among 2990 studies evaluated, the mean concentration of 25 (OH) D was  ng/mL, and that of 1, 25 (OH) vitamin D was  ng/mL. Among them, only 695 subjects (23%) had normal values, while 889 (30%) had insufficiency, and 1405 (47%) had deficiency. Subjects with diabetes (1041) had significantly () lower levels (21 and 25 ng/mL) of both 25 (OH) and 1,25 (OH) vitamin D compared to subjects without diabetes (23 and 32 ng/mL). Similarly, subjects with chronic kidney disease (1128) had much lower vitamin D levels than subjects without CKD. Among subjects with diabetes, those with chronic kidney disease (512) had much lower levels of both 25 (OH) and 1,25 (OH) vitamin D than with those with normal creatinine levels. Conclusions. We conclude that vitamin D insufficiency and deficiency is highly prevalent in veterans, more so among subjects with diabetes and/or CKD.

scholarly journals Cystatin C, Vitamin D and Thyroid Function Test Profile in Chronic Kidney Disease Patients

Diseases ◽  
2021 ◽  
Vol 9 (1) ◽  
pp. 5
Author(s):  
Marlene Tapper ◽  
Donovan A. McGrowder ◽  
Lowell Dilworth ◽  
Adedamola Soyibo
Keyword(s):  
Chronic Kidney Disease ◽  
Vitamin D ◽  
Cardiovascular Diseases ◽  
Kidney Disease ◽  
Vitamin D Deficiency ◽  
Cystatin C ◽  
Thyroid Dysfunction ◽  
Serum Cystatin C ◽  
Serum Cystatin ◽  
25 Oh Vitamin D

Background: The progression of chronic kidney disease (CKD) is concomitant with complications, including thyroid dysfunction, dyslipidemia and cardiovascular diseases. The aim of this study is to determine serum cystatin C levels, and the prevalence of vitamin D deficiency and thyroid dysfunction in CKD patients. Methods: A cross-sectional study was conducted involving 140 CKD patients (stages 1–5) that were referred to a renal clinic. Demographic data was collected and thyroid function tests, serum 25-OH-vitamin D, cystatin C levels, and routine biochemistry tests were determined using cobas 6000 analyzer. Results: 129 (92.1%) of CKD patients had elevated serum cystatin C levels and there was a stepwise increase from stage 1–5. Overt hypothyroidism was present in one patient and nine had subclinical hypothyroidism. There was a stepwise reduction in serum 25-OH-vitamin D levels from stage 2–5, 31 (22.1%) had vitamin D insufficiency and 31 (22.1%) presented with deficiency. Conclusions: 25-OH-vitamin D deficiency and thyroid disorders are exhibited in chronic kidney disease patients and the severity of the former rises with disease progression, as indicated by elevated cystatin C levels. Routine screening and timely intervention is recommended so as to reduce the risk of cardiovascular diseases.

scholarly journals Vitamin D Deficiency Aggravates the Renal Features of Moderate Chronic Kidney Disease in 5/6 Nephrectomized Rats

2018 ◽  
Vol 5 ◽  
Author(s):  
Ana Carolina de Bragança ◽  
Daniele Canale ◽  
Janaína Garcia Gonçalves ◽  
Maria Heloisa Massola Shimizu ◽  
Antonio Carlos Seguro ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Vitamin D ◽  
Kidney Disease ◽  
Vitamin D Deficiency ◽  
Moderate Chronic Kidney Disease

scholarly journals Clinicians should be more prone to examine children with chronic kidney disease in terms of vitamin D deficiency

2013 ◽  
Vol 33 (2) ◽  
pp. 201-201
Author(s):  
Sevket Balta ◽  
Mustafa Cakar ◽  
Seref Demirbas ◽  
Sait Demirkol
Keyword(s):  
Chronic Kidney Disease ◽  
Vitamin D ◽  
Kidney Disease ◽  
Vitamin D Deficiency
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