scholarly journals Added Value of Fetal MRI in the Evaluation of Fetal Anomalies of the Corpus Callosum: A Retrospective Analysis of 78 Cases

2018 ◽  
Vol 39 (05) ◽  
pp. 513-525
Author(s):  
Mirra Manevich-Mazor ◽  
Alina Weissmann-Brenner ◽  
Omer Bar Yosef ◽  
Chen Hoffmann ◽  
Roei Mazor ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Retrospective Analysis ◽  
Fetal Mri ◽  
Added Value ◽  
Fetal Anomalies

Added Value of Fetal MRI in the Evaluation of Fetal Anomalies of the Corpus Callosum: A Retrospective Analysis of 78 Cases

2018 ◽  
Vol 39 (05) ◽  
pp. 513-525 ◽  
Author(s):  
Mirra Manevich-Mazor ◽  
Alina Weissmann-Brenner ◽  
Omer Bar Yosef ◽  
Chen Hoffmann ◽  
Roei Mazor ◽  
...  
Keyword(s):  
Decision Making ◽  
Corpus Callosum ◽  
Clinical Decision Making ◽  
Brain Mri ◽  
Fetal Brain ◽  
Fetal Mri ◽  
Clinical Decision ◽  
Added Value ◽  
Callosal Agenesis

Abstract Objective To evaluate the added value of fetal MRI to ultrasound in detecting and specifying callosal anomalies, and its impact on clinical decision making. Methods Fetuses with a sonographic diagnosis of an anomalous corpus callosum (CC) who underwent a subsequent fetal brain MRI between 2010 and 2015 were retrospectively evaluated and classified according to the severity of the findings. The findings detected on ultrasound were compared to those detected on MRI. An analysis was performed to assess whether fetal MRI altered the group classification, and thus the management of these pregnancies. Results 78 women were recruited following sonographic diagnoses of either complete or partial callosal agenesis, short, thin or thick CC. Normal MRI studies were obtained inµ19 cases (24 %). Among these, all children available for follow-up received an adequate adaptive score in their Vineland II adaptive behavior scale assessment. Analysis of the concordance between US and MRI demonstrated a substantial level of agreement for complete callosal agenesis (kappa: 0.742), moderate agreement for thin CC (kappa: 0.418) and fair agreement for all other callosal anomalies. Comparison between US and MRI-based mild/severe findings classifications revealed that MRI contributed to a change in the management for 28 fetuses (35.9 %), mostly (25 fetuses, 32.1 %) in favor of pregnancy preservation. Conclusion Fetal MRI effectively detects callosal anomalies and enables satisfactory validation of the presence or absence of callosal anomalies identified by ultrasound and adds valuable data that improves clinical decision making.

scholarly journals OP04.03: Contribution of fetal MRI to prenatal ultrasound for the diagnosis of fetal anomalies

2008 ◽  
Vol 32 (3) ◽  
pp. 321-321
Author(s):  
A. Lembet ◽  
H. Bodur ◽  
B. Selam ◽  
A. Damlacik ◽  
C. Demirel ◽  
...  
Keyword(s):  
Fetal Mri ◽  
Prenatal Ultrasound ◽  
Fetal Anomalies

scholarly journals Fetal MRI vs. fetal ultrasound in the diagnosis of pathologies of the central nervous system

2021 ◽  
Vol 31 (Supplement_2) ◽  
Author(s):  
Inês Pimentel ◽  
João Costa ◽  
Óscar Tavares
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Corpus Callosum ◽  
Fetal Mri ◽  
Fetal Ultrasound ◽  
Fetal Malformations ◽  
Fetal Us ◽  
The Central Nervous System ◽  
Common Group ◽  
Magnetic Resonance Imaging Mri

Abstract Background Malformations of the central nervous system (CNS) constitute the 2nd most common group of fetal pathologies, which can be reflected throughout the patient's life. Fetal ultrasound (US), together with fetal magnetic resonance imaging (MRI) are extremely important techniques for the diagnosis of CNS malformations. The objective of this work was to address fetal US and fetal MRI, as well as the benefits of its use in different CNS pathologies and to ascertain which of the techniques presents better results. Methods For this systematic literature review, a search was conducted using databases such as PubMed® and ScienceDirect®, Google Scholar, b-on digital library, in a 10-year period, 2010 to 2020. 60 references were used, which met the inclusion criteria, namely compliance with the defined timeframe and the theme of the work to be addressed. Results As for the results, fetal US is the first-line technique for fetal evaluation, and its objective is to detect possible fetal malformations early, while fetal MRI complements the information collected through fetal US. When there are cases of isolated ventriculomegaly and complete agenesis of the corpus callosum, fetal US can correctly assess the pathology. When it comes to pathologies such as dysgenesis of the corpus callosum and malformations of the posterior fossa, fetal MRI evaluates more effectively in comparison to fetal US. Conclusions In conclusions, to reduce the number of false positives, the techniques should be used together, thus providing a better diagnosis.

scholarly journals AVID triad: a case report

2020 ◽  
Vol 8 (5) ◽  
pp. 1918
Author(s):  
Manoj M. C. ◽  
Lokesh Kumar T.
Keyword(s):  
Case Report ◽  
Corpus Callosum ◽  
Fetal Mri ◽  
Male Child ◽  
Imaging Findings ◽  
Mri Imaging ◽  
History Of ◽  
Interhemispheric Cyst

Asymmetric ventriculomegaly, interhemispheric cyst and dysgenesis of the corpus callosum (AVID) constitutes a rare imaging triad. Additional findings include subcortical and subependymal heterotopia, polymicrogyria, fused thalami, deficient falx, and hydrocephalus. The knowledge of this triad helps us to diagnose prenatally by sonography and fetal MRI. In this case report authors present MRI Imaging findings in a case of AVID syndrome in a 6year old male child presenting with history of seizures and delayed milestones.

scholarly journals Antenatal diagnosis of alobar holoprosencephaly: a case report

2019 ◽  
Vol 6 (5) ◽  
pp. 2198
Author(s):  
Manjushri Waikar ◽  
Anamika Singh
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Antenatal Diagnosis ◽  
Fetal Mri ◽  
Psychological Trauma ◽  
Vital Role ◽  
Outpatient Department ◽  
Fetal Anomalies ◽  
Medical Termination ◽  
The Brain

 Holoprosencephaly (HPE) is a structural malformation of the brain that results from the complete or incomplete noncleavage of the forebrain/ prosencephalon of the embryo into 2 hemispheres1. We present a case of twenty-five year-old primigravida presented to the Outpatient department of Obstetrics for routine checkup and diagnosed with Alobar holoprosencephaly on 2nd level USG. Fetal MRI was performed and the findings were confirmed. Even though ultrasonography is diagnostic in the detection of fetal anomalies, MRI plays a vital role due to its multiplanar capability and excellent soft tissue resolution. The purpose of publishing this case is to sensitize the clinicians to the classical features of holoprosencephaly on various imaging modalities and to stress the importance of its detection before 20 weeks of gestation so as to allow for legal medical termination and alleviate maternal psychological trauma of bearing a deformed fetus.

scholarly journals OC18.03: Association between brain metabolism by MRI spectroscopy with corpus callosum development and cortical sulcation assessed by fetal MRI at term

2014 ◽  
Vol 44 (S1) ◽  
pp. 42-42
Author(s):  
M. Sanz-Cortes ◽  
G. Egaña-Ugrinovic ◽  
R.V. Simoes ◽  
N. Masoller ◽  
N. Bargallo ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Brain Metabolism ◽  
Fetal Mri

scholarly journals Prenatal Diagnosis of WAGR Syndrome

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Berrin Tezcan ◽  
Philip Rich ◽  
Amarnath Bhide
Keyword(s):  
Prenatal Diagnosis ◽  
Corpus Callosum ◽  
Microarray Analysis ◽  
Genetic Disorder ◽  
Fetal Mri ◽  
Septum Pellucidum ◽  
Chromosomal Microarray Analysis ◽  
Chromosome 11 ◽  
Cavum Septum Pellucidum ◽  
Wagr Syndrome

Wilm’s tumour, aniridia, genitourinary abnormalities, and mental retardation (WAGR) syndrome is a rare genetic disorder with an estimated prevalence of 1 in 500,000 to 1 million. It is a contiguous gene syndrome due to deletion at chromosome 11p13 in a region containing WT1 and PAX6 genes. Children with WAGR syndrome mostly present in the newborn/infancy period with sporadic aniridia. The genotypic defects in WAGR syndrome have been well established. However, antenatal ultrasonographic presentation of this syndrome has never been reported. Prenatal diagnosis of this condition is possible in some cases with careful ultrasound examination of classical and nonclassical manifestations of this syndrome. The key point for this rare diagnosis was the decision to perform chromosomal microarray analysis after antenatal diagnosis of absent corpus callosum and absent cavum septum pellucidum, as this finding mandates search for potentially associated genetic disorders. We report a case of WAGR syndrome diagnosed prenatally at 29-week gestation. The diagnosis of the anomaly was based on two- and three-dimensional ultrasound as well as fetal MRI scan and microarray analysis. The ultrasonographic findings included borderline ventriculomegaly, absent corpus callosum, and absent cavum septum pellucidum. Cytogenetic results from the amniotic fluid confirmed WAGR syndrome. Parental karyotype was normal, with no evidence of copy number change, deletion, or rearrangement of this region of chromosome 11.

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