10.7 Chronic Recurrent Multifocal Osteomyelitis and SAPHO Syndrome

2016 ◽  
Keyword(s):  
Chronic Recurrent Multifocal Osteomyelitis ◽  
Sapho Syndrome ◽  
Multifocal Osteomyelitis

scholarly journals Non-bacterial osteitis: Chronic Recurrent Multifocal Osteomyelitis or pediatric SAPHO?

2020 ◽  
pp. 26-28
Keyword(s):  
Innate Immunity ◽  
Clinical Features ◽  
Bone Disease ◽  
Bone Pain ◽  
Clinical Presentation ◽  
Chronic Recurrent Multifocal Osteomyelitis ◽  
Sapho Syndrome ◽  
Imaging Features ◽  
Common Clinical Presentation ◽  
Multifocal Osteomyelitis

Chronic Recurrent Multifocal Osteomyelitis (CRMO) and SAPHO syndrome represent the group of autoinflammatory bone disease responsible for recurrent non-bacterial osteitis (NBO). both are considered as defects of innate immunity. The most common clinical presentation is recurrent episodes of bone pain with or without fever.The clinical and imaging features are non-specific.This usually leads to late and confusing diagnosis. We hereby report a case of CRMO in a 12-year-old patient. The aim is to highlight the confusing overlap of clinical features between CRMO and SAPHO syndromes. Keywords: multifocal osteomyelitis, non-bacterial osteitis, SAPHO, bone pain.

THE "SAPHO" SYNDROME: A CASE REPORT OF A PATIENT WITH AN ACCIDENTAL FINDING OF HYPEROSTOSIS IN PLAIN X-RAYS OF THORAX

2008 ◽  
Vol 11 (01) ◽  
pp. 29-35
Author(s):  
M. Pyrgioti ◽  
E. Mahaira ◽  
G. Papagiannakis ◽  
A. Syrou ◽  
I. H. Alexandris ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Health Status ◽  
Bone Tissue ◽  
Laboratory Tests ◽  
Chronic Recurrent Multifocal Osteomyelitis ◽  
Sapho Syndrome ◽  
X Rays ◽  
Multifocal Osteomyelitis ◽  
Histopathologic Findings

The authors describe the clinical, bone scintigraphy, and histopathologic findings of chronic recurrent multifocal osteomyelitis (CRMO), which is considered to be part of the SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome. Knowledge of this disorder may help in the differential diagnosis of arthritis, and it will help avoid repeated biopsies. We report the case of a 52-year-old man who was admitted to hospital due to an accidental finding in plain X-rays during his first check-up of his health status. He underwent laboratory tests, imaging examinations, and biopsy and histopathologic examinations of bone tissue; and was diagnosed with the SAPHO syndrome (CRMO).

scholarly journals SAPHO syndrome with enthesopathy

2019 ◽  
Vol 12 (1) ◽  
pp. e225929 ◽  
Author(s):  
Chin-Fang Su ◽  
Yu-Chuan Shen ◽  
Hsien-Tzung Liao ◽  
Chang-Youh Tsai
Keyword(s):  
Clinical Manifestations ◽  
Chronic Recurrent Multifocal Osteomyelitis ◽  
Sapho Syndrome ◽  
Asian Woman ◽  
Imaging Features ◽  
Middle Aged ◽  
Multifocal Osteomyelitis

Synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome was first described as chronic recurrent multifocal osteomyelitis. Because of its rarity, a thorough description of its clinical manifestations is lacking. Herein, we describe the clinical manifestations and imaging features, especially the enthesopathy in bilateral Achilles tendons, of a middle-aged Asian woman with SAPHO syndrome, who improved after diclofenac treatment.

Chronic recurrent multifocal osteomyelitis in children: a new, MRI-based method of quantifying inflammation in the bone

2015 ◽  
Author(s):  
Dionysios Alexandrou ◽  
Benjamin Jacobs ◽  
O'Donnell Paul ◽  
Rikin Hargunani ◽  
Ananya Guha ◽  
...  
Keyword(s):  
Chronic Recurrent Multifocal Osteomyelitis ◽  
Multifocal Osteomyelitis
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