A Population-based Study on Trends in the Mode of Delivery Subsequent to Stillbirth, Infant Mortality and Severe Infant Malformations in the State of Hesse, Germany between 1990 and 2012

Abstract Introduction The study aims to assess the changes in prevalence and mortality of gastroschisis, and to identify associated anomalies. Materials and Methods It is a population-based nationwide study. All gastroschisis cases were identified in the Finnish Register of Congenital Malformations and the Care Register for Health Care from 1993 to 2014 including live births, stillbirths, and terminations of pregnancy due to fetal anomalies. Associated anomalies were recorded, and analyzed, and prevalence and infant mortality were calculated. Results There were 320 cases of gastroschisis; 235 (73%) live births, 16 (5%) stillbirths, and 69 (22%) terminations of pregnancy. Live birth prevalence of gastroschisis in Finland was lower than generally reported (1.73 in 10,000). However, due to relatively high rates of abortion, our total prevalence of 2.57/10,000 was similar with other reports. The most common risk factor was young maternal age. Babies with gastroschisis were born prematurely, on average on the 36th week and most are delivered by caesarean section. There was a significant increasing trend in live birth prevalence (p = 0.0018). Overall infant mortality was 7.7% (18/235), 7.2% (16/222) in simple gastroschisis and 15% (2/13) in complex gastroschisis. Associated anomalies were rare both in aborted fetuses and neonates, and there was only one case with a chromosomal abnormality. Conclusion Gastroschisis is usually an isolated anomaly with increasing birth prevalence and excellent survival rates. Regardless of the good prognosis, the abortion rates in Finland are higher than previously reported, and we hypothesize this to be due to lack of appropriate antenatal counselling.

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Birth Incidence of Cerebral Palsy in Tripoli, Libya: A Population-Based Study

Khalij-Libya Journal of Dental and Medical Research ◽

10.47705/kjdmr.210101 ◽

2020 ◽

pp. 1-5

Author(s):

Ahmed Atia ◽

Aya Abogrein ◽

Maram Alssoghaiar ◽

Mawada Akroush ◽

Mawada Alsagheer

Keyword(s):

Cerebral Palsy ◽

Mode Of Delivery ◽

Congenital Toxoplasmosis ◽

Birth Asphyxia ◽

Neonatal Infection ◽

Population Based ◽

University Hospital ◽

Cross Sectional ◽

Population Based Study ◽

Background Population

Background: Population-based data in Libya on prevalence of cerebral palsy are limited. This study aimed to assess trends in cerebral palsy among infancy or premature attending pediatric hospitals in Tripoli city, Libya. Methods: In this population-based study, a cross-sectional method was used to screen for cerebral palsy at the department of pediatrics in both Tripoli University Hospital, and Tripoli Pediatric Hospital during the period from march to December 2019. Specialist physicians confirmed the diagnosis, obtained family history, and determined the subtype and main causes. Results: Out of 200 suspected patients, 64 of them were diagnosed with cerebral palsy. Incidence rate was 32%. Male children (n=33, 51.6%) were more affected than female (n=31, 48.4%). Regarding the mode of delivery, 34(53.1%) of patients were delivered normally by vaginal delivery, while 30(46.9%) of cases delivered by caesarian section. There were 9(14.1%) of cases preterm birth, whereas, most of the cases were full term 55(85.9%). Birth asphyxia was reported in 34 (53.1%) of cases. A total of 17(26.6%) of cases had genetic cause, 8(12.5%) of cases had history of neonatal infection (e.g. meningitis, congenital toxoplasmosis, pneumonia, sepsis, encephalitis), and 5(7.8%) of cases had other disorders including hyperthermia and asphyxia at late age. Conclusion: Given enhancements in neonatal survival, evidence of stability of cerebral palsy prevalence is encouraging. The persistence of higher cerebral palsy prevalence among children in Libya over time warrants further investigation.

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