Green Synthesis of Pyrido[2,1-a]isoquinolines and Pyrido[1,2-a]quinolines by Using ZnO Nanoparticles

Synlett ◽  
2017 ◽  
Vol 29 (04) ◽  
pp. 493-496 ◽  
Author(s):  
Fatemeh Sheikholeslami-Farahani ◽  
Maryam Ghazvini ◽  
Somayeh Soleimani-Amiri ◽  
Masoomeh Salimifard ◽  
Rezvaneh Rostamian
Keyword(s):  
Green Synthesis ◽  
Zno Nanoparticles ◽  
Room Temperature ◽  
Solvent Free ◽  
Quinoline Derivatives ◽  
Zno Nps ◽  
Efficient Catalyst ◽  
Solvent Free Conditions ◽  
Acetylenic Compounds

Pyrido[2,1-a]isoquinoline and pyrido[1,2-a]quinoline derivatives have been produced in good yields by the reaction of isoquinoline or quinoline, activated acetylenic compounds, α-halo ketones, and triphenylphosphine in the presence of ZnO nanoparticles (NPs) as an efficient catalyst under solvent-free conditions at room temperature. The reaction workup is easy, and the products can be readily separated from the reaction mixture. ZnO NPs markedly improved the yield of the product. The catalyst showed significant reusable activity.

Preparation and Characterization of a Novel Room Temperature Dicationic Ionic Liquid and its Application in the Synthesis of Xanthenediones Under Solvent-Free Conditions

2018 ◽  
Vol 21 (8) ◽  
pp. 602-608 ◽  
Author(s):  
Zainab Ehsani-Nasab ◽  
Ali Ezabadi
Keyword(s):  
Ionic Liquid ◽  
Room Temperature ◽  
Reaction Times ◽  
Significant Loss ◽  
Solvent Free ◽  
Acidity Function ◽  
Efficient Catalyst ◽  
Solvent Free Conditions ◽  
Hammett Acidity Function ◽  
Dicationic Ionic Liquid

Aim and Objective: In the present work, 1, 1’-sulfinyldiethylammonium bis (hydrogen sulfate) as a novel room temperature dicationic ionic liquid was synthesized and used as a catalyst for xanthenediones synthesis. Material and Method: The dicationic ionic liquid has been synthesized using ethylamine and thionyl chloride as precursors. Then, by the reaction of [(EtNH2)2SO]Cl2 with H2SO4, [(EtNH2)2SO][HSO4]2 was prepared and after that, it was characterized by FT-IR, 1H NMR, 13C NMR as well as Hammett acidity function. This dicationic ionic liquid was used as a catalyst for the synthesis of xanthenediones via condensation of structurally diverse aldehydes and dimedone under solvent-free conditions. The progress of the reaction was monitored by thin layer chromatography (ethyl acetate/n-hexane = 3/7). Results: An efficient solvent-free method for the synthesis of xanthenediones has been developed in the presence of [(EtNH2)2SO][HSO4]2 as a powerful catalyst with high to excellent yields, and short reaction times. Additionally, recycling studies have demonstrated that the dicationic ionic liquid can be readily recovered and reused at least four times without significant loss of its catalytic activity. Conclusion: This new dicationic ionic liquid can act as a highly efficient catalyst for xanthenediones synthesis under solvent-free conditions.

scholarly journals A convenient synthesis of N-tert-butyl amides by the reaction of di-tert-butyl dicarbonate and nitriles catalyzed by Cu(OTf)2

2020 ◽  
Vol 44 (9-10) ◽  
pp. 602-608
Author(s):  
Wanfeng Yang ◽  
Chengliang Feng ◽  
Yuqi Tang ◽  
Min Ji ◽  
Junqing Chen
Keyword(s):  
Room Temperature ◽  
Solvent Free ◽  
Ritter Reaction ◽  
Alkyl Aryl ◽  
Efficient Catalyst ◽  
Tert Butyl ◽  
Convenient Synthesis ◽  
Solvent Free Conditions

The utility of Cu(OTf)2 as the catalyst for the synthesis of a series of N- tert-butyl amides in excellent isolated yields via the reaction of nitriles (alkyl, aryl, benzyl, and furyl nitriles) with di- tert-butyl dicarbonate is described. Cu(OTf)2 is a highly stable and efficient catalyst for the present Ritter reaction under solvent-free conditions at room temperature.

scholarly journals K2CO3: A Mild and Efficient Catalyst for the Synthesis of Pyran Annulated Heterocyclic Systems by Grinding Method Under Solvent-Free Conditions

2017 ◽  
Vol 25 (2) ◽  
pp. 163-178 ◽  
Author(s):  
Reza Heydari ◽  
Rohollah Rahimi ◽  
Mehrnoosh Kangani ◽  
Afshin Yazdani-Elah-Abadi ◽  
Mojtaba Lashkari
Keyword(s):  
Room Temperature ◽  
Reaction Times ◽  
Aromatic Aldehydes ◽  
Solvent Free ◽  
Synthetic Methods ◽  
One Pot ◽  
Efficient Catalyst ◽  
Grinding Method ◽  
Solvent Free Conditions ◽  
The One

Abstract The potassium carbonate was applied as a green and efficient catalyst for the one-pot synthesis of pyran annulated heterocyclic systems, via the condensation between aromatic aldehydes, malononitrile and dimedone/1-naphtole by a grinding method at room temperature and solvent-free conditions. Short reaction times, environmentally friendly procedure and excellent yields are the main advantages of this procedure which makes it more economic than other environmentally synthetic methods.

Solvent-free synthesis of β-enamino ketones and esters catalysed by recyclable iron(III) triflate

2014 ◽  
Vol 68 (8) ◽  
Author(s):  
Cheng-Liang Feng ◽  
Ning-Ning Chu ◽  
Shu-Guang Zhang ◽  
Jin Cai ◽  
Jun-Qing Chen ◽  
...  
Keyword(s):  
Green Synthesis ◽  
Reaction System ◽  
Solvent Free ◽  
Primary Amines ◽  
Efficient Catalyst ◽  
Enamino Ketones ◽  
Minimal Loss ◽  
Solvent Free Conditions ◽  
High Yields ◽  
Solvent Free Synthesis

AbstractA novel application of highly stable Fe(OTf)3 as an efficient catalyst for the synthesis of a variety of β-enamino ketones and esters under solvent-free conditions is described. Notably, this protocol of a “green synthesis”, which produced β-enamino ketones and esters by the reaction of a variety of β-dicarbonyl compounds and primary amines, exhibits attractive properties including high yields, short reaction periods, lower loading of catalyst and chemo- and regio-selectivity. In addition, the catalyst was easily recovered from the reaction system and readily reused with minimal loss of activity.

Green synthesis of α-aminophosphonates using ZnO nanoparticles as an efficient catalyst

2018 ◽  
Vol 73 (3-4) ◽  
pp. 179-184 ◽  
Author(s):  
Elham Ezzatzadeh
Keyword(s):  
Natural Products ◽  
Green Synthesis ◽  
Zno Nanoparticles ◽  
Room Temperature ◽  
Primary Amines ◽  
Green Solvent ◽  
Efficient Catalyst ◽  
Trialkyl Phosphites

AbstractSynthesis ofα-aminophosphonate derivatives via the Kabachnik–Fields reaction is described using 1-(6-hydroxy-2-isopropenyl-1-benzofuran-yl)-1-ethanone, extracted from rhizomes ofPetasites hybridus, primary amines and trialkyl phosphites in the presence of ZnO nanoparticles in water at room temperature. This procedure has advantages such as using natural products as precursors, employing water as a green solvent, good yields and easy separation of products.

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