scholarly journals Cervical Intramedullary Schwannoma with Syrinx: Case Report and Review of the Literature

2017 ◽  
Vol 07 (03) ◽  
pp. 239-248
Author(s):  
Abdulaziz AlQarni ◽  
A. AlArifi ◽  
Ali Alassiri ◽  
Amjed Kouli ◽  
M. Abbas
Keyword(s):  
Spinal Cord ◽  
Cervical Spinal Cord ◽  
Lower Limbs ◽  
Nerve Sheath Tumor ◽  
Resonance Imaging ◽  
Spinal Cord Tumors ◽  
Nerve Sheath ◽  
Spindle Cells ◽  
The Right ◽  
Intramedullary Schwannoma

AbstractSchwannoma is a nerve sheath tumor originating from the Schwann cell. It is benign in nature and it arises from anywhere where Schwann cells can be found. It is rarely found in the parenchyma of the spinal cord. Intramedullary schwannomas (or neurilemmomas) without evidence of neurofibromatosis are rare spinal cord tumors. Intramedullary schwannoma was first reported in 1932 by Penfield. Our patient presented with neck pain, gradually worsening, weakness in the right upper and lower limbs, numbness in both shoulders, and a decrease in the grasping strength of both hands over a 4-year period. A magnetic resonance imaging of the spine showed a heterogeneously enhancing mass in the cervical spinal cord extending from the C2 to T1 levels with associated hemorrhagic changes. Histologically, the tumor was found to be composed of bland spindle cells with blunt-ended and sometimes wavy nuclei admixed with hyalinized vasculature. Surrounding reactive spinal cord parenchyma with frequent Rosenthal fibers was also observed. Focal Verocay bodies were evident, and with immunohistochemistry, there was diffuse and strong positivity for S100, which is confirmatory for the diagnosis of schwannoma. We report a case of cervical intramedullary schwannoma presented with syringobulbia in a young adult.

Malignant intracerebral nerve sheath tumor with intratumoral calcification

2000 ◽  
Vol 92 (2) ◽  
pp. 338-341 ◽  
Author(s):  
Minoru Tanaka ◽  
Soichiro Shibui ◽  
Kazuhiro Nomura ◽  
Yukihiro Nakanishi ◽  
Tadashi Hasegawa ◽  
...  
Keyword(s):  
Nerve Sheath Tumor ◽  
Pathological Features ◽  
Resonance Imaging ◽  
Content Type ◽  
Nerve Sheath ◽  
First Case ◽  
The Right ◽  
Tomography Scanning ◽  
Considerable Enhancement ◽  
Fine Print

✓ The authors present the clinical, radiological, and pathological features of a malignant intracerebral nerve sheath tumor that occurred in the right parietooccipital lobe of a 4-year-old girl. Computerized tomography scanning and magnetic resonance imaging demonstrated a 5 × 5 × 4—cm multiloculated mass with considerable enhancement of the irregularly shaped septa and clearly calcified areas within the mass. Among five cases reported in the literature, this patient is the youngest and represents the first case in which there is radiological evidence of intratumoral calcification.

scholarly journals Malignant peripheral nerve sheath tumor of the distal phalanx of the fifth toe: a case report

2014 ◽  
Vol 3 (1) ◽  
pp. 204798161351603 ◽  
Author(s):  
Yuki Iwama ◽  
Makoto Kunisada ◽  
Hajimu Goto ◽  
Yoshiharu Ohno ◽  
Junji Yamashita ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Distal Phalanx ◽  
Nerve Sheath Tumor ◽  
Resonance Imaging ◽  
Peripheral Nerve Sheath Tumor ◽  
Histological Features ◽  
Nerve Sheath ◽  
Subcutaneous Tissues ◽  
Fifth Toe ◽  
The Right

Malignant peripheral nerve sheath tumor (MPNST) involving bone is rare. We report a case of MPNST of the fifth toe. The lesion was located in the distal phalanx of the right fifth toe and extended into surrounding subcutaneous tissues. Findings on magnetic resonance imaging and histological features of the case are described and the literature is briefly reviewed.

scholarly journals Neuromyelitis Optica in a Nepalese Man

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Yogesh Subedi ◽  
Utsav Joshi ◽  
Sanjeeb Sudarshan Bhandari ◽  
Ashbina Pokharel ◽  
Ashbita Pokharel
Keyword(s):  
Spinal Cord ◽  
Neuromyelitis Optica ◽  
Immunoglobulin G ◽  
Cervical Spinal Cord ◽  
Immunosuppressive Treatment ◽  
Lower Limbs ◽  
Inflammatory Disorder ◽  
Hyperintense Signal ◽  
Muscle Groups ◽  
The Right

Background. Neuromyelitis optica is a severely disabling inflammatory disorder of the central nervous system of autoimmune etiology that mainly affects the optic nerves and spinal cord. Here, we present a case report detailing a patient with tingling and weakness of right upper and lower limbs who was neuromyelitis optica immunoglobulin G-positive. Case Presentation. A 46-year-old Nepalese man presented to the hospital with a history of tingling and weakness of right upper and lower limbs that developed over a period of two months. Clinical evaluation showed diminished power across all major muscle groups in the right upper and lower limbs. Magnetic resonance imaging of his cervical spine showed T1 iso- to hypointense signal and T2 hyperintense signal in central cervical spinal cord from first to sixth cervical level, probably suggestive of myelitis or demyelination. The patient was immediately started on intravenous methylprednisolone. The diagnosis of neuromyelitis optica was later confirmed with strongly positive neuromyelitis optica immunoglobulin G. Conclusion. In resource limited setting, in the absence of tests for neuromyelitis optica immunoglobulin G, treatment was started and the patient’s condition started to get better. Hence, early initiation of aggressive immunosuppressive treatment is essential in such cases.

scholarly journals Malignant Peripheral Nerve Sheath Tumor with Divergent Mesenchymal Differentiations in a Dog

2003 ◽  
Vol 15 (2) ◽  
pp. 174-178 ◽  
Author(s):  
D.-Y. Kim ◽  
D.-Y. Cho ◽  
D. Y. Kim ◽  
J. Lee ◽  
H. W. Taylor
Keyword(s):  
Electron Microscopy ◽  
Spinal Cord ◽  
Peripheral Nerve ◽  
Cervical Spinal Cord ◽  
Labrador Retriever ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath

A malignant peripheral nerve sheath tumor with divergent osteogenic, myxomatous, and myoblastic differentiations is described in a 10.5-year-old male Labrador Retriever dog. The tumor involved the sixth and seventh cervical spinal cord segments and nerves. The diagnosis was based on the results of histopathology, electron microscopy, and immunohistochemistry.

Surgical resection of subependymoma of the cervical spinal cord

2014 ◽  
Vol 37 (v2supplement) ◽  
pp. Video3 ◽  
Author(s):  
Lee A. Tan ◽  
Manish K. Kasliwal ◽  
Nakhle Mhanna ◽  
Ricardo B. V. Fontes ◽  
Vincent C. Traynelis
Keyword(s):  
Spinal Cord ◽  
Rare Case ◽  
Cervical Spinal Cord ◽  
Conus Medullaris ◽  
Resonance Imaging ◽  
Spinal Cord Tumors ◽  
Gadolinium Enhancement ◽  
Cervicothoracic Junction ◽  
Total Resection ◽  
Thoracic Cord

Subependymomas can rarely occur in the spinal cord, and account for about 2% of symptomatic spinal cord tumors. It most often occurs in the cervical spinal cord, followed by cervicothoracic junction, thoracic cord and conus medullaris. It often has an eccentric location in the spinal cord and lacks gadolinium enhancement on magnetic resonance imaging. We present a rare case of symptomatic subependymoma of the cervical spinal cord, which underwent successful gross total resection. Surgical pearls and nuances are discussed to help surgeons to avoid potential complications.The video can be found here: http://youtu.be/Rsm9KxZX7Yo.

Central neurocytomas of the cervical spinal cord

1994 ◽  
Vol 81 (2) ◽  
pp. 288-293 ◽  
Author(s):  
Stephen B. Tatter ◽  
Lawrence F. Borges ◽  
David N. Louis
Keyword(s):  
Spinal Cord ◽  
Cervical Spinal Cord ◽  
Correct Diagnosis ◽  
Central Neurocytoma ◽  
Neurological Deficits ◽  
Resonance Imaging ◽  
Spinal Cord Tumors ◽  
Intramedullary Spinal Cord ◽  
Content Type ◽  
Fine Print

✓ Central neurocytoma is a neuronal neoplasm that occurs supratentorially in the lateral or third ventricles. The authors report the clinical, neuroradiological, and neuropathological features of two neurocytomas arising in the spinal cord of two men, aged 65 and 49 years. The patients presented with progressive neurological deficits referable to the cervical spinal cord. Magnetic resonance imaging revealed isodense intramedullary spinal cord tumors at the C3–4 level. Both tumors were initially misdiagnosed as gliomas. In Case 1 the correct diagnosis was made after electron microscopy revealed neuronal features. Immunostaining in Case 2 revealed that tumor cells were positive for synaptophysin and negative for glial fibrillary acidic protein, strongly indicating a neuronal tumor. It is suggested that this spinal cord neoplasm be included under the designation “central neurocytoma.”

Cerebral Malignant Nerve Sheath Tumor, Triton Tumor Variant: Case Report

2003 ◽  
Vol 6 (2) ◽  
pp. 168-172 ◽  
Author(s):  
Leticia Bornstein-Quevedo ◽  
Fabiola Peralta-Olvera ◽  
Alfonso Marhx-Bracho ◽  
Rodolfo Rodríguez-Jurado ◽  
Beatriz de Leon-Bojorge
Keyword(s):  
Clinical Evidence ◽  
Immunohistochemical Study ◽  
Nerve Sheath Tumor ◽  
Intraparenchymal Hemorrhage ◽  
Malignant Triton Tumor ◽  
Nerve Sheath ◽  
Spindle Cells ◽  
S 100 ◽  
History Of ◽  
The Right

A case of a cerebral malignant triton tumor in a 3-year-old boy with a 2-month history of frontal headache and no clinical evidence of neurofibromatosis is reported. The computed tomography (CT) scan showed a large, irregular tumor in the right parietooccipital lobe. A partial surgical resection was performed. Histologically, the tumor was highly cellular and consisted of spindle cells with hyperchromatic and pleomorphic nuclei. Focally, neoplastic cells with rhabdomyoblastic features were found. The immunohistochemical study showed that tumor cells were positive for S-100 protein and CD57, and the rhabdomyoblasts expressed desmin, Myo-D1, and myoglobin. During the postoperative period, a massive intraparenchymal hemorrhage was identified and surgical drainage was performed. The patient worsened and died 10 days after the first surgery. Postmortem study was not authorized. Six cases of cerebral malignant nerve sheath tumor have been described; however, primary intraparenchymal malignant triton tumor has not been previously described.

scholarly journals Diffusion tensor magnetic resonance imaging may show abnormalities in the normal-appearing cervical spinal cord from patients with multiple sclerosis

2013 ◽  
Vol 71 (9A) ◽  
pp. 580-583 ◽  
Author(s):  
Fernanda Miraldi ◽  
Fernanda Cristina Rueda Lopes ◽  
Joao Victor Altamiro Costa ◽  
Soniza Vieira Alves-Leon ◽  
Emerson Leandro Gasparetto
Keyword(s):  
Multiple Sclerosis ◽  
Spinal Cord ◽  
Diffusion Tensor ◽  
Cervical Spinal Cord ◽  
Mean Diffusivity ◽  
Resonance Imaging ◽  
Neurologic Disorder ◽  
The Right ◽  
Diffusion Tensor Mr Imaging

Objective This study aims to evaluate “in vivo” the integrity of the normal-appearing spinal cord (NASC) in patients with multiple sclerosis (MS) compared to controls, using diffusion tensor MR imaging. Methods We studied 32 patients with MS and 17 without any neurologic disorder. Fractional anisotropy (FA), axial diffusivity (AD), radial diffusivity (RD) and mean diffusivity (MD) were calculated within regions of interest at C2 and C7 levels in the four columns of the spinal cord. Results At C2, FA value was decreased in MS patients. Besides, RD value was higher in MS than in controls. At C7, MD values were increased in MS. Conclusion The NASC in the right column of the cervical spinal cord showed abnormal FA, RD and MD values, which is possibly related to demyelination, since the FA abnormality was related to the RD and not to the AD.

Malignant Nerve Sheath Tumor of the Right Cerebral Peduncle: Case Report

Neurosurgery ◽  
2004 ◽  
Vol 54 (2) ◽  
pp. 500-504 ◽  
Author(s):  
Patrick Beauchesne ◽  
Jean-François Mosnier ◽  
Thierry Schmitt ◽  
Jacques Brunon
Keyword(s):  
Stereotactic Biopsy ◽  
Clinical Presentation ◽  
Positive Response ◽  
Cerebral Peduncle ◽  
Nerve Sheath Tumor ◽  
Chemotherapy Treatment ◽  
Nerve Sheath Tumors ◽  
Nerve Sheath ◽  
The Right ◽  
First Time

Abstract OBJECTIVE AND IMPORTANCE Schwannomas occurring in the neuraxis are very rare. Usually, these tumors are benign. Primary malignant intracerebral nerve sheath tumors are extremely rare, with only five documented cases in the international literature. We report one case of a primary malignant intracerebral nerve sheath tumor occurring in the right cerebral peduncle of a 35-year-old man. CLINICAL PRESENTATION Magnetic resonance imaging revealed a heterogeneous peripherally enhancing mass of the right cerebral peduncle, surrounded by a small edema. INTERVENTION Unlike the five cases previously reported, this is the first time a stereotactic biopsy has been performed, and this is the only patient who responded to cranial radiation therapy for approximately 2 years. When the tumor recurred, a systemic chemotherapy treatment was prescribed. No positive response was seen, and the patient died 29 months after the initial diagnosis. CONCLUSION An accurate diagnosis and planned aggressive treatment seem to be the key elements in the management of the disease.

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