Scintiscan Characteristics of Normal Thyroid Gland in a Region of Known Iodine Intake

1976 ◽  
Vol 15 (02) ◽  
pp. 60-62
Author(s):  
Lucille E. Snoop ◽  
G. T. Krishnamurthy

SummaryMorphological features of a normal thyroid gland in a geographical region where the daily iodine intake is about 1 mg are established. The mean weight of the thyroid gland is 31.3 gm with a range from 19 to 43 gm. Oblique length of the right lobe is 5.0 cm and that of the left lobe 4.8 cm. The surface area of the right and left lobes is 9.7 and 9.1 cm2, respectively. The weight of the thyroid gland calculated on the basis of the scan obtained with 99mTcO4 is quite variable and shows poor correlation (γ = 0.40) with the weight obtained on the basis of I-131 scan. It is suggested that the criteria of normalcy be established regionally based on iodine intake, and that an isotope of iodine be used in calculating the weight of thyroid gland for dosimetry purposes.

1991 ◽  
Vol 124 (3) ◽  
pp. 238-244 ◽  
Author(s):  
Raija M. Takalo ◽  
Hanna P. Mäkäräinen ◽  
R. Kaarina Jaakkola

Abstract. The purpose of this work was to determine by ultrasound the volume and echo structure of the thyroid gland in 13-year-old schoolchildren in northern Finland. 76 healthy schoolchildren underwent cervical ultrasound examinations during the period of Jan-Feb 1990, performed with a real-time scanner using a 7.5 MHz linear transducer and direct contact method. The volume of each lobe was calculated according to the formula for a volume of rotation ellipsoid by multiplication of maximal thickness, width and height of the lobe by the correction factor 0.479. Any focal lesion that could be distinguished in the homogenous thyroid parenchyma was assessed for echogenicity as compared with the normal thyroid gland and was measured with electronic calipers. The mean thyroid volume was 6.5±1.6 ml (mean ±sd), being 6.3±1.8 ml in the boys and 6.7± 1.4 ml in the girls. The sex difference was not significant. The right lobe was significantly larger than the left one (mean 3.7 and 2.8 ml, respectively). Thyroid volume was correlated with body weight and body surface area in both sexes. Abnormal lesions in terms of echo structure were noted in one subject (1.3%). Comparing the results with the findings reported from other countries, it can be concluded that the thyroid volume in these 13-year-old Finnish schoolchildren was about 30% less than that reported for the same age group in the FRG (with insufficient iodine intake) and about 35% more than in 13-year-old schoolchildren in Sweden (with sufficient iodine intake).


Author(s):  
A. J. Salaam ◽  
S. M. Danjem ◽  
A. A. Salaam ◽  
H. A. Angba ◽  
P. O. Ibinaiye

Objective: To sonographically determine the thyroid gland volume in normal adults in Jos University Teaching Hospital, as well as how it relates to anthropometric factors. Background: The thyroid gland is one of the largest endocrine glands in the body weighing about 10-25g.  It regulates the rate of metabolism and controls the growth and rate of function of many other systems in the body. These it does, by producing thyroid hormones, principally thyroxine (T4) and triiodothyronine (T3). The accurate estimation of the size of the thyroid is very important for the evaluation and management of thyroid disorders. Thus, knowing the normal size in a geographic location would form a baseline for detecting abnormalities. Ultrasonography is a cheap, readily available, easy to perform and non-invasive method to image the thyroid gland, hence its use in this resource-limited setting. Methods: This is a cross-sectional study of sonographic measurement of thyroid gland volume on 400 normal (healthy) adults in Jos, Plateau State, Northern part of Nigeria. All examinations were performed using LOGIC 5, a real-time ultrasound machine using a 10MHZ linear transducer and ultrasound transmission gel to act as a coupling gel. Measurements of each lobe and isthmus were obtained in longitudinal (length), transverse (width) and depth(breath) in centimetres (cm). Blood samples were taken for thyroid function tests. The weight and heights were obtained. The data obtained were statistically analyzed using SPSS software version 17. The results were presented in forms of tables, graphs and chart. Results: The mean thyroid volume for males   6.03 cm3±2.22 was higher than that of females 5.62 cm3±2.14. The mean right lobe volume (RLV) was 3.09 cm3±1.47 and that of males and females were 3.16 cm3 ±1.34 and 3.04 cm3 ±1.55 respectively. The mean left lobe volume (LLV) was 2.69 cm3 ± 1.37 and that of males and females were 2.89 cm3±1.32 and 2.57 cm3±1.39 respectively. The right lobe volume was significantly greater than the left lobe(p=0.000). The total mean isthmus volume was 0.27 cm3±0.31. The mean isthmus volume in males 0.3±0.28 is significantly higher than that of females 0.24±0.23 (p=0.025). The BMI increases in females with increasing age. BMI and BSA are higher in males. Conclusion: The volume obtained in this study was slightly lower than those reported by previous studies in Nigerian adults. The right lobe volume was higher than that of the left and the volume was higher in males compared to females. Anthropometric parameters were noted to affect the thyroid volume.


2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Ümit Yaşar Ayaz ◽  
Sevin Ayaz ◽  
Mehmet Ercüment Döğen ◽  
Arman Api

Thyroid hemiagenesis is a rare congenital anomaly in which one lobe of thyroid gland fails to develop. It is much rarer in males. There is a higher incidence of associated thyroid disorders in patients with thyroid hemiagenesis; therefore early and prompt diagnosis is important for children. We present the ultrasonographic and scintigraphic findings of thyroid hemiagenesis in an eight-year-old-boy. On ultrasonography (US), left lobe of the thyroid gland could not be demonstrated and the right lobe showed minimal hyperplasia. Its echogenicity was normal and no nodule was seen. On thyroid scintigraphy, left lobe of thyroid gland or any ectopic thyroid tissue could not be demonstrated, while the right lobe showed minimal hyperplasia. Without performing any invasive procedure, we enrolled the child in a follow-up program with the guidance of US and scintigraphy, which were effective both in making the final diagnosis of thyroid hemiagenesis and in evaluating the current status of the present thyroid tissue. In conclusion, if only one thyroid lobe is detected in a pediatric case initially with US or scintigraphy, the diagnosis of thyroid hemiagenesis should be suggested and, before any unnecessary or invasive attempt, the other complementary method (scintigraphy/US) should be performed.


1925 ◽  
Vol 42 (2) ◽  
pp. 193-200 ◽  
Author(s):  
J. Hamilton Crawford ◽  
J. N. J. Hartley

1. In a series of rabbits the changes which took place in the histology of the left lobe of the thyroid gland after excision of the right lobe have been studied at varied intervals of time. 2 days after the removal of one lobe the other lobe showed a slightly increased colloid content, an increased vacuolation of the colloid, and a slight increase in the size of the epithelial cells. At the end of a week the vesicles were greatly increased in size, distended with colloid, and the epithelial cells were flattened, while after 3 to 4 months signs of compensatory hypertrophy were present. 2. The changes observed were uninfluenced by division of the vagus or cervical sympathetic.


2013 ◽  
Vol 57 (8) ◽  
pp. 659-662 ◽  
Author(s):  
Zhe Zhang ◽  
Chengjiang Li

Thyroidal 99mTc uptake in the acute thyrotoxic phase of subacute thyroiditis (SAT) is always inhibited. However, a patient with SAT had signs in the right-side thyroid gland with transient thyrotoxicosis and slightly high 99mTc uptake levels in the right lobe, low 99mTc uptake in the left lobe, and normal overall uptake. Histological examination showed cellular destruction and granulomatous inflammatory changes in the right lobe, with marked interstitial fibrosis in the left lobe. The patient was thyrotrophin-receptor antibody (TRAb) positive. After a short course of prednisolone, SAT-like symptoms and signs improved. TRAb-positivity resolved spontaneously after 22 months, and TSH levels were slightly low for 22 months. Levels then kept normal in the following four years. In conclusion, high 99mTc uptake by the right lobe was due to the combined effects of TRAb and left thyroid gland fibrosis.


2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P41-P41
Author(s):  
Eugene P. Snissarenko ◽  
Grace H Kim ◽  
Alfred A Simental ◽  
Jon E. Zwart ◽  
Darron M. Ransbarger ◽  
...  

Objective The minimally invasive video-assisted thyroidectomy (MIVAT) technique was first pioneered in Europe in the 1990s. It has shown to have comparable results to traditional thyroidectomy and additional advantages such as better cosmetic results as well as faster recovery. This project aims to analyze the results from the MIVAT procedure utilizing a 2-person technique over the initial 2 years of inception at an academic training center. Methods Retrospective review of 170 cases between May 2006 and September 2007 at LLUMC. The demographic and clinical data collected includes age, sex, incision, operative times, hospitalization, identification of recurrent laryngeal nerves, pathology, size of the dominant nodule and entire gland, and postoperative complications. Results 23 male and 147 female patients underwent MIVAT by a single surgeon; of those, 59 total thyroidectomies and 111 hemithyroidectomies were performed. The mean incision length was 3.5cm. The average weight/volume on pathology was 19.25g/19cm3, 21.03g/22cm3 and 31.29g/40cm3 for the right lobe, left lobe, and entire gland respectively. Average nodule size was 3.6cm3. The mean surgical time was 91.7 minutes and the mean blood loss was 31cc. Average hospitalization stay was 1.43 days. 17 patients experienced temporary hypocalcemia, and 1 patient remained hypocalcemic for more then 6 months. Two patients experienced transient pitch problems, 7 patients experienced temporary unilateral vocal cord paresis, and 1 patient experienced mild diplophonia. Conclusions While enabling smaller surgical access for thyroidectomy, 2-surgeon technique MIVAT can be performed safely and quickly. Voice problems were the most common complications that usually resolved in 8 weeks.


2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 14574-14574
Author(s):  
G. Demir ◽  
R. U. Gürsu ◽  
S. Pekmezci ◽  
K. Kaynak

14574 Forty eight patients (24 males and 24 females) with colorectal carcinoma and lung or hepatic metastasis who had undergone metastasectomy were evaluated retrospectively. The mean age was 58.12±8.34 years (43–79 years). The mean age of the males was 60.16±8.21 years (47–79 years), while it was 56.08±8.13 years in the females (43–71 years). Among the 48 metastasectomies that were performed, 11 were pulmonary metastases, and 37 were hepatic metastases. The mean time to the hepatic metastasectomy after primary surgery was 324.37±420.04. Among the hepatic metastases, one was located in the caudate lobe, 16 were located in the right lobe, and 20 were located in the left lobe. Thirty of the patients had received postoperative chemotherapy after liver metastasectomy. Twenty two of the patients who underwent liver metastasectomy (59%) had a recurrence. In 14 of these, (38%) the recurrence was in the liver. Overall survival of the patients with liver metastasectomy was 914.19±577.08 days. Survival after metastasectomy was 578.80±331.54 days. On the other hand, the mean time to pulmonary metastasectomy after primary surgery was 811.81±552.06 days. Eight of the lung metastases were located in the right lobe, whereas 3 were located in the left lobe. Three patients had concomittant metastases in the right upper and lower lobes, and one patient had additional liver metastasis. Eight of the patients who underwent pulmonary metastasectomy had received postoperative chemotherapy. Five of the patients who underwent pulmonary metastasectomy (45%) had a recurrence. Two of the patients had recurrence in the lung, while 3 had recurrence elsewhere. Overall survival of the patients who underwent pulmonary metastasectomy after initial surgery was 1341.54±816.21 days. Survival after metastasectomy was 528.81±365.45 days while recurrence-free survival after pulmonary metastasctomy was 342.18±125.71 days. Conclusion: This study suggests that patients with pulmonary metastasectomies have even beter clinical outcomes then hepatic metastasectomies in patients with metastatic coloercatla cencer. Every effort should be made to perform both pulmonary and hepatic metastasectomies in this group of patients. No significant financial relationships to disclose.


Author(s):  
Amit Poonia ◽  
Anuradha Gupta ◽  
Varinder Uppal

Background: The thyroid gland is vital endocrine gland which secretes three hormones i.e. thyroxin (T4), triiodothyronine (T3) and Calcitonin hormones. The thyroxin (T4) and triiodothyronine (T3) hormones are biologically active and are required for maintenance of normal levels of metabolic activity. The thyroid also produces calcitonin from the parafollicular cells which act directly on osteoclast to decrease the bone resorption which lower the blood calcium level. Deficient or excessive production of thyroid hormones may lead to serious pathological states with outward symptoms. Methods: The gross anatomical and biometrical studies were conducted on thyroid gland of buffalo, sheep and goat (n=12) collected immediately after slaughtering from slaughter house and local meat shop. The weight of thyroid gland was measured by weighing balance, volume by water displacement method, length and width of lateral lobes and isthmus by calibrated scale and inelastic thread and thickness of lateral lobes and isthmus was measured by digital vernier calliper. The data was analysed statistically. Result: The lateral lobes were roughly triangular in buffalo and elongated in sheep and oval in goat. The surfaces were granular and rough in buffalo but smooth in sheep and goat. It extended from thyroid cartilage to 2nd tracheal ring in buffalo, 1st to 6th tracheal ring in sheep and 1st to 7th tracheal ring in goat. The left lobe was larger than the right lobe in all the three species studied. The thyroid gland was biggest in buffalo followed by goat and smallest in sheep. The density of isthmus was more than the lobes in sheep and goat but not in buffalo.


2020 ◽  
Vol 10 (2) ◽  
pp. 1776-1778
Author(s):  
Pallavi Srivastava ◽  
Nidhi Anand ◽  
Nuzhat Husain

Primary Synovial sarcoma of the thyroid gland is a rare sarcoma. We report a case of synovial sarcoma of the thyroid gland in a 2-yr-old boy presenting with a palpable progressively increasing neck mass, high resolution ultrasound revealed a heterogeneous lesion measuring 5 x 4 cm identified in the right lobe compressing the left lobe. A total thyroidectomy was performed and grossly both the lobes were involved. Histologically, the tumor was a biphasic synovial sarcoma which was confirmed by immunohistochemical markers showing positive expression for vimentin, Epithelial membrane antigen &Transducin-like enhancer of split-1. This is an unusual location for the occurrence of primary synovial sarcoma and aggressive nature the early diagnosis is difficult, and no definite treatment regimens are being defined due to the rarity of neoplasm.


2017 ◽  
Vol 2017 ◽  
pp. 1-5
Author(s):  
Hiroki Sato ◽  
Kiyoaki Tsukahara ◽  
Ray Motohashi ◽  
Midori Wakiya ◽  
Hiromi Serizawa ◽  
...  

Background. Thyroid carcinoma complicated by hemiagenesis is very rare, and previous reports have not described this cancer on the side of the absent lobe. Methods and Results. We report the case of a 64-year-old woman in whom left thyroid hemiagenesis was discovered incidentally during investigations of abnormal sensation during swallowing. A tumorous 1.4 cm lesion was also found on the side of the absent lobe, left of the isthmus. Fine-needle aspiration biopsy revealed class V papillary carcinoma, but no lymph node metastases. Total thyroidectomy was performed for stage cT1bN0M0 carcinoma. Histopathology revealed normal thyroid tissues in the right lobe and isthmus, while the left lobe was absent. The mostly papillary carcinoma was adjacent to the truncated thyroid tissue, with a portion histologically consistent with poorly differentiated carcinoma. Conclusions. All previously reported cases of thyroid cancer complicated by hemiagenesis have represented carcinoma occurring within the present lobe. This case is extremely rare.


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