scholarly journals Mitral Valve Repair in Infants with Ventricular Septal Defect Combined with Mitral Regurgitation

2018 ◽  
Vol 66 (S 01) ◽  
pp. S1-S110
Author(s):  
Y. Kulyabin ◽  
Y. Gorbatykh ◽  
I. Soynov ◽  
A. Zubritskiy ◽  
A. Bogachev-Prokophiev
2017 ◽  
Vol 26 (1) ◽  
pp. 106-111 ◽  
Author(s):  
Yuriy Y Kulyabin ◽  
Ilya A Soynov ◽  
Alexey V Zubritskiy ◽  
Alexey V Voitov ◽  
Nataliya R Nichay ◽  
...  

1996 ◽  
Vol 62 (6) ◽  
pp. 1773-1777 ◽  
Author(s):  
Kouichi Hisatomi ◽  
Tadashi Isomura ◽  
Tohru Sato ◽  
Kenichi Kosuga ◽  
Kiroku Ohishi ◽  
...  

2018 ◽  
Vol 11 (2) ◽  
pp. 85-92
Author(s):  
Yuriy Yu Kulyabin ◽  
Ilya A Soynov ◽  
Alexey V Zubritskiy ◽  
Alexey V Voitov ◽  
Nataliya R Nichay ◽  
...  

OBJECTIVES: This study aimed to assess mitral valve function after repair of ventricular septal defect (VSD) combined with mitral regurgitation (MR) in the mid-term follow-up period, to evaluate the clinical utility of simultaneous mitral valve repair (MVR). METHODS: From June 2005 to March 2014, 60 patients with VSD and MR underwent surgical treatment. After performing propensity score analysis (1:1) for the entire sample, 46 patients were selected and divided into 2 groups: those with VSD closure and MVR - 23 patients and those with VSD closure without mitral valve intervention - 23 patients. The follow-up period - 32 (28;40) months. RESULTS: There was no postoperative mortality in either group. There was no significant difference in the duration of the postoperative period between groups. Mean cardiopulmonary bypass time and aortic cross-clamping time were significantly longer in the 'VSD + MVR' group (cardiopulmonary bypass, P=0.023; aortic cross-clamp, P< 0.001). There was no significant difference in regurgitation area (P=0.30) and MR grade (P= 0.76) between groups postoperatively. There was no significant difference in freedom from MR ≥ 2+ between groups (log-rank test, P= 0.28). The only significant risk factor for recurrent MR ≥ 2+ during the follow-up period was mild residual MR in the early postoperative period ( P=0.037). CONCLUSIONS: In infants with VSD combined with MR, simultaneous MVR has no benefits simultaneous MVR provided no advantage over that of isolated VSD closure. We found that the presence of mild residual MR in the early postoperative period predisposes the development of MR ≥ 2+ in follow-up period.


Author(s):  
Fabian Barbieri ◽  
Ulf Landmesser ◽  
Mario Kasner ◽  
Markus Reinthaler

Abstract Background Chronic mitral regurgitation is one of the most common valvular heart diseases and is associated with poor outcome. Although other structural diseases are regularly seen in such patients, concomitant atrial septal defects remain a rarity in the elderly. Case summary We report a case of an 82-year old woman with progressive right-sided heart failure due to mitral regurgitation and an atrial septal defect of secundum type, despite optimal medical therapy. Combined transcatheter mitral valve repair by utilizing a separate transseptal puncture and atrial septal defect closure was performed resulting in amelioration of symptoms. Discussion Procedural planning for simultaneous transcatheter therapies of coupled structural heart disease entities remains complex. Our case illustrates feasibility of percutaneous edge-to-edge mitral valve repair and consecutive closure of a large secundum atrial septal defect. Different options of accessing the left atrium should be discussed on an individual basis, while additional atrial septal defect closure may be beneficial in terms of right ventricular function and symptoms of right heart failure.


2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
T Benito Gonzalez ◽  
X Freixa ◽  
C Godino ◽  
M Taramasso ◽  
R Estevez-Loureiro ◽  
...  

Abstract Background Limited information has been reported regarding the impact of percutaneous mitral valve repair (PMVR) on ventricular arrhythmic (VA) burden. The aim of this study was to address the incidence of VA and appropriate antitachycardia implantable cardiac defibrillator (ICD) therapies before and after PMVR. Methods We retrospectively analyzed all consecutive patients with heart failure with reduce left ventricular ejection fraction, functional mitral regurgitation grade 3+ or 4+ and an active ICD or cardiac resynchronizer who underwent PMVR in any of the eleven recruiting centers. Only patients with complete available device VA monitoring from one-year before to one year after PMVR were included. Baseline clinical and echocardiographic characteristics were collected before PMVR and at 12-months follow-up. Results 93 patients (68.2±10.9 years old, male 88.2%) were enrolled. PMVR was successfully performed in all patients and device success at discharge was 91.4%. At 12-months follow-up, we observed a significant reduction in mitral regurgitation severity, NT-proBNP and prevalence of severe pulmonary hypertension and severe kidney disease. Patients also referred a significant improvement in NYHA functional class and showed a non-significant trend to reserve left ventricular remodeling. After PMVR a significant decrease in the incidence of non-sustained ventricular tachycardia (VT) (5.0–17.8 vs 2.7–13.5, p=0.002), sustained VT or ventricular fibrillation (0.9–2.5 vs 0.5–2.9, p=0.012) and ICD antitachycardia therapies (2.5–12.0 vs 0.9–5.0, p=0.033) were observed. Conclusion PMVR was related to a reduction in arrhythmic burden and ICD therapies in our cohort. Proportion of patients who presented ven Funding Acknowledgement Type of funding source: None


Sign in / Sign up

Export Citation Format

Share Document