Accelerated Clustered Sparse Acquisition to Improve Functional MRI for Mapping Language Functions

2019 ◽  
Vol 81 (02) ◽  
pp. 095-104
Author(s):  
Phillip Keil ◽  
Charlotte Nettekoven ◽  
Kilian Weiss ◽  
Thorsten Lichtenstein ◽  
Roland Goldbrunner ◽  
...  
Keyword(s):  
Picture Naming ◽  
Acoustic Noise ◽  
Inferior Frontal Gyrus ◽  
Statistical Parametric Mapping ◽  
Silent Period ◽  
Naming Task ◽  
Sparse Sampling ◽  
Acquisition Protocol ◽  
Local Activation ◽  
Language Functions

Abstract Background Functional magnetic resonance imaging (fMRI) is a useful method for noninvasive presurgical functional mapping. However, the scanner environment is inherently unsuitable for the examination of auditory and language functions, due to the loud acoustic noise produced by the scanner. Interleaved acquisition methods alleviate this problem by providing a silent period for stimulus presentation and/or response control (sparse sampling) but at the expense of a diminished amount of data collected. There are possible improvements to these sparse acquisition methods that increase the amount of data by acquiring several images per event (clustered sampling). We tested accelerated clustered fMRI acquisition in comparison with conventional sparse sampling in a pilot study. Methods The clustered and sparse acquisition techniques (7.4 minutes scanning time per protocol) were directly compared in 15 healthy subjects (8 men; mean age: 24 ± 3 years) using both a motor (tongue movement) and a language (overt picture-naming) task. Functional imaging data were analyzed using Statistical Parametric Mapping software (SPM12 Wellcome Department of Imaging Neuroscience, London, UK). For both tasks, activation levels were compared and Euclidean distances (EDs) between cluster centers (i.e., local activation maxima and centers of gravity) were calculated. Overlaps and laterality indices were computed for the picture-naming task. In addition, the feasibility of the clustered acquisition protocol in a clinical setting was assessed in one pilot patient. Results For both tasks, activation levels were higher using the clustered acquisition protocol, reflected by bigger cluster sizes (p < 0.05). Mean ED between cluster centers ranged between 9.9 ± 5.4 mm (left superior temporal gyrus; centers of gravity) and 16.6 ± 13.2 mm (left inferior frontal gyrus; local activation maxima) for the picture-naming task. Overlaps between sparse and clustered acquisition reached 88% (Simpson overlap coefficient). A similar activation pattern for both acquisition methods was also confirmed in the clinical case. Conclusion Despite some drawbacks inherent to the acquisition technique, the clustered sparse sampling protocol showed increased sensitivity for activation in language-related cortical regions with short scanning times. Such scanning techniques may be particularly advantageous for investigating patients with contraindications for long scans (e.g., reduced attention span).

Simulation of Aphasic Naming Performance in Non-Brain-Damaged Adults

2004 ◽  
Vol 47 (3) ◽  
pp. 610-623 ◽  
Author(s):  
JoAnn P. Silkes ◽  
Malcolm R. McNeil ◽  
Mathias Drton
Keyword(s):  
Picture Naming ◽  
Low Frequency ◽  
Naming Task ◽  
Control Group ◽  
Coding System ◽  
Language Performance ◽  
Cognitive Demands ◽  
Error Type ◽  
Performance Deficits ◽  
Language Functions

Discussion abounds in the literature as to whether aphasia is a deficit of linguistic competence or linguistic performance and, if it is a performance deficit, what are its precise mechanisms. Considerable evidence suggests that alteration of nonlinguistic factors can affect language performance in aphasia, a finding that raises questions about the modularity of language and the purity of linguistic mechanisms underlying the putative language deficits in persons with aphasia. This study investigated whether temporal stress plus additional cognitive demands placed on non-brain-damaged adults would produce aphasic-like performance on a picture naming task. Two groups of non-brain-damaged participants completed a picture naming task with additional cognitive demands (use of low frequency words and making semantic judgments about the stimuli). A control group performed this task at their own pace, and an experimental group was placed under time constraints. Naming errors were identified and coded by error type. Errors made by individuals with aphasia from a previous study (S. E. Kohn & H. Goodglass, 1985) were recoded with the coding system used in the present study and were then compared with the types of errors produced by the 2 non-brain-damaged groups. Results generally support the hypothesis that the language performance deficits seen in persons with aphasia exist on a continuum with the language performance of non-brain-damaged individuals. Some error type differences between groups warrant further investigation. KEY WORDS : aphasia, language functions and disorders, anomia, verbal expression

Neural correlates of naming errors across different neurodegenerative diseases

Neurology ◽  
2020 ◽  
Vol 95 (20) ◽  
pp. e2816-e2830 ◽  
Author(s):  
Eleonora Catricalà ◽  
Cristina Polito ◽  
Luca Presotto ◽  
Valentina Esposito ◽  
Arianna Sala ◽  
...  
Keyword(s):  
Picture Naming ◽  
Group Analysis ◽  
Statistical Parametric Mapping ◽  
Occipital Lobe ◽  
Naming Task ◽  
Neural Correlates ◽  
Fusiform Gyrus ◽  
Single Subject ◽  
Middle Temporal ◽  
Semantic Errors

ObjectiveTo investigate the types of errors produced in a picture naming task by patients with neurodegenerative dementia due to different etiologies and their neural correlates.MethodsThe same standardized picture naming test was administered to a consecutive sample of patients (n = 148) who had been studied with [18F] FDG-PET. The errors were analyzed in 3 categories (visual, semantic, and phonologic). The PET data were analyzed using an optimized single-subject procedure, and the statistical parametric mapping multiple regression design was used to explore the correlation between each type of error and brain hypometabolism in the whole group. Metabolic connectivity analyses were run at the group level on 7 left hemisphere cortical areas corresponding to an a priori defined naming network.ResultsSemantic errors were predominant in most patients, independent of clinical diagnosis. In the whole group analysis, visual errors correlated with hypometabolism in the right inferior occipital lobe and in the left middle occipital lobe. Semantic errors correlated with hypometabolism in the left fusiform gyrus, the inferior and middle temporal gyri, and the temporal pole. Phonologic errors were associated with hypometabolism in the left superior and middle temporal gyri. Both positive (occipital–posterior fusiform) and negative (anterior fusiform gyrus and the superior anterior temporal lobe) connectivity changes were associated with semantic errors.ConclusionsNaming errors reflect the dysfunction of separate stages of the naming process and are specific markers for different patterns of brain involvement. These correlations are not limited to primary progressive aphasia but extend to other neurodegenerative dementias.

Coining Compounds and Derivations - A Crosslinguistic Elicitation Study of Word-Formation Abilities of Preschool Children and Adults in Polish and English

2009 ◽  
Vol 40 (4) ◽  
pp. 176-192 ◽  
Author(s):  
Ewa Haman ◽  
Andrea Zevenbergen ◽  
Melissa Andrus ◽  
Marta Chmielewska
Keyword(s):  
Preschool Children ◽  
Picture Naming ◽  
Native Language ◽  
General Pattern ◽  
Naming Task ◽  
Word Formation ◽  
Elicitation Study ◽  
American Children ◽  
To Come

Coining Compounds and Derivations - A Crosslinguistic Elicitation Study of Word-Formation Abilities of Preschool Children and Adults in Polish and English This paper examines word-formation abilities in coining compounds and derivatives in preschool children and adult speakers of two languages (English and Polish) differing in overall word-formation productivity and in favoring of particular word-formation patterns (compounding vs. derivation). An elicitation picture naming task was designed to assess these abilities across a range of word-formation categories. Adult speakers demonstrated well-developed word-formation skills in patterns both typical and non-typical for their native language. In contrast with adult results, preschool children predominantly coined innovations conforming to the general pattern of their language: Polish children favoring derivation and American children favoring compounding. The results show that although children are improving their wordformation skills during the preschool years, they need much more experience to come to the mature proficiency in using the variety of word-formation patterns available in their language.

Gestural symbolic strategies in children with Down syndrome

Gesture ◽  
2020 ◽  
Vol 19 (2-3) ◽  
pp. 299-334
Author(s):  
Arianna Bello ◽  
Silvia Stefanini ◽  
Pasquale Rinaldi ◽  
Daniela Onofrio ◽  
Virginia Volterra
Keyword(s):  
Down Syndrome ◽  
Picture Naming ◽  
Item Analysis ◽  
Naming Task ◽  
Typically Developing ◽  
Typically Developing Children ◽  
Children With Down Syndrome ◽  
Communicative Development ◽  
Developmental Age ◽  
Representational Gestures

Abstract In early communicative development, children with Down syndrome (DS) make extensive use of gestures to compensate for articulatory difficulties. Here, we analyzed the symbolic strategies that underlie this gesture production, compared to that used by typically developing children. Using the same picture-naming task, 79 representational gestures produced by 10 children with DS and 42 representational gestures produced by 10 typically developing children of comparable developmental age (3;1 vs. 2;9, respectively) were collected. The gestures were analyzed and classified according to four symbolic strategies. The two groups performed all of the strategies, with no significant differences for either choice or frequency of the strategies used. The item analysis highlighted that some photographs tended to elicit the use of the same strategy in both groups. These results indicate that similar symbolic strategies are active in children with DS as in typically developing children, which suggests interesting similarities in their symbolic development.

The Development of Fundamental Frequency in 6- to 10-Year Old Children: A Brief Study

1998 ◽  
Vol 28 (1-2) ◽  
pp. 55-62 ◽  
Author(s):  
S. P. Whiteside ◽  
C. Hodgson
Keyword(s):  
Standard Deviation ◽  
Fundamental Frequency ◽  
Picture Naming ◽  
Age Groups ◽  
Naming Task ◽  
Final Position ◽  
The Mean ◽  
Age And Sex

This brief study investigates the development of fundamental frequency (FO) in pre-adolescent children as a function of age and sex. The children who took part in the study were divided into three age groups: 6, 8 and 10 years. Each group consisted of three males and three females. Each subject produced nine target phrases with [] in phrase-final position, which were elicited via a picture-naming task. FO was estimated for the nine target utterances and the following FO parameters were derived: mean FO for the whole phrase; FO range for the whole phrase; standard deviation values of FO for the whole phrase and mean FO for the phrase-final vowel [α:]. Results indicated that FO parameters generally decreased with age, and by age 10 years the males had lower values than the females for all four parameters. Results also indicated that the mean standard deviation of FO across the phrase was significantly higher for the females compared to that for the males.

Plurals as modifiers in Dutch and English noun-noun compounds express plurality in production

2013 ◽  
Vol 8 (1) ◽  
pp. 53-74 ◽  
Author(s):  
Arina Banga ◽  
Esther Hanssen ◽  
Anneke Neijt ◽  
Robert Schreuder
Keyword(s):  
Picture Naming ◽  
Naming Task ◽  
Native English Speakers ◽  
English Speakers ◽  
Semantic Constraints ◽  
Noun Compounds ◽  
English Noun

The present study investigates the relation between conceptual plurality and the occurrence of a plural morpheme in novel Dutch and English noun-noun compounds. Using a picture-naming task, we compared the naming responses of native Dutch speakers and native English speakers to pictures depicting either one or multiple instances of the same object serving as a possible modifier in a novel noun-noun compound. While the speakers of both languages most frequently produced novel compounds containing a singular modifier, they also used compounds containing a plural modifier and did this more often to describe a picture with several instances of an object than to describe a picture with one instance of the object. Speakers of English incorporated some regular plurals into the noun-noun compounds they produced. These results contradict the words-and-rules theory of Pinker (1999) and also the semantic constraints for compounding put forth by Alegre and Gordon (1996). Interestingly, it appears, however, that the acceptability constraints put forth by Haskell, MacDonald, and Seidenberg (2003) apply to the production of compounds.

scholarly journals The Cologne Picture Naming Test for Language Mapping and Monitoring (CoNaT): An Open Set of 100 Black and White Object Drawings

2021 ◽  
Vol 12 ◽  
Author(s):  
Carolin Weiss Lucas ◽  
Julia Pieczewski ◽  
Sophia Kochs ◽  
Charlotte Nettekoven ◽  
Christian Grefkes ◽  
...  
Keyword(s):  
Task Performance ◽  
Brain Tumour ◽  
Educational Level ◽  
Picture Naming ◽  
Healthy Subjects ◽  
Clinical Use ◽  
Language Mapping ◽  
Black And White ◽  
Language Functions ◽  
Open Set

Language assessment using a picture naming task crucially relies on the interpretation of the given verbal response by the rater. To avoid misinterpretations, a language-specific and linguistically controlled set of unambiguous, clearly identifiable and common object–word pairs is mandatory. We, here, set out to provide an open-source set of black and white object drawings, particularly suited for language mapping and monitoring, e.g., during awake brain tumour surgery or transcranial magnetic stimulation, in German language. A refined set of 100 black and white drawings was tested in two consecutive runs of randomised picture order and was analysed in respect of correct, prompt, and reliable object recognition and naming in a series of 132 healthy subjects between 18 and 84 years (median 25 years, 64% females) and a clinical pilot cohort of 10 brain tumour patients (median age 47 years, 80% males). The influence of important word- and subject-related factors on task performance and reliability was investigated. Overall, across both healthy subjects and patients, excellent correct object naming rates (97 vs. 96%) as well as high reliability coefficients (Goodman–Kruskal's gamma = 0.95 vs. 0.86) were found. However, the analysis of variance revealed a significant, overall negative effect of low word frequency (p &lt; 0.05) and high age (p &lt; 0.0001) on task performance whereas the effect of a low educational level was only evident for the subgroup of 72 or more years of age (p &lt; 0.05). Moreover, a small learning effect was observed across the two runs of the test (p &lt; 0.001). In summary, this study provides an overall robust and reliable picture naming tool, optimised for the clinical use to map and monitor language functions in patients. However, individual familiarisation before the clinical use remains advisable, especially for subjects that are comparatively prone to spontaneous picture naming errors such as older subjects of low educational level and patients with clinically apparent word finding difficulties.

scholarly journals Comparing the cognate effect in spoken and written second language word production

2019 ◽  
Author(s):  
Merel Muylle ◽  
Eva Van Assche ◽  
Robert Hartsuiker
Keyword(s):  
Second Language ◽  
Picture Naming ◽  
Language Production ◽  
Naming Task ◽  
Written Language ◽  
Word Production ◽  
Error Pattern ◽  
Underlying Processes

Cognates – words that share form and meaning between languages – are processed faster than control words. However, it is unclear whether this effect is merely lexical (i.e., central) in nature, or whether it cascades to phonological/orthographic (i.e., peripheral) processes. This study compared the cognate effect in spoken and typewritten production, which share central, but not peripheral processes. We inquired whether this effect is present in typewriting, and if so, whether its magnitude is similar to spoken production. Dutch-English bilinguals performed either a spoken or written picture naming task in English; picture names were either Dutch-English cognates or control words. Cognates were named faster than controls and there was no cognate-by-modality interaction. Additionally, there was a similar error pattern in both modalities. These results suggest that common underlying processes are responsible for the cognate effect in spoken and written language production, and thus a central locus of the cognate effect.

scholarly journals Does Object Size Matter with Regard to the Mental Simulation of Object Orientation?

2018 ◽  
Author(s):  
Sau-Chin Chen ◽  
Bjorn de Koning ◽  
Rolf Antonius Zwaan
Keyword(s):  
Picture Naming ◽  
Naming Task ◽  
Mental Simulation ◽  
Object Orientation ◽  
Orientation Effect ◽  
Object Size ◽  
Verification Task ◽  
Potential Explanation ◽  
Size Matter ◽  
Theoretical Considerations

Language comprehenders have been argued to mentally represent the implied orientation of objects. However, compared to the effects of shape, size, and color, the effect of orientation is rather small. We examined a potential explanation for the relatively low magnitude of the orientation effect: object size moderates the orientation effect. Theoretical considerations led us to predict a smaller orientation effect for small objects than for large objects in a sentence-picture verification task. We furthermore investigated whether this pattern generalizes across languages (Chinese, Dutch, and English) and tasks (picture-naming task). The results of the verification task show an orientation effect overall, which is not moderated by object size (contrary to our hypothesis) and language (consistent with our hypothesis). Meanwhile the preregistered picture-picture verification task showed the predicted interaction between object size and orientation effect. We conducted exploratory analyses to address additional questions.

scholarly journals Naming pictures and sounds: Stimulus type affects semantic context effects

2020 ◽  
Author(s):  
Stefan Wöhner ◽  
Andreas Mädebach ◽  
Jörg D. Jescheniak
Keyword(s):  
Picture Naming ◽  
Context Effect ◽  
Context Effects ◽  
Semantic Category ◽  
Naming Task ◽  
Semantic Context ◽  
Perceptual Processing ◽  
Semantic Interference ◽  
Lexical Processes ◽  
Naming Tasks

Semantic context effects obtained in naming tasks have been most influential in devising and evaluating models of word production. We re-investigated this effect in the frequently used blocked-cyclic naming task in which stimuli are presented repeatedly either sorted by semantic category (homogeneous context) or intermixed (heterogeneous context). Previous blocked-cyclic naming studies have shown slower picture naming responses in the homogeneous context. Our study compared this context effect in two task versions, picture naming and sound naming. Target words were identical across task versions (e.g., participants responded with the word “dog” to either the picture of that animal or to the sound [barking] produced by it). We found semantic interference in the homogeneous context also with sounds and the effect was substantially larger than with pictures (Experiments 1 and 2). This difference is unlikely to result from extended perceptual processing of sounds as compared to pictures (Experiments 3 and 4) or from stronger links between pictures and object names than between sounds and object names (Experiment 5). Overall, our results show that semantic context effects in blocked-cyclic naming generalize to stimulus types other than pictures and – in part – also reflect pre-lexical processes that depend on the nature of the stimuli used for eliciting the naming responses.

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