scholarly journals PROSTHODONTIC REHABILITATION OF A PATIENT WITH ORAL SUBMUCOUS FIBROSIS AND MICROSTOMIA : A CASE REPORT

2012 ◽  
Vol 02 (02) ◽  
pp. 68-71
Author(s):  
Anupama Prasad D. ◽  
Krishna Prasad D. ◽  
Chethan Hegde
Keyword(s):  
Case Report ◽  
Female Patient ◽  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Complete Denture ◽  
Limited Mouth Opening ◽  
Submucous Fibrosis

AbstractThis case report deals with treatment of a female patient aged 45 years with limited mouth opening due to submucous fibrosis ,who was completely edentulous and was prosthetically treated with modification of techniques for impression making and jaw relation so that a complete denture was made without sections which could be easily inserted and removed without compromising retention and esthetics.

scholarly journals Immunohistochemical Analysis of Myofibroblasts Using α- SMA in Oral Submucous Fibrosis Turning into Malignancy- A Case Report and Review

2021 ◽  
pp. 192-198
Author(s):  
Swapan Kumar Purkait ◽  
. Abhinandan ◽  
Nimisha Priya ◽  
Sriyanshi Singh ◽  
Sneha Singh
Keyword(s):  
Case Report ◽  
Immunohistochemical Study ◽  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Immunohistochemical Analysis ◽  
Invasive Front ◽  
Premalignant Condition ◽  
Submucous Fibrosis ◽  
Very High ◽  
Premalignant Conditions

Oral submucous fibrosis is a premalignant condition, characterized by fibrosis in oral mucosa causing stiffness of mucosa and leading to reduced mouth opening. The malignant transformation of oral submucous fibrosis is very high among the rest of the premalignant conditions. Chronic chewing of arecanut causes production of myofibroblasts. These myofibroblasts plays an important role in neoangiogenesis as well as disintegration of the basement membrane at the tumor invasive front leading to carcinoma.  Here, we are doing an Immunohistochemical study using alpha SMA for proper microscopic visulizations of myofibroblastic activity in an OSF patient, encompassing the pathogenesis and malignant potentiality of the disease.

scholarly journals Prosthodontic Management of a Completely Edentulous Patient with Microstomia and Flat Ridge Mandible: A Case Report

2019 ◽  
Vol 53 (6) ◽  
Author(s):  
Michael Josef Kridanto Kamadjaja ◽  
Fatty Nada Pertiwi
Keyword(s):  
Case Report ◽  
Mouth Opening ◽  
Complete Denture ◽  
Edentulous Patient ◽  
Limited Mouth Opening ◽  
Proper Diagnosis

It is difficult to make impression and fabricate conventional dentures for patients with microstomia and flat ridge. This is a case report of 53-year-old female with limited mouth opening (25 mm) who had been wearing denture for 7 years and which was recently broken. Close mouth with suction impression method was used. Proper diagnosis and appropriate set of procedures and methods were needed for this patient. The conventional complete denture fitted with closed mouth method for this condition resulted in retentive and stable denture which was inserted and removed easily.

scholarly journals Distribution of Oral Submucous Fibrosis Cases and Malignant Transformation Rate among Bhutanese Patients Treated at Jigme Dorji Wangchuck National Referral Hospital, Bhutan

2021 ◽  
Vol 4 (12) ◽  
pp. OR7-OR10
Author(s):  
Pratap Singh Tamang ◽  
Gyan Prasad Bajgai ◽  
Hari Prasad Pokhrel
Keyword(s):  
Retrospective Study ◽  
Malignant Transformation ◽  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Referral Hospital ◽  
Transformation Rate ◽  
Limited Mouth Opening ◽  
High Burden ◽  
Submucous Fibrosis ◽  
National Referral Hospital

BACKGROUND: Oral Submucous Fibrosis (OSMF) is a chronic, insidious, scarring disease of the mouth often involving the palate, oro-pharynx, pharynx, esophagus, tongue and the buccal mucosa which leads to ulceration, blanching and ultimately limited mouth opening. The aim of the study is to describe the age, gender and district-wise distribution of oral submucous fibrosis cases and to assess the malignant transformation rate among the patients with oral submucous fibrosis who were treated at Jigme Dorji Wangchuck National Referral Hospital, Thimphu, Bhutan.MATERIALS AND METHOD: This is a descriptive retrospective study. The patients were clinically diagnosed by examining their mouth and by measuring their mouth opening (Inter-incisal height). Patients who had less than 3 fingers mouth opening and diagnosed as Oral submucous fibrosis (OSMF) during these three-year period from 2018 to 2020 were considered for the study.RESULTS: There were 278 cases in total. Thimphu district had the maximum number of cases followed by Wangduephodrang and Samtse. Gasa and Haa districts had the minimum cases. More males were affected than females. The malignant transformation rate among these patients was 4.3%.CONCLUSION: Thimphu district had the highest proportion of OSMF cases and was almost equally distributed among genders. Over 90% of the patients reported improvement without surgery while the malignancy transformation rate was 4.3%. The study recommends conducting screening in districts with high burden of OSMF cases for early diagnosis and treatment.

scholarly journals Quality of Life in Oral Submucous Fibrosis- A Case Report with a Literature Review

2021 ◽  
Vol 15 (1) ◽  
pp. 4-10
Author(s):  
Shishir Ram Shetty ◽  
Sesha Reddy ◽  
Pooja Narain Adtani ◽  
Raghavendra Shetty ◽  
Ashwin Lakshminarayanan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Case Report ◽  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Specific Questionnaire ◽  
Spicy Food ◽  
Potentially Malignant ◽  
Submucous Fibrosis ◽  
Published Research

Introduction: Oral Submucous Fibrosis (OSMF) is a potentially malignant disorder commonly found in the Southeast Asian region, classically characterized through restricted mouth opening and burning sensation in the mouth on consuming spicy food. The etiopathogenesis and treatment aspects of OSMF have been extensively researched and reviewed. However, the effect of this condition on the Quality of Life (QoL) of patients has not gained much consideration. The aim of our case report is to highlight the importance of evaluating the QoL in an OSMF patient by using discipline-specific questionnaire and also to present to the readers a review of the recently published research articles on the application of QoL questionnaires in OSMF patients. Results: It was observed that most of the researchers used generic and discipline-specific questionnaire for evaluating the quality of life in OSMF patients. Conclusion: Evaluation of QoL is recommended during the treatment of OSMF patients. There is a need to develop and employ more of disease-specific QoL instruments for OSMF patients.

scholarly journals PROSTHETIC MANAGEMENT OF ORAL SUBMUCOUS FIBROSIS: A CASE REPORT AN INNOVATIVE METHOD FOR FABRICATION OF SECTIONAL DENTURES

2017 ◽  
Vol 7 ◽  
Author(s):  
Sheela Kumari ◽  
Rathika Rai
Keyword(s):  
Case Report ◽  
Oral Submucous Fibrosis ◽  
Complete Denture ◽  
Prosthetic Rehabilitation ◽  
Innovative Method ◽  
Oral Opening ◽  
Submucous Fibrosis

Prosthetic rehabilitation of microstomia patients due to oral submucous fibrosis presents difficulties at all stages as the maximal oral opening is smaller than the size of a complete denture. Several techniques have been described for use when either standard impression trays or the denture itself becomes too difficult to place and remove from the mouth. This article describes a different design for the fabrication of maxillary and mandibular sectional trays to enable easier and efficient impression making in a patient with limited oral opening.

scholarly journals Rebamipide to Manage Stomatopyrosis in Oral Submucous Fibrosis

2016 ◽  
Vol 17 (12) ◽  
pp. 1009-1012 ◽  
Author(s):  
Joanna Baptist ◽  
Shrijana Shakya
Keyword(s):  
Repeated Measures ◽  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Standard Of Care ◽  
Burning Sensation ◽  
Limited Mouth Opening ◽  
Repeated Measures Analysis ◽  
Intralesional Steroid ◽  
Submucous Fibrosis ◽  
Oral Burning

ABSTRACT Introduction Oral submucous fibrosis (OSF) causes progressive debilitating symptoms, such as oral burning sensation (stomatopyrosis) and limited mouth opening. The standard of care (SOC) protocol includes habit cessation, intralesional steroid and hyaluronidase injections, and mouth opening exercises. The objective of the study was to evaluate efficacy of rebamipide in alleviating burning sensation of the oral mucosa in OSF in comparison with SOC intralesional steroid injections. Materials and methods Twenty OSF patients were divided into two groups [rebamipide (100 mg TID for 21 days) and betamethasone (4 mg/mL biweekly for 4 weeks)] of 10 each by random sampling. Burning sensation was assessed every week for 1 month. Burning sensation scores were analyzed using repeated measures analysis of variance (ANOVA) and paired t-test. Results Change in burning sensation score was significant (p < 0.05) in the first four visits. However, score between the 4th and 5th visit was not statistically significant (p > 0.05). Conclusion Our study has shown that rebamipide can be considered as an effective modality to manage burning sensation in patients suffering from OSF. Clinical significance Considering stomatopyrosis and trismus as a major cause for inability to eat in OSF, use of newer adjunctive modalities, such as rebamipide will ease patients suffering and also encourage them to consume food. How to cite this article Baptist J, Shakya S, Ongole R. Rebamipide to Manage Stomatopyrosis in Oral Submucous Fibrosis. J Contemp Dent Pract 2016;17(12):1009-1012.

scholarly journals Comparative Study of Intralesional Dexamethasone Plus Hyaluronidase & Oral Colchicine in Patients with Oral Submucous Fibrosis

2018 ◽  
Vol 14 (2) ◽  
pp. 60-65
Author(s):  
Ganesh Prasad Neupane ◽  
Maya Rai ◽  
R. S. Rathore ◽  
V. K. Bhargava ◽  
A. K. Mahat ◽  
...  
Keyword(s):  
Treatment Outcomes ◽  
Oral Mucosa ◽  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Study Groups ◽  
T Test ◽  
Significant Difference ◽  
Intralesional Injections ◽  
Submucous Fibrosis ◽  
Larger Sample

Introduction: Oral Submucous Fibrosis (OSMF) is a precancerous condition of the oral mucosa. It is characterized by excessive production of collagen leading to inelasticity of the oral mucosa and atrophic changes of the epithelium.Aim and objective: To evaluate the efficacy of oral Colchicine in comparison to intralesional injections of Dexamethasone plus Hyaluronidase in the management of OSMF patients.Materials and Methods: Fourty patients with OSMF were randomly divided equally into two groups. 20 patients in Dexamethasone group received biweekly intralesional injections of Dexamethasone (4mg/ml) plus Hyaluronidase 1500 IU in buccal mucosa for a period of 12 weeks. Other 20 patients in Colchicine group received oral Colchicine 0.5 mg tablets twice daily for 12 weeks. Parameters taken in the study were burning sensation, and mouth opening. Descriptive statistics, paired t test and unpaired t test were used for statistical analysis.Results and Conclusions: The pre- and post-treatment differences were found to be statistically significant for both the groups (p<0.001) and for both the treatment outcomes. When the average difference of the treatment outcomes was compared between the two study groups, statistically highly significant difference was noted (p <0.001) only in mouth opening but not in burning sensation.These encouraging results should prompt further clinical trials with Colchicine on a larger sample size to broaden the therapeutic usefulness of the drug in the management of OSMF. JNGMC,  Vol. 14 No. 2 December 2016, Page: 60-65

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