Ligaclip for Preauricular Skin Tags in the Newborn

2020 ◽  
Author(s):  
Fabrizio Shonauer ◽  
Antonio Guastafierro ◽  
Elisabetta Grasso ◽  
Sara Izzo ◽  
Giovanni Francesco Nicoletti ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Retrospective Study ◽  
Hair Follicle ◽  
Clinical Examination ◽  
Benign Lesions ◽  
Pilosebaceous Unit ◽  
Skin Tag ◽  
Careful Clinical Examination ◽  
Skin Tags

Abstract Introduction Skin tags are benign lesions, that often represent only an aesthetic problem; if subjected to trauma, they can occasionally bleed with possible infection and pain. When they occur in the preauricular region, attention should be paid to the diagnosis and approach; in fact, controversy exists in the differential diagnosis between hair follicle nevi, accessory tragus, and skin tag. Misdiagnosis and failure of treatment can lead to serious consequences, such as chondritis. Materials and Methods In our retrospective study, we evaluated 19 newborns affected by single, unilateral skin tag in the preauricular region. Each patient underwent a careful clinical examination; lesions without a pilosebaceous unit and with a thin, soft pedicle were treated in the nursery with Ligaclip (Johnson & Johnson). Results Skin tag falls between day 7 and 10. We had no cases of edema, cellulitis, clip loss, or bleeding. Scarring results were extremely satisfactory at 3-month follow-up. Conclusion We believe that after a careful clinical examination, cases of skin tags in the preauricular area can be selected and treated with Ligaclip. This procedure can be considered rapid, safe, economical, and simple in the newborn patients.

scholarly journals Fracture of the posterior malleolus: an underdiagnosed condition

2017 ◽  
Vol 3 (2) ◽  
pp. 310
Author(s):  
Luís D. Silva ◽  
Bruno Maia ◽  
Eduardo Cruz Ferreira ◽  
Filipa Pires ◽  
Luís Camarinha
Keyword(s):  
Differential Diagnosis ◽  
Clinical Examination ◽  
Ankle Sprain ◽  
Conventional Radiography ◽  
Ankle Sprains ◽  
Sports Activity ◽  
Posterior Malleolus ◽  
Isolated Fracture ◽  
Low Incidence

<p class="abstract">The ankle joint is the most commonly injured joint during sports activity. While ankle sprains occur more frequently, ankle fractures are less common. Due to its low incidence, the isolated fracture of the posterior malleolus still represents a diagnosis challenge. This article reports a case of a female with a posterior malleolus isolated fracture after falling while performing sports activity. Clinical examination and conventional radiography were consistent with diagnosis of a simple ankle sprain and the patient was discharged with a conservative approach for lateral ankle sprain. Due to persistent pain the patient return for additional examination, which the differential diagnosis revealed an isolated fracture of the posterior malleolus without displacement of the fragment. The patient was immobilized with a suropodalic splint for 4 weeks followed by additional conservative. At the fourth month of follow-up, the patient was asymptomatic and showed good clinical and functional outcomes. This case highlights the importance of a comprehensive medical history and detailed clinical examination which may reveal pathological features that require a differential diagnosis<span lang="EN-IN">.</span></p>

scholarly journals Osteomyelitis of the mandible with pseudotumoral manifestation

2016 ◽  
Vol 11 (2) ◽  
pp. 200-203
Author(s):  
A. ZAMFIR-CHIRU-ANTON ◽  
◽  
A.E. STANCIU ◽  
D.C. GHEORGHE ◽  
◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Clinical Examination ◽  
Correct Diagnosis ◽  
Cellular Infiltration ◽  
Osteolytic Lesions ◽  
Case Presentation ◽  
Infectious Origin ◽  
Uncommon Disease ◽  
Diagnosis Therapy

Osteomyelitis of the mandible is an uncommon disease, sometimes with severe invalidating symptoms. Some cases can present as tumors of the jaw and are possibly seen in ENT practice. Objective. To present the differential diagnosis of mandibular swellings of inflammatory origin. Material, method. Case presentation of a 9y child admitted and biopsied in the ENT department. Results. Histologic examination showed focal areas of osteolytic lesions along with moderate inflammatory cellular infiltration, all within newly formed bone. Under NSAI drugs, the symptoms were alleviated, the patient remaining under close follow-up. Conclusion. Osteomyelitis of the mandible is not always of infectious origin. The clinical examination, the imagistics and biopsy are key elements to correct diagnosis. Therapy is still under evaluation for noninfectious osteomyelitis.

Tumor Diagnosis

1982 ◽  
Vol 40 ◽  
pp. 262-265
Author(s):  
Bruce Mackay
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Differential Diagnosis ◽  
Light Microscopy ◽  
Clinical Examination ◽  
Ultrastructural Study ◽  
Diagnostic Procedures ◽  
Specific Diagnosis ◽  
Transmission Electron ◽  
Microscopic Diagnosis

The broadest application of transmission electron microscopy (EM) in diagnostic medicine is the identification of tumors that cannot be classified by routine light microscopy. EM is useful in the evaluation of approximately 10% of human neoplasms, but the extent of its contribution varies considerably. It may provide a specific diagnosis that can not be reached by other means, but in contrast, the information obtained from ultrastructural study of some 10% of tumors does not significantly add to that available from light microscopy. Most cases fall somewhere between these two extremes: EM may correct a light microscopic diagnosis, or serve to narrow a differential diagnosis by excluding some of the possibilities considered by light microscopy. It is particularly important to correlate the EM findings with data from light microscopy, clinical examination, and other diagnostic procedures.

Nano-Lipidic Carriers as a Tool for Drug Targeting to the Pilosebaceous Units

2020 ◽  
Vol 26 (27) ◽  
pp. 3251-3268
Author(s):  
Shweta Ramkar ◽  
Abhishek K. Sah ◽  
Nagendra Bhuwane ◽  
Ishwari Choudhary ◽  
Narayan Hemnani ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Hair Follicle ◽  
Hair Follicles ◽  
Prolonged Release ◽  
Pilosebaceous Unit ◽  
Tissue Targeting ◽  
Bulge Region ◽  
Drug Reservoir ◽  
Fast Transport ◽  
Topical Applications

The pilosebaceous unit is the triad comprising of hair follicle, arrector pilli muscle, and sebaceous gland. Drug delivery to and through the hair follicles has garnered much attention of the researchers and the hair follicles represent an attractive target site via topical applications. They are bordered by capillaries and antigenpresenting cells, connected to the sebaceous glands and the bulge region of the hair follicle anchors the stem cells. The nano lipid carriers have the propensity to penetrate through the skin via transcellular route, intracellular route and follicular route. It has been established that nano lipid carriers have the potential for follicular drug delivery and provide some advantages over conventional pathways, including improved bioavailability, enhanced penetration depth, fast transport into the skin, tissue targeting and form a drug reservoir for prolonged release. This review describes the pilosebaceous unit (PSU) and related diseases and the recent lipid-based nanotechnology approaches for drug delivery to the follicular unit as well as related issues. Different types of nano lipid carriers, including ethosomes, liposomes, nanoparticles, solid lipid nanoparticles (SLNs), and nano lipid carriers (NLCs) have been reported for follicular drug delivery. Targeted drug delivery with nano-lipid carriers has the potential to augment the efficacy of drugs/bioactives to treat diseases of PSU. This review systematically introduces the activities of different formulations and the use of nano lipid carriers in treating PSU related disorders like alopecia, acne, and hirsutism.

Clinical Value of Computer-Assisted Taylor Three-dimensional External Fixation in the Treatment of Tibiofibular Fracture (Preprint)

2020 ◽  
Author(s):  
Hongfeng Sheng ◽  
Weixing Xu ◽  
Bin Xu ◽  
Hongpu Song ◽  
Di Lu ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Internal Fixation ◽  
External Fixation ◽  
External Fixator ◽  
Theoretical Basis ◽  
New Technology ◽  
Three Dimensional ◽  
Computer Assisted ◽  
Clinical Value

UNSTRUCTURED The retrospective study of Taylor's three-dimensional external fixator for the treatment of tibiofibular fractures provides a theoretical basis for the application of this technology. The paper collected 28 patients with tibiofibular fractures from the Department of Orthopaedics in our hospital from March 2015 to June 2018. After the treatment, the follow-up evaluation of Taylor's three-dimensional external fixator for the treatment of tibiofibular fractures and concurrency the incidence of the disease, as well as the efficacy and occurrence of the internal fixation of the treatment of tibial fractures in our hospital. The results showed that Taylor's three-dimensional external fixator was superior to orthopaedics in the treatment of tibiofibular fractures in terms of efficacy and complications. To this end, the thesis research can be concluded as follows: Taylor three-dimensional external fixation in the treatment of tibiofibular fractures is more effective, and the incidence of occurrence is low, is a new technology for the treatment of tibiofibular fractures, it is worthy of clinical promotion.

Hand eczema patients’ knowledge of skin protection following a guided talk—A retrospective study with a follow‐up questionnaire

2019 ◽  
Vol 81 (2) ◽  
pp. 117-123 ◽  
Author(s):  
Yasemin Topal ◽  
Tove Agner ◽  
Janique van der Heiden ◽  
Niels E. Ebbehøj ◽  
Kim K. B. Clemmensen
Keyword(s):  
Retrospective Study ◽  
Hand Eczema ◽  
Skin Protection

Skeletal and Dental Correction and Stability Following LeFort I Advancement in Patients With Cleft Lip and Palate With Mild, Moderate, and Severe Maxillary Hypoplasia

2021 ◽  
pp. 105566562199610
Author(s):  
Buddhathida Wangsrimongkol ◽  
Roberto L. Flores ◽  
David A. Staffenberg ◽  
Eduardo D. Rodriguez ◽  
Pradip. R. Shetye
Keyword(s):  
Retrospective Study ◽  
Outcome Measures ◽  
Cleft Lip ◽  
Outcome Measure ◽  
Cleft Lip And Palate ◽  
Inclusion Criteria ◽  
Maxillary Hypoplasia ◽  
Main Outcome Measure ◽  
Lateral Cephalograms

Objective: This study evaluates skeletal and dental outcomes of LeFort I advancement surgery in patients with cleft lip and palate (CLP) with varying degrees of maxillary skeletal hypoplasia. Design: Retrospective study. Method: Lateral cephalograms were digitized at preoperative (T1), immediately postoperative (T2), and 1-year follow-up (T3) and compared to untreated unaffected controls. Based on the severity of cleft maxillary hypoplasia, the sample was divided into 3 groups using Wits analysis: mild: ≤0 to ≥−5 mm; moderate: <−5 to >−10 mm; and severe: ≤−10 mm. Participants: Fifty-one patients with nonsyndromic CLP with hypoplastic maxilla who met inclusion criteria. Intervention: LeFort I advancement. Main Outcome Measure: Skeletal and dental stability post-LeFort I surgery at a 1-year follow-up. Results: At T2, LeFort I surgery produced an average correction of maxillary hypoplasia by 6.4 ± 0.6, 8.1 ± 0.4, and 10.7 ± 0.8 mm in the mild, moderate, and severe groups, respectively. There was a mean relapse of 1 to 1.5 mm observed in all groups. At T3, no statistically significant differences were observed between the surgical groups and controls at angle Sella, Nasion, A point (SNA), A point, Nasion, B point (ANB), and overjet outcome measures. Conclusions: LeFort I advancement produces a stable correction in mild, moderate, and severe skeletal maxillary hypoplasia. Overcorrection is recommended in all patients with CLP to compensate for the expected postsurgical skeletal relapse.

Sign in / Sign up

Export Citation Format

Share Document