scholarly journals A Case Report of Bulky Venous Malformation in the Parapharyngeal Space

2020 ◽  
Vol 03 (01) ◽  
pp. e10-e15
Author(s):  
Yuki Sato ◽  
Takao Hamamoto ◽  
Takashi Ishino ◽  
Tsutomu Ueda ◽  
Masay Takumida ◽  
...  

AbstractVenous malformations commonly occur in the head and neck regions, in the mucous membrane of the nasal and oral cavities. Venous malformations are found in the extremities in 40% of cases, in the trunk in 20% of cases, and in the cervicofacial area in 40% of cases. However, they are rarely encountered in the parapharyngeal space. We report our experience of surgical treatment of a patient with this rare tumor. The patient was a 21-year-old man who presented with a left mandibular swelling and was admitted to a nearby hospital. He was referred to our hospital for examination and treatment. Contrast-enhanced computed tomography (CT) revealed a bulky tumor with some calcification in the parapharyngeal space; on contrast-enhanced CT, the tumor showed some enhanced effects in the arterial and venous phases. Additional enhancement magnetic resonance imaging (MRI) showed the lesion as low signal intensity on T1-weighted images and as high signal intensity on T2-weighted images, and contrast-enhanced MRI showed some enhanced effects of the lesion. Based on these findings, we suspected venous malformation and performed surgical excision. Histopathology confirmed the venous malformation, and the lesion was diagnosed as a cavernous angioma. Vascular malformations in the head and neck regions should be precisely diagnosed so that appropriate multimodality treatment can be undertaken.

2007 ◽  
Vol 17 (1) ◽  
pp. 280-284 ◽  
Author(s):  
Y. Konishi ◽  
H. Sato ◽  
T. Fujimoto ◽  
H. Tanaka ◽  
O. Takahashi ◽  
...  

Primary uterine angiosarcoma is exceedingly rare and has a poor prognosis. Moreover, the radiologic findings of this disease have not been previously documented. We present a case of a 62-year-old woman with primary uterine angiosarcoma who underwent abdominal hysterectomy and bilateral salpingo-oophorectomy. Histologically, interlacing vascular spaces were lined by endothelial cells showing nuclear pleomorphism and mitotic activity. Immunohistochemical staining was positive for the endothelial cell markers CD31, CD34, and Factor VIII, supporting the diagnosis of primary uterine angiosarcoma. Magnetic resonance imaging (MRI) revealed a heterogeneous mass with high and low signal intensity (T2 weighted) in the uterus and an intense contrast-enhanced anterior area within the mass (gadolinium enhanced, T1 weighted). The lesion was also enhanced on computed tomography (CT). Radiologically, the most helpful sign in the characterization of uterine angiosarcoma is marked heterogeneity on T2-weighted MRI with focal areas of high signal intensity, known as the “cauliflower-like appearance.” In addition, findings of a strongly enhanced lesion on gadolinium-enhanced T1-weighted MRI and contrast-enhanced CT also support the diagnosis of angiosarcoma


2016 ◽  
Vol 32 (9) ◽  
pp. 628-633 ◽  
Author(s):  
Ahmed Abdel Khalek Abdel Razek ◽  
Germeen Ashmalla Albair ◽  
Sieza Samir

Aim To classify venous malformations based on contrast-enhanced MR angiography that may serve as a basis for treatment plan. Patients and methods A retrospective analysis was performed in 58 patients with venous malformations who underwent contrast-enhanced MR angiography. Venous malformations were classified according to their venous drainage into: type I, isolated malformation without peripheral drainage; type II, malformation that drains into normal veins; type III, malformation that drains into dilated veins; and type IV, malformation that represents dysplastic venous ectasia. Image analysis was done by two reviewers. Intra and inter-observer agreement of both reviewers and intra-class correlation was done. Results The intra-observer agreement of contrast-enhanced MR angiography classification of venous malformations was excellent for the first reviewer ( k = 0.83, 95% CI = 0.724–0.951, P = 0.001) and substantial for the second reviewer ( K = 0.79, 95% CI = 0.656-0.931, P = 0.001). The inter-observer agreement of contrast-enhanced MR angiography classification of venous malformations was excellent for both reviewers at the first time ( K = 0.96, 95% CI = 0.933–1.000, P = 0.001) and second time ( k = 0.81, 95% CI = 0.678–0.942, P = 0.001). There was high intra-class correlation of both reviewers for single measure ( ICC = 0.85, 95% CI = 0.776–0.918, P = 0.001) and for average measures ( ICC = 0.96, 95% CI = 0.933–0.978, P = 0.001). Conclusion Contrast-enhanced MR angiography classification of venous malformations may be a useful, simple and reliable tool to accurately classify venous malformation and this topographic classification helps for better management strategy.


2018 ◽  
Vol 129 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Yu Fujii ◽  
Yoshihiro Muragaki ◽  
Takashi Maruyama ◽  
Masayuki Nitta ◽  
Taiichi Saito ◽  
...  

OBJECTIVEWHO Grade III gliomas are relatively rare and treated with multiple modalities such as surgery, chemotherapy, and radiotherapy. The impact of the extent of resection (EOR) on improving survival in patients with this tumor type is unclear. Moreover, because of the heterogeneous radiological appearance of Grade III gliomas, the MRI sequence that best correlates with tumor volume is unknown. In the present retrospective study, the authors evaluated the prognostic significance of EOR.METHODSClinical and radiological data from 122 patients with newly diagnosed WHO Grade III gliomas who had undergone intraoperative MRI–guided resection at a single institution between March 2000 and December 2011 were analyzed retrospectively. Patients were divided into 2 groups by histological subtype: 81 patients had anaplastic astrocytoma (AA) or anaplastic oligoastrocytoma (AOA), and 41 patients had anaplastic oligodendroglioma (AO). EOR was calculated using pre- and postoperative T2-weighted and contrast-enhanced T1-weighted MR images. Univariate and multivariate analyses were performed to evaluate the prognostic significance of EOR on overall survival (OS).RESULTSThe 5-, 8-, and 10-year OS rates for all patients were 74.28%, 70.59%, and 65.88%, respectively. The 5- and 8-year OS rates for patients with AA and AOA were 72.2% and 67.2%, respectively, and the 10-year OS rate was 62.0%. On the other hand, the 5- and 8-year OS rates for patients with AO were 79.0% and 79.0%; the 10-year OS rate is not yet available. The median pre- and postoperative T2-weighted high–signal intensity volumes were 56.1 cm3 (range 1.3–268 cm3) and 5.9 cm3 (range 0–180 cm3), respectively. The median EOR of T2-weighted high–signal intensity lesions (T2-EOR) and contrast-enhanced T1-weighted lesions were 88.8% (range 0.3%–100%) and 100% (range 34.0%–100%), respectively. A significant survival advantage was associated with resection of 53% or more of the preoperative T2-weighted high–signal intensity volume in patients with AA and AOA, but not in patients with AO. Univariate analysis showed that preoperative Karnofsky Performance Scale score (p = 0.0019), isocitrate dehydrogenase 1 (IDH1) mutation (p = 0.0008), and T2-EOR (p = 0.0208) were significant prognostic factors for survival in patients with AA and AOA. Multivariate analysis demonstrated that T2-EOR (HR 3.28; 95% CI 1.22–8.81; p = 0.0192) and IDH1 mutation (HR 3.90; 95% CI 1.53–10.75; p = 0.0044) were predictive of survival in patients with AA and AOA.CONCLUSIONST2-EOR was one of the most important prognostic factors for patients with AA and AOA. A significant survival advantage was associated with resection of 53% or more of the preoperative T2-weighted high–signal intensity volume in patients with AA and AOA.


1988 ◽  
Vol 69 (4) ◽  
pp. 535-539 ◽  
Author(s):  
Daniele Rigamonti ◽  
Robert F. Spetzler ◽  
Burton P. Drayer ◽  
W. Michel Bojanowski ◽  
John Hodak ◽  
...  

✓ The magnetic resonance (MR) imaging appearance of venous malformations, all angiographically verified, was evaluated in 11 patients. A venous malformation is characteristically depicted as a tubular area of decreased signal intensity in the white matter of the brain. In one patient, a histologically verified cavernous malformation was also present with a characteristic mixed signal-intensity core on the T2-weighted MR images. Care should be used when evaluating venous angiomas to exclude the presence of a lesion with associated prominent venous drainage, such as a glioma.


2021 ◽  
Vol 2 (1) ◽  
pp. 22-35
Author(s):  
Dmitry Yu. Komelyagin ◽  
Svetlana V. Yamatina ◽  
Alexey V. Petukhov ◽  
Zhanna R. Omarova ◽  
Kira A. Blagikh ◽  
...  

Introduction. Children with various forms of vascular malformations of the tongue are an extremely complex patient population for a number of reasons: the quality of life of the child is significantly reduced – in addition to cosmetic problems, occur functional disorders, characterized by impaired breathing, act of swallowing, chewing food, speech, the appearance of pain syndrome, the child’s social adaptation worsens; the uniqueness of each clinical case, which requires an individual approach to the treatment of a particular child; frequent combination of malformation (malformation of all types of vessels – arterial, venous, lymphatic); the absence of a clear algorithm for the diagnosis and treatment of this group of patients in the domestic and foreign literature. In this regard, the full rehabilitation of such children requires a search for optimal treatment methods, the purpose of which is to achieve a stable good functional and cosmetic result. Materials and methods. 37 children aged 1 to 17 years with lymphatic, lymphovenous, lymphoarteriovenous and venous malformations of the tongue were treated. The average age of the children was 4.7 years. In addition to general clinical data, the mandatory examination methods were – ultrasonography of pathological tissues of the head and neck, study of the blood coagulation system (thromboelastography, thrombodynamics, coagulogram), Doppler ultrasonography of the head and neck vessels, transcranial Doppler, fibrolaryngoscopy, MRI (magnetic resonance imaging) and CT (computed tomography) of the head and neck with intravenous contrast agent. All children underwent surgical treatment; 6 – puncture-sclerosing method with 3 % solution of aethoxysklerol (with venous malformation of the tongue); 9 – curly resection of the tongue and its subsequent plastic surgery with local tissues (with macroglossia in children with lymphatic, lymphovenous and lymphoarteriovenous malformations of the tongue); 31 – laser treatment (with a superficial form of lymphatic, lymphovenous and lymphoarteriovenous malformations of the tongue). It is worth noting that 9 children out of 31 who underwent laser treatment, the first stage was performed curly resection of the tongue and its subsequent plastic surgery with local tissues. Thus, 46 operations were performed on 37 children. To carry out laser treatment was used a laser apparatus LSP-»IRE-Polyus» (ЛСП-«ИРЭ-Полюс»), which allows working with two wavelengths (0.97 μm and 1.55 μm) in two modes (pulse and pulse-periodic). All operations were performed under general anaesthesia. Results. A diagnostic algorithm has been created, new methods for treating children with various forms of vascular malformations of the tongue have been developed and introduced into practice. A good result was achieved in 37 children (100 %). There were no complications. A patent for invention No. 2676832 was obtained for the method of laser treatment. The maximum observation period is 3.5 years. Conclusions. When managing patients with vascular malformations of the tongue, it is necessary to adhere to a clear diagnostic algorithm. Treatment of patients should take place in a multidisciplinary hospital and be interdisciplinary in nature. Treatment should be started immediately when complaints appear; expectant tactics are not warranted. After the treatment and the achievement of a good clinical result, dynamic monitoring of the patient is necessary.


2021 ◽  
Vol 3 (3) ◽  
pp. e200131
Author(s):  
Derek Hsu ◽  
Tanya J. Rath ◽  
Barton F. Branstetter ◽  
Yoshimi Anzai ◽  
C. Douglas Phillips ◽  
...  

OTO Open ◽  
2018 ◽  
Vol 2 (3) ◽  
pp. 2473974X1879706 ◽  
Author(s):  
Ebrahim Karimi ◽  
Mehrdad Jafari ◽  
Keyvan Aghazadeh ◽  
Saeed Sohrabpour ◽  
Fatemeh Tavakolnejad

Objective The purpose of this study was to discuss the clinical outcomes and complications of treating venous malformations with sclerotherapy, with sodium tetradecyl sulfate as the sclerosing agent. Study Design Case series with planned data collection. Setting Amiralam Hospital—a referral otolaryngology–head and neck surgery hospital affiliated with Tehran University of Medical Sciences. Subjects and Methods A total of 345 patients with venous malformations were treated with sclerotherapy with sodium tetradecyl sulfate 3% (1 mL for every 1 cm3 of the lesion). The venous malformation location, treatments before the current sclerotherapy with sodium tetradecyl sulfate, the number of sclerotherapy sessions, and complications resulting from sclerotherapy were recorded. Follow-up assessments were done for a minimum of 1 year following the procedure. A favorable outcome was defined as a 50% decrease in the lesion size based on clinical and radiologic assessments. Results A total of 759 injection sessions were documented, ranging from 1 to 6 injections per patient (mean = 3.1). The follow-up duration ranged from 12 to 84 months (mean = 55 months). Based on clinical assessment, a 50% reduction of size was reported for 95.6% of the patients. According to the imaging before and after the procedures, a 50% reduction of size was seen among 67.3% of the patients. Conclusion The results of the study showed that the use of sodium tetradecyl sulfate as a sclerosing substance can effectively reduce the size of venous malformation lesions.


2021 ◽  
pp. 80-82
Author(s):  
B.V Subhash ◽  
Alba Dinesh ◽  
Seema Patil ◽  
Asha R Iyengar ◽  
Revan Kumar Joshi ◽  
...  

The vascular anomalies consist of vascular tumours and vascular malformations. One among these are the venous malformations which constitute about 40% of all vascular malformations. Usually, the venous malformations present as localized lesions in the form of swellings/nodules with phleboliths, are diagnosed by ultrasonography, CT and MRI. Summary: This is a report of a rare longstanding case of wide spread venous malformations of oral cavity and facial area with phleboliths.


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