EFFECTS OF BENIGN AUDITORY STIMULSTION ON CEREBRAL OXIDATIVE METABOLISM AND CEREBRAL BLOOD FLOW IN PRETERM INFANTS

2006 ◽  
Vol 37 (S 1) ◽  
Author(s):  
H Lai
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Preterm Infants ◽  
Oxidative Metabolism ◽  
Cerebral Oxidative Metabolism

Effect of CO2 and 100% O2 on cerebral blood flow in preterm infants

1980 ◽  
Vol 48 (3) ◽  
pp. 468-472 ◽  
Author(s):  
F. A. Leahy ◽  
D. Cates ◽  
M. MacCallum ◽  
H. Rigatto
Keyword(s):  
Carbon Dioxide ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Preterm Infants ◽  
Cerebral Circulation ◽  
Pressure Change ◽  
Venous Occlusion ◽  
Co2 Sensitivity ◽  
Important Regulator ◽  
Carbon Dioxide Pressure

To determine 1) the effect of arterial CO2 change on the neonatal cerebral circulation and 2) whether 100% O2 would produce significant decrease in cerebral blood flow (CBF), we studied 24 preterm infants to explain the late (5 min) hyperventilation observed in them during hyperoxia. Of these, 12 were studied before and during inhalation of 2-3% CO2 and 12 before and during the inhalation of 100% O2. We measured CBF by a modification of the venous occlusion plethysmography technique and found that CBF increased 7.8% per Torr alveolar carbon dioxide pressure change and that it decreased 15% with 100% O2. These findings suggest that 1) CO2 is an important regulator of CBF in the perterm infant, 2) CBF-CO2 sensitivity in these infants may be greater than in adult subjects, 3) 100% O2 reduced CBF significantly, and 4) a decrease in CBF during administration of 100% O2 may be at least partially responsible for the increase in ventilation with hyperoxia.

Influence of Sleep State and Respiratory Pattern on Cyclical Fluctuations of Cerebral Blood Flow Velocity in Healthy Preterm Infants

Neonatology ◽  
1996 ◽  
Vol 69 (6) ◽  
pp. 357-367 ◽  
Author(s):  
Virender K. Rehan ◽  
Carlos A. Fajardo ◽  
Zia Haider ◽  
Ruben E. Alvaro ◽  
Donald B. Gates ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Flow Velocity ◽  
Preterm Infants ◽  
Blood Flow Velocity ◽  
Cerebral Blood Flow Velocity ◽  
Respiratory Pattern ◽  
Sleep State ◽  
Cyclical Fluctuations

Cerebral Blood Flow Velocity Regulation in Preterm Infants

Neonatology ◽  
1991 ◽  
Vol 59 (6) ◽  
pp. 329-335 ◽  
Author(s):  
Margot van de Bor ◽  
Frans J. Walther
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Flow Velocity ◽  
Preterm Infants ◽  
Blood Flow Velocity ◽  
Cerebral Blood Flow Velocity

scholarly journals Acute effect of glucose on cerebral blood flow, blood oxygenation, and oxidative metabolism

2014 ◽  
Vol 36 (2) ◽  
pp. 707-716 ◽  
Author(s):  
Feng Xu ◽  
Peiying Liu ◽  
Juan M Pascual ◽  
Guanghua Xiao ◽  
Hao Huang ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Oxidative Metabolism ◽  
Acute Effect ◽  
Blood Oxygenation ◽  
Effect Of Glucose

scholarly journals A realistic flow phantom model of the carotid artery in preterm infants for training and research

Ultrasound ◽  
2020 ◽  
Vol 28 (3) ◽  
pp. 145-154
Author(s):  
Sujith Pereira ◽  
Jonathan Reeves ◽  
Malcolm Birch ◽  
Sakthi Finton-James ◽  
Komal Verma ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Carotid Artery ◽  
Preterm Infants ◽  
Pulsatile Flow ◽  
Vessel Diameter ◽  
Flow Measurements ◽  
Phantom Model ◽  
Flow Phantom ◽  
Volume Measurements

Introduction Cerebral blood flow is increasingly monitored in preterm infants. Doppler ultrasound of the carotid artery is a widely available method but is operator dependent. Our aim was to design and produce a realistic flow phantom model of the carotid artery of preterm infants. Methods Data from cerebral blood flow measurements using Doppler ultrasound of the right common carotid artery from 21 premature newborn infants were used to produce a Doppler flow phantom model with three different vessel diameters. Vessel diameter, continuous and pulsatile flow volume measurements were performed by two blinded observers (with more than eight and 20 years of experience). Results Vessel diameter measurements using the phantom were underestimated by 7%. Continuous flow volume measurements were overestimated by 7% by both observers (observer 1 mean difference 1.5 ± 1.96 SD −3.3 to 6.3 ml/min versus observer 2, 1.9 ± 1.96 SD −3.6 to 7.4 ml/min). Pulsatile flow measurements were overestimated by 12.6% by observer 1 (2.7 ± 1.96 SD −0.6 to 5.9 ml/min) and by 7.8% by observer 2 (1.7 ± 1.96 SD −1.6 to 4.9 ml/min). There was good interobserver and intraobserver reliability for the majority of measurements using continuous and pulsatile flow. Conclusion It is feasible to produce a realistic flow phantom model of the neonatal carotid artery of preterm infants. Diameter measurements were underestimated and flow measurements were overestimated. These errors fell within acceptable limits for in vivo measurements. If these limitations were related to materials, this could be explored using a wall-less model. The flow phantom could be utilised for research and training clinicians in measuring cerebral blood flow using the carotid artery in this vulnerable group of infants.

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