Residential Radon Exposure and Lung Cancer in Sweden

1994 ◽  
Vol 330 (3) ◽  
pp. 159-164 ◽  
Author(s):  
Goran Pershagen ◽  
Gustav Akerblom ◽  
Olav Axelson ◽  
Bertil Clavensjo ◽  
Lena Damber ◽  
...  
2021 ◽  
pp. 111372
Author(s):  
Alberto Ruano-Ravina ◽  
Leonor Varela Lema ◽  
Marta García Talavera ◽  
Montserrat García Gómez ◽  
Santiago González Muñoz ◽  
...  

2008 ◽  
Vol 94 (3) ◽  
pp. 228-241 ◽  
Author(s):  
Richard E. Thompson ◽  
Donald F. Nelson ◽  
Joel H. Popkin ◽  
Zenaida Popkin

2001 ◽  
Vol 272 (1-3) ◽  
pp. 43-51 ◽  
Author(s):  
L Tomášek ◽  
E Kunz ◽  
T Müller ◽  
J Hůlka ◽  
A Heribanová ◽  
...  

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e20566-e20566
Author(s):  
Angeles Rodriguez Martinez ◽  
Alberto Ruano

e20566 Background: Residential radon is the second most important risk factor for lung cancer. We aim to asses the effect of residential radon exposure on the risk of SCLC in general population. Methods: A multicentric hospital-based case-control study was designed including 10 hospitals from Spain and Portugal. Incident cases with pathological diagnosis of SCLC were prospectively recruited. Controls consisted in patients undergoing non-complex surgery unrelated to tobacco consumption. All study participants were sent a radon detector. Results: A total of 375 cases and 902 controls were recruited. 24.5% of cases were women. The median age at diagnosis was 66 for cases. 6.4% of the cases were younger than 50 years. Tobacco consumption was higher in cases compared to controls. Residential radon concentrations were higher than 147 Bq/m3 in 161 SCLC cases (42.9%). Median residential radon concentration was also higher in SCLC cases compared to controls (152.5 Bq/m3 vs 142 Bq/m3). Those people exposed to more than 147 Bq/m3 and heavy smokers showed an OR of 72,62 (95%CI 17.95 - 499.41) compared to never-smokers with less than 50 Bq/m3. Conclusions: radon exposure seems to increase the risk of small cell lung cancer. There is a significant lung cancer risk departing from 148 Bq/m3 and there is also a linear dose-response pattern. Tobacco consumption may also produce an important effect modification for radon exposure. Those individuals exposed to high radon concentrations and heavy smokers can have a very high risk of this cancer type compared with their low exposed and never-smoking counterparts. It is necessary to increase radon awareness among citizens and administrations in order they can establish the necessary protective and mitigation measures against residential radon. Effect modification between residential radon exposure and tobacco consumption on the risk of small cell lung cancer.[Table: see text]


1992 ◽  
Vol 63 (2) ◽  
pp. 179-186 ◽  
Author(s):  
Göran Pershagen ◽  
Zhong-Hua Liang ◽  
Zdenek Hrubec ◽  
Christer Svensson ◽  
John D. Boice

Author(s):  
Eung Joo Park ◽  
Hokyou Lee ◽  
Hyeon Chang Kim ◽  
Seung Soo Sheen ◽  
Sang Baek Koh ◽  
...  

Residential radon exposure and cigarette smoking are the two most important risk factors for lung cancer. The combined effects thereof were evaluated in a multi-center matched case-control study in South Korea. A total of 1038 participants were included, comprising 519 non-small cell lung cancer cases and 519 age- and sex- matched community-based controls. Residential radon levels were measured for all participants. Multivariate logistic regression was used to calculate odds ratios (OR) for lung cancer according to radon exposure (high ≥ 100 Bq/m3 vs. low < 100 Bq/m3), smoking status, and combinations of the two after adjusting for age, sex, indoor hours, and other housing information. The median age of the participants was 64 years, and 51.3% were women. The adjusted ORs (95% confidence intervals [CIs]) for high radon and cigarette smoking were 1.56 (1.03–2.37) and 2.53 (1.60–3.99), respectively. When stratified according to combinations of radon exposure and smoking status, the adjusted ORs (95% CIs) for lung cancer in high-radon non-smokers, low-radon smokers, and high-radon smokers were 1.40 (0.81–2.43), 2.42 (1.49–3.92), and 4.27 (2.14–8.52), respectively, with reference to low-radon non-smokers. Both residential radon and cigarette smoking were associated with increased odds for lung cancer, and the difference in ORs according to radon exposure was much greater in smokers than in non-smokers.


CMAJ Open ◽  
2017 ◽  
Vol 5 (2) ◽  
pp. E529-E534 ◽  
Author(s):  
Anne Grundy ◽  
Kevin Brand ◽  
Farah Khandwala ◽  
Abbey Poirier ◽  
Sierra Tamminen ◽  
...  

Epidemiology ◽  
1998 ◽  
Vol 9 (Supplement) ◽  
pp. S108 ◽  
Author(s):  
S Darby ◽  
E Whitley ◽  
P Silcocks ◽  
B Thakrar ◽  
M Green ◽  
...  

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