The association between respiratory viruses and symptoms in 2-week-old infants at high risk for asthma and allergy

2001 ◽  
Vol 138 (6) ◽  
pp. 831-837 ◽  
Author(s):  
Richard G. Hegele ◽  
Homa Y. Ahmad ◽  
Allan B. Becker ◽  
Helen Dimich-Ward ◽  
Alexander C. Ferguson ◽  
...  
Keyword(s):  
High Risk ◽  
Respiratory Viruses ◽  
Asthma And Allergy

scholarly journals Predicting SARS-CoV-2 infections for children and youth with single symptom screening

2021 ◽  
Author(s):  
Richard J. Webster ◽  
Deepti Reddy ◽  
Mary-Ann Harrison ◽  
Ken J. Farion ◽  
Jacqueline Wilmore ◽  
...  
Keyword(s):  
High Risk ◽  
Predictive Value ◽  
Relative Frequency ◽  
Respiratory Viruses ◽  
Children And Youth ◽  
Age Group ◽  
Local Factors ◽  
Cough Headache ◽  
Symptom Screening ◽  
Assessment Centre

AbstractSymptom-based SARS-CoV-2 screening and testing decisions in children have important implications on daycare and school exclusion policies. Single symptoms account for a substantial volume of testing and disruption to in-person learning and childcare, yet their predictive value is unclear, given the clinical overlap with other circulating respiratory viruses and non-infectious etiologies. We aimed to determine the relative frequency and predictive value of single symptoms for paediatric SARS-CoV-2 infections from an Ottawa COVID-19 assessment centre from October 2020 through April 2021.Overall, 46.3% (n=10,688) of pediatric encounters were for single symptoms, and 2.7% of these tested positive. The most common presenting single symptoms were rhinorrhea (31.8%), cough (17.4%) and fever (14.0%). Among children with high-risk exposures children in each age group, the following single symptoms had a higher proportion of positive SARS-CoV-2 cases compared to no symptoms; fever and fatigue (0-4 years); fever, cough, headache, and rhinorrhea (5-12 years); fever, loss of taste or smell, headache, rhinorrhea, sore throat, and cough (13-17 years). There was no evidence that the single symptom of either rhinorrhea or cough predicted SARS-CoV-2 infections among 0-4 year olds, despite accounting for a large volume (61.1%) of single symptom presentations in the absence of high-risk exposures.Symptom-based screening needs to be responsive to changes in evidence and local factors, including the expected resurgence of other respiratory viruses following relaxation of social distancing/masking, to reduce infection-related risks in schools and daycare settings.

Exhaled NO and Allergen-induced Cytokine Production from PBMCs in Children at High Risk for Asthma and Allergy

2010 ◽  
Vol 125 (2) ◽  
pp. AB110
Author(s):  
J.E. Sordillo ◽  
T. Webb ◽  
E. Hoffman ◽  
R. Kelly ◽  
D.K. Milton ◽  
...  
Keyword(s):  
High Risk ◽  
Cytokine Production ◽  
Exhaled No ◽  
Asthma And Allergy

scholarly journals SARS-CoV-2 infection of BNT162b2(mRNA)-vaccinated individuals is not restricted to variants of concern or high-risk exposure environments

2021 ◽  
Author(s):  
Brittany Rife Magalis ◽  
Carla Mavian ◽  
Massimiliano Tagliamonte ◽  
Shannan Rich ◽  
Melanie Cash ◽  
...  
Keyword(s):  
High Risk ◽  
Low Frequency ◽  
Respiratory Viruses ◽  
Vaccination Status ◽  
Risk Exposure ◽  
Surrounding Area ◽  
Vaccine Protection ◽  
Genetic Sequencing ◽  
Household Transmission ◽  
Alachua County

The emergence of SARS-CoV-2 variants of concern (VOC) has raised questions regarding the extent of protection of currently implemented vaccines. Ten "vaccination breakthrough" infections were identified in Alachua County, Florida, among individuals fully vaccinated with the BNT162b2 mRNA vaccine as a result of social or household transmission. Eight individuals presented mild symptoms in the absence of infection with other common respiratory viruses, confirmed using viral genetic sequencing. SARS-CoV-2 genomes were successfully generated for five of the vaccine breakthroughs and 399 individuals in the surrounding area and were included for reference-based phylogenetic investigation. These five individuals were characterized by infection with both VOCs and low-frequency variants present within the surrounding population. Mutations in the Spike protein were consistent with their respective circulating lineages, with the exception of a viable, low-frequency (approximately 1%) B.1.1.7 mutation, which we describe as a mutation of potential concern. The findings indicate that in cases of limited vaccine protection, infection is not restricted to VOCs or high-risk settings, highlighting the critical need for continued testing and monitoring of infection among individuals regardless of vaccination status.

A Community Based High Risk Register for Hearing Loss

1982 ◽  
Vol 47 (4) ◽  
pp. 373-375 ◽  
Author(s):  
James L. Fitch ◽  
Thomas F. Williams ◽  
Josephine E. Etienne
Keyword(s):  
Hearing Loss ◽  
System Identification ◽  
High Risk ◽  
Language Learning ◽  
Education Program ◽  
Communication System ◽  
Auditory Signal ◽  
Early Age ◽  
Community Based ◽  
Children With Hearing Loss

The critical need to identify children with hearing loss and provide treatment at the earliest possible age has become increasingly apparent in recent years (Northern & Downs, 1978). Reduction of the auditory signal during the critical language-learning period can severely limit the child's potential for developing a complete, effective communication system. Identification and treatment of children having handicapping conditions at an early age has gained impetus through the Handicapped Children's Early Education Program (HCEEP) projects funded by the Bureau of Education for the Handicapped (BEH).

A Community Based High Risk Register for Hearing Loss

1983 ◽  
Vol 48 (1) ◽  
pp. 110-110
Keyword(s):  
Hearing Loss ◽  
High Risk ◽  
Community Based

For the November 1982 JSHD article, "A Community Based High Risk Register for Hearing Loss," the author would like to acknowledge three additional individuals who made valuable contributions to the study. They are Marie Carrier, Gene Lyon, and Bobbie Robertson.

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