Continuous Flow Photochemistry for the Rapid and Selective Synthesis of 2’-Deoxy and 2’,3’-Dideoxynucleosides
Keyword(s):
A new photochemical flow reactor has been developed for the photo-induced electron-transfer deoxygenation reaction to produce 2′-deoxy and 2′,3′-dideoxynucleosides. The continuous flow format significantly improved both the efficiency and selectivity of the reaction, with the streamlined multi-step sequence directly furnishing the highly desired unprotected deoxynucleosides.
2020 ◽
Vol 8
(35)
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pp. 13195-13205
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2019 ◽
Vol 18
(2)
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pp. 314-318
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Keyword(s):
2020 ◽
Vol 295
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pp. 122291
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2017 ◽
Vol 115
(3)
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pp. 606-616
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2006 ◽
Vol 691
(24-25)
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pp. 5197-5203
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