Increasing chlamydia diagnoses but little change in hospitalisations for ectopic pregnancy and infertility among women in New South Wales from 2001 to 2008

Sexual Health ◽  
2012 ◽  
Vol 9 (4) ◽  
pp. 355 ◽  
Author(s):  
Bette Liu ◽  
Basil Donovan ◽  
Jim Parker ◽  
Rebecca Guy ◽  
Jane Hocking ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Ectopic Pregnancy ◽  
Time Trends ◽  
New South ◽  
New South Wales ◽  
Female Infertility ◽  
Hospitalisation Rate ◽  
Routinely Collected Data ◽  
South Wales ◽  
Probabilistic Linkage

Background As genital chlamydia (Chlamydia trachomatis) notifications have increased in Australia, time trends in hospitalisations for ectopic pregnancy and female infertility between 2001 and 2008 in New South Wales (NSW), Australia, and their relationship to trends in chlamydia notifications in women were assessed. Methods: Annual rates of chlamydia notification, and hospitalisations for female infertility or ectopic pregnancy in women aged 15–44 years in NSW were calculated using routinely collected data. Chlamydia notifications and hospital separations occurring within each year belonging to the same woman were linked using probabilistic linkage of identifiers so that multiple notifications and admissions for one woman in each calendar year were only counted once. Results: From 2001 to 2008, the annual rate of chlamydia diagnoses in women increased from 157 to 477 per 100 000 population (Ptrend < 0.001). Over the same period, the annual hospitalisation rate for women with an ectopic pregnancy decreased from 14.3 to 12.6 per 1000 births (Ptrend < 0.001). This decrease was mostly in women aged 25–44 years, with no appreciable fall in women aged 15–24 years (Ptrend = 0.8). Meanwhile, the hospitalisation rate for women with infertility of female origin did not follow a consistent trend: between 2001 and 2008, it fluctuated between a low of 479 and a high of 554 per 10 000 women who were seeking pregnancy. Conclusions: These trends in ectopic pregnancy and female infertility suggest that the large increase in chlamydia notifications may not reflect hospitalisations for these two proposed chlamydia-related sequelae.

Changes in testing methods for genital Chlamydia trachomatis in New South Wales, Australia, 1999 to 2002

Sexual Health ◽  
2005 ◽  
Vol 2 (4) ◽  
pp. 251 ◽  
Author(s):  
Marcus Y. Chen ◽  
Basil Donovan
Keyword(s):  
Chlamydia Trachomatis ◽  
Relative Frequency ◽  
New South ◽  
New South Wales ◽  
Health Department ◽  
Laboratory Method ◽  
Testing Methods ◽  
Chlamydia Trachomatis Infection ◽  
South Wales ◽  
Rapid Shift

Background: Over the last decade, significant advances have occurred in the area of chlamydia diagnostics. The relative frequency of different testing methods employed in the diagnosis of Chlamydia trachomatis infection in New South Wales has not been previously reported. Methods: Testing methods—both laboratory method and specimen type—employed in the diagnosis of chlamydia cases notified in New South Wales between 1999 and 2002 were collated from Health Department records. Results: During a period of increasing notifications, the proportion of men diagnosed with C. trachomatis using nucleic acid tests (NATs) increased from 36% in 1999 to 90% in 2002. Among women, the proportion diagnosed using NATs increased from 42% in 1999 to 92% in 2002. Urine samples were consistently used in the diagnosis of two-thirds of the men, and one-third of the women. Conclusion: Between 1999 and 2002, a rapid shift towards NATs for genital C. trachomatis took place in New South Wales.

57. GENOTYPING OF UROGENITAL CHLAMYDIA TRACHOMATIS IN REGIONAL NEW SOUTH WALES, AUSTRALIA

Sexual Health ◽  
2007 ◽  
Vol 4 (4) ◽  
pp. 306
Author(s):  
D. Mossman ◽  
C. Ooi ◽  
M. Loewenthal ◽  
M. Boyle
Keyword(s):  
Chlamydia Trachomatis ◽  
Older Patients ◽  
New South ◽  
Genotypic Variation ◽  
New South Wales ◽  
Genotype Frequency ◽  
Sexual Networks ◽  
Genotype Analysis ◽  
South Wales ◽  
Significant Difference

Background: Chlamydia Trachomatis is one of the most common sexually transmitted infections in Australia and world wide. This study was undertaken to map the frequency of Chlamydia genotypes in regional New South Wales (NSW), Australia, to explore the potential utility of genotype analysis in defining local sexual networks, and to investigate whether patterns of genotype frequency are correlated with demographic factors, including age and gender. Methods: We studied 204 urine samples infected with Chlamydia trachomatis, as determined by PCR analysis using the COBAS Amplicor system. Samples were collected from wide geographic area of regional New South Wales (Hunter, New England, Northern Rivers, South Eastern New South Wales). Sequencing and genotyping were performed after nested PCR of the omp1 gene. Results: Genotype E was found in 42.6% of infections, with genotypes F (23.5%) and G (16.7%) other common causes of infection. Mixed infection occurred in only 3 cases. There was no significant difference in genotype frequency based on gender or geographic location. There was a significant difference in gender frequency based on patient age, with older patients significantly more likely to demonstrate infection with genotype G (mean age (years) 23.7+/-7.29 sd, E: 21.7 +/-5.7 sd; G: 28.9; sd 10.18; p�=�0.022). Conclusions: There was no significant difference in genotype frequency in the various regions of New South Wales, suggesting genotype analysis is of limited use in defining sexual networks in regional NSW. The finding of a higher frequency of genotype G in older patients raises the possibility that genotypic variation may be driven by immune responses to genotypes that occur more frequently at a younger age. These results may have implications for the future design of a chlamydial vaccine.

Genotyping of Urogenital Chlamydia trachomatis in Regional New South Wales, Australia

2008 ◽  
Vol 35 (6) ◽  
pp. 614-616 ◽  
Author(s):  
David Mossman ◽  
Kenneth W. Beagley ◽  
Alan L. Landay ◽  
Mark Loewenthal ◽  
Catriona Ooi ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
New South ◽  
New South Wales ◽  
South Wales

Chlamydia trachomatis infection in the family planning clinical setting across New South Wales

Sexual Health ◽  
2006 ◽  
Vol 3 (1) ◽  
pp. 15 ◽  
Author(s):  
Deborah J. Bateson ◽  
Edith Weisberg ◽  
Harpreet Lota
Keyword(s):  
Family Planning ◽  
Chlamydia Trachomatis ◽  
New South ◽  
New South Wales ◽  
Oral Contraceptive Pill ◽  
Chlamydia Trachomatis Infection ◽  
The Past ◽  
South Wales ◽  
Sexually Transmissible Infections ◽  
The Family

Background: Following a small pilot study in 2003, a study was set up to determine the prevalence of genital Chlamydia trachomatis infection in young women presenting to Family Planning NSW centres across New South Wales and to evaluate the characteristics of those infected. Methods: A cross-sectional survey of 621 consecutive women aged from 16 to 24 years was carried out over a 3-month period in 2004 at five Family Planning NSW centres. Urine samples were tested for C. trachomatis using the polymerase chain reaction (PCR) method. Women with a positive result were reviewed and treated. Results: Of 925 eligible clients, 621 (67%) were recruited to the study. Chlamydia trachomatis was detected in 35 of the 621 recruits (5.6%, 95% CI 3.8–7.4). The prevalence at the Hunter centre was significantly higher than the combined prevalence at the other four participating centres (9.7% compared with 3.9%; P = 0.008). Two characteristics were identified as independent predictors of infection in this study: ‘reporting a recent change of partner in the past three months’ (crude odds ratio (OR) 3.33, 95% CI 1.67–6.64) and ‘reporting three or more partners in the past year’ (crude OR 3.69, 95% CI 1.83–7.46). Reported condom use, a history of one or more sexually transmissible infections and current combined oral contraceptive pill use were not associated with infection in this study. Conclusions: The prevalence of C. trachomatis infection is sufficiently high to support targeted testing of 16–24-year-old women in the Family Planning NSW setting and informs the development of a national screening strategy.

Trends in the incidence of ectopic pregnancy in New South Wales between 1990–1998

2001 ◽  
Vol 41 (4) ◽  
pp. 436-438 ◽  
Author(s):  
Soufiane Boufous ◽  
Maria Quartararo ◽  
Mohammed Mohsin ◽  
Jim Parker
Keyword(s):  
Ectopic Pregnancy ◽  
New South ◽  
New South Wales ◽  
South Wales

Chlamydia trachomatis infection among antenatal women in remote far west New South Wales, Australia

Sexual Health ◽  
2007 ◽  
Vol 4 (2) ◽  
pp. 139 ◽  
Author(s):  
Jo-ann Lenton ◽  
Eleanor Freedman ◽  
Kristie Hoskin ◽  
Vickie Knight ◽  
Darriea Turley ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Perceived Risk ◽  
New South ◽  
New South Wales ◽  
Cross Sectional Study ◽  
Indigenous Women ◽  
Indigenous Status ◽  
Cross Sectional ◽  
Chlamydia Trachomatis Infection ◽  
South Wales

Background: A prospective, cross-sectional study was undertaken of pregnant women attending antenatal services in the remote far west of New South Wales, Australia, between October 2004 and May 2006. Of 420 eligible women, 218 (52%) participated in the study. Six women (2.7%; 95% CI: 1.0–5.9) tested positive for Chlamydia trachomatis. The prevalence among pregnant, Indigenous women (n = 44) was 9.1% (95% CI: 2.5–21.7). Infection was significantly associated with Indigenous status (P = 0.003) and self-perceived risk for chlamydia (P = 0.05). Pregnant Indigenous women in remote areas may be at higher risk for chlamydia and targeted screening of this group should be considered.

scholarly journals Birthplace in New South Wales, Australia: an analysis of perinatal outcomes using routinely collected data

2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Caroline SE Homer ◽  
Charlene Thornton ◽  
Vanessa L Scarf ◽  
David A Ellwood ◽  
Jeremy JN Oats ◽  
...  
Keyword(s):  
New South ◽  
New South Wales ◽  
Perinatal Outcomes ◽  
Routinely Collected Data ◽  
South Wales

Prevalence of Chlamydia trachomatis infection among 'high risk' young people in New South Wales

Sexual Health ◽  
2006 ◽  
Vol 3 (4) ◽  
pp. 253 ◽  
Author(s):  
Melissa Kang ◽  
Arlie Rochford ◽  
Victoria Johnston ◽  
Julie Jackson ◽  
Ellie Freedman ◽  
...  
Keyword(s):  
High Risk ◽  
Chlamydia Trachomatis ◽  
Young People ◽  
New South ◽  
New South Wales ◽  
Contact Tracing ◽  
Sexually Active ◽  
Chlamydia Trachomatis Infection ◽  
South Wales ◽  
Sexually Transmissible Infections

International research on homeless adolescents has found that incidence and prevalence of sexually transmissible infections is relatively high. This study reports on a chlamydia prevalence survey conducted among high-risk young people (14–25 years) in New South Wales. The participants were recruited from youth health centres, which target homeless and high-risk youth. Of 333 clients (42.6% male), 84.1% were sexually active and mean number of sexual partners over the preceding 3 months was 1.4. Among sexually active participants, 24.6% claimed to use condoms always and 25% never. Sixteen of 274 available urine samples tested positive for Chlamydia trachomatis infection. Further research is warranted to better define high-risk groups and clarify the nature of associations between various factors impacting on sexual health. Most importantly, research is now called for into effective strategies for engaging and attracting young people to screening, treatment and contact tracing.

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