Spatial restriction of receptor tyrosine kinase activity through a polarized endocytic cycle controls border cell migration

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1010795108 ◽

2010 ◽

Vol 107 (52) ◽

pp. 22558-22563 ◽

Author(s):

G. Assaker ◽

D. Ramel ◽

S. K. Wculek ◽

M. Gonzalez-Gaitan ◽

G. Emery

Keyword(s):

Cell Migration ◽

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Tyrosine Kinase Activity ◽

Border Cell ◽

Border Cell Migration

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Regulated Breathless receptor tyrosine kinase activity required to pattern cell migration and branching in the Drosophila tracheal system.

Genes & Development ◽

10.1101/gad.10.22.2912 ◽

1996 ◽

Vol 10 (22) ◽

pp. 2912-2921 ◽

Author(s):

T Lee ◽

N Hacohen ◽

M Krasnow ◽

D J Montell

Keyword(s):

Cell Migration ◽

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Tyrosine Kinase Activity ◽

Tracheal System

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Insulin receptor tyrosine kinase activity is reduced in type-2 (non-insulin-dependent) diabetes but not in obesity

Acta Endocrinologica ◽

10.1530/acta.0.114s183 ◽

1987 ◽

Vol 116 (3_Suppl) ◽

pp. S183

Author(s):

H.H. KLEIN ◽

G.R. FREIDENBERG ◽

R.R. HENRY ◽

J.M. OLEFSKY

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Insulin Dependent Diabetes ◽

Tyrosine Kinase Activity ◽

Insulin Receptor Tyrosine Kinase ◽

Insulin Dependent

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Effect of streptozocin-induced diabetes on insulin-receptor tyrosine kinase activity in obese Zucker rats

Diabetes ◽

10.2337/diabetes.39.5.619 ◽

1990 ◽

Vol 39 (5) ◽

pp. 619-625 ◽

Author(s):

L. J. Slieker ◽

E. F. Roberts ◽

W. N. Shaw ◽

W. T. Johnson

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Zucker Rats ◽

Tyrosine Kinase Activity ◽

Insulin Receptor Tyrosine Kinase ◽

Obese Zucker Rats

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Substitution of isoleucine for methionine at position 1153 in the beta-subunit of the human insulin receptor. A mutation that impairs receptor tyrosine kinase activity, receptor endocytosis, and insulin action.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)42456-8 ◽

1992 ◽

Vol 267 (12) ◽

pp. 8383-8389 ◽

Author(s):

A Cama ◽

M.J. Quon ◽

M de la Luz Sierra ◽

S.I. Taylor

Keyword(s):

Tyrosine Kinase ◽

Insulin Receptor ◽

Human Insulin ◽

Receptor Tyrosine Kinase ◽

Insulin Action ◽

Kinase Activity ◽

Beta Subunit ◽

Tyrosine Kinase Activity ◽

Receptor Endocytosis ◽

Human Insulin Receptor

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Amiloride directly inhibits growth factor receptor tyrosine kinase activity.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)89586-2 ◽

1985 ◽

Vol 260 (4) ◽

pp. 2543-2551 ◽

Author(s):

R J Davis ◽

M P Czech

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Growth Factor Receptor ◽

Tyrosine Kinase Activity

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A specific type of ganglioside as a modulator of insulin-dependent cell growth and insulin receptor tyrosine kinase activity

Journal of Biological Chemistry ◽

10.1016/s0021-9258(20)64355-1 ◽

1991 ◽

Vol 266 (7) ◽

pp. 4531-4537

Author(s):

H Nojiri ◽

M Stroud ◽

S Hakomori

Keyword(s):

Cell Growth ◽

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Tyrosine Kinase Activity ◽

Insulin Receptor Tyrosine Kinase ◽

Dependent Cell ◽

Insulin Dependent

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A combinatorial in silico and cellular approach to identify a new class of compounds that target VEGFR2 receptor tyrosine kinase activity and angiogenesis

British Journal of Pharmacology ◽

10.1111/j.1476-5381.2011.01801.x ◽

2012 ◽

Vol 166 (2) ◽

pp. 737-748 ◽

Author(s):

J Kankanala ◽

AM Latham ◽

AP Johnson ◽

S Homer-Vanniasinkam ◽

CWG Fishwick ◽

...

Keyword(s):

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

In Silico ◽

Kinase Activity ◽

Tyrosine Kinase Activity ◽

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Specific Inhibition of Insulin-Like Growth Factor-1 and Insulin Receptor Tyrosine Kinase Activity and Biological Function by Tyrphostins

Endocrinology ◽

10.1210/endo.138.4.5092 ◽

1997 ◽

Vol 138 (4) ◽

pp. 1427-1433 ◽

Author(s):

Marcelina Párrizas ◽

Aviv Gazit ◽

Alexander Levitzki ◽

Efrat Wertheimer ◽

Derek LeRoith

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Insulin Receptor ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Biological Function ◽

Specific Inhibition ◽

Insulin Like Growth Factor ◽

Tyrosine Kinase Activity ◽

Insulin Receptor Tyrosine Kinase

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Extracellular domain determinants of LET-23 (EGF) receptor tyrosine kinase activity in Caenorhabditis elegans

Oncogene ◽

10.1038/sj.onc.1206648 ◽

2003 ◽

Vol 22 (35) ◽

pp. 5471-5480 ◽

Author(s):

Nadeem Moghal ◽

Paul W Sternberg

Keyword(s):

Caenorhabditis Elegans ◽

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Egf Receptor ◽

Extracellular Domain ◽

Tyrosine Kinase Activity

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Potent quinoxaline-Based inhibitors of PDGF receptor tyrosine kinase activity. Part 2: the synthesis and biological activities of RPR127963 an orally bioavailable inhibitor

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(03)00655-3 ◽

2003 ◽

Vol 13 (18) ◽

pp. 3097-3100 ◽

Author(s):

Wei He ◽

Michael R. Myers ◽

Barbara Hanney ◽

Alfred P. Spada ◽

Glenda Bilder ◽

...

Keyword(s):

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Kinase Activity ◽

Biological Activities ◽

Pdgf Receptor ◽

Tyrosine Kinase Activity ◽

Orally Bioavailable

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