scholarly journals A Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters.

1996 ◽  
Vol 93 (21) ◽  
pp. 11901-11906 ◽  
Author(s):  
N. Shani ◽  
D. Valle
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Atp Binding ◽  
Atp Binding Cassette Transporters ◽  
Atp Binding Cassette

scholarly journals Stimulation of Cholesterol Excretion by the Liver X Receptor Agonist Requires ATP-binding Cassette Transporters G5 and G8

2003 ◽  
Vol 278 (18) ◽  
pp. 15565-15570 ◽  
Author(s):  
Liqing Yu ◽  
Jennifer York ◽  
Klaus von Bergmann ◽  
Dieter Lutjohann ◽  
Jonathan C. Cohen ◽  
...  
Keyword(s):  
Receptor Agonist ◽  
Liver X Receptor ◽  
Atp Binding ◽  
Atp Binding Cassette Transporters ◽  
Cholesterol Excretion ◽  
Liver X Receptor Agonist ◽  
Stimulation Of ◽  
Atp Binding Cassette

scholarly journals The capacity of Listeria monocytogenes mutants with in-frame deletions in putative ATP-binding cassette transporters to form biofilms and comparison with the wild type

2014 ◽  
Vol 3 (1) ◽  
Author(s):  
Marina Ceruso ◽  
Pina Fratamico ◽  
Claudia Chirollo ◽  
Rosanna Taglialatela ◽  
Maria Luisa Cortesi ◽  
...  
Keyword(s):  
Listeria Monocytogenes ◽  
Atp Binding ◽  
Wild Type ◽  
Atp Binding Cassette Transporters ◽  
Atp Binding Cassette

scholarly journals Expression of an ATP-binding cassette transporter-encoding gene (YOR1) is required for oligomycin resistance in Saccharomyces cerevisiae.

1995 ◽  
Vol 15 (12) ◽  
pp. 6875-6883 ◽  
Author(s):  
D J Katzmann ◽  
T C Hallstrom ◽  
M Voet ◽  
W Wysock ◽  
J Golin ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Fusion Gene ◽  
Sequence Similarity ◽  
Yeast Cells ◽  
Atp Binding ◽  
Zinc Cluster ◽  
Atp Binding Cassette Transporter ◽  
Transporter Family ◽  
Encoding Gene ◽  
Atp Binding Cassette

Semidominant mutations in the PDR1 or PDR3 gene lead to elevated resistance to cycloheximide and oligomycin. PDR1 and PDR3 have been demonstrated to encode zinc cluster transcription factors. Cycloheximide resistance mediated by PDR1 and PDR3 requires the presence of the PDR5 membrane transporter-encoding gene. However, PDR5 is not required for oligomycin resistance. Here, we isolated a gene that is necessary for PDR1- and PDR3-mediated oligomycin resistance. This locus, designated YOR1, causes a dramatic elevation in oligomycin resistance when present in multiple copies. A yor1 strain exhibits oligomycin hypersensitivity relative to an isogenic wild-type strain. In addition, loss of the YOR1 gene blocks the elevation in oligomycin resistance normally conferred by mutant forms of PDR1 or PDR3. The YOR1 gene product is predicted to be a member of the ATP-binding cassette transporter family of membrane proteins. Computer alignment indicates that Yor1p shows striking sequence similarity with multidrug resistance-associated protein, Saccharomyces cerevisiae Ycf1p, and the cystic fibrosis transmembrane conductance regulator. Use of a YOR1-lacZ fusion gene indicates that YOR1 expression is responsive to PDR1 and PDR3. While PDR5 expression is strictly dependent on the presence of PDR1 or PDR3, control of YOR1 expression has a significant PDR1/PDR3-independent component. Taken together, these data indicate that YOR1 provides the link between transcriptional regulation by PDR1 and PDR3 and oligomycin resistance of yeast cells.

scholarly journals Expression profiling of ATP-binding cassette transporters in childhood T-cell acute lymphoblastic leukemia

2006 ◽  
Vol 5 (8) ◽  
pp. 1986-1994 ◽  
Author(s):  
Thomas Efferth ◽  
Jean-Pierre Gillet ◽  
Axel Sauerbrey ◽  
Felix Zintl ◽  
Vincent Bertholet ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
T Cell ◽  
Expression Profiling ◽  
Lymphoblastic Leukemia ◽  
Atp Binding ◽  
Atp Binding Cassette Transporters ◽  
Cell Acute Lymphoblastic Leukemia ◽  
Atp Binding Cassette

scholarly journals Endocrine Disruptors Differentially Target ATP-Binding Cassette Transporters in the Blood-Testis Barrier and Affect Leydig Cell Testosterone Secretion In Vitro

2013 ◽  
Vol 136 (2) ◽  
pp. 382-391 ◽  
Author(s):  
Anita C. A. Dankers ◽  
Maarke J. E. Roelofs ◽  
Aldert H. Piersma ◽  
Fred C. G. J. Sweep ◽  
Frans G. M. Russel ◽  
...  
Keyword(s):  
Endocrine Disruptors ◽  
Leydig Cell ◽  
Atp Binding ◽  
Testosterone Secretion ◽  
Atp Binding Cassette Transporters ◽  
Blood Testis Barrier ◽  
Atp Binding Cassette

scholarly journals Characterization and functional analysis of the nucleotide binding fold in human peroxisomal ATP binding cassette transporters

FEBS Letters ◽  
2001 ◽  
Vol 492 (1-2) ◽  
pp. 66-72 ◽  
Author(s):  
Peter Roerig ◽  
Peter Mayerhofer ◽  
Andreas Holzinger ◽  
Jutta Gärtner
Keyword(s):  
Functional Analysis ◽  
Nucleotide Binding ◽  
Atp Binding ◽  
Atp Binding Cassette Transporters ◽  
Atp Binding Cassette

Relation between hepatic expression of ATP-binding cassette transporters G5 and G8 and biliary cholesterol secretion in mice

2003 ◽  
Vol 38 (6) ◽  
pp. 710-716 ◽  
Author(s):  
Astrid Kosters ◽  
Raoul J.J.M. Frijters ◽  
Frank G. Schaap ◽  
Edwin Vink ◽  
Torsten Plösch ◽  
...  
Keyword(s):  
Atp Binding ◽  
Biliary Cholesterol ◽  
Hepatic Expression ◽  
Atp Binding Cassette Transporters ◽  
Biliary Cholesterol Secretion ◽  
Cholesterol Secretion ◽  
Atp Binding Cassette
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