Gqprotein-induced apoptosis is mediated by AKT kinase inhibition that leads to protein kinase C-induced c-Jun N-terminal kinase activation.

Ido Ben-Ami; Zhong Yao; Zvi Naor; Rony Seger

doi:10.1074/jbc.a111.247726

Gqprotein-induced apoptosis is mediated by AKT kinase inhibition that leads to protein kinase C-induced c-Jun N-terminal kinase activation.

Journal of Biological Chemistry ◽

10.1074/jbc.a111.247726 ◽

2017 ◽

Vol 292 (21) ◽

pp. 8848-8848

Author(s):

Ido Ben-Ami ◽

Zhong Yao ◽

Zvi Naor ◽

Rony Seger

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Akt Kinase ◽

Kinase Inhibition ◽

Kinase Activation ◽

Kinase C ◽

Induced Apoptosis

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GqProtein-induced Apoptosis Is Mediated by AKT Kinase Inhibition That Leads to Protein Kinase C-induced c-Jun N-terminal Kinase Activation

Journal of Biological Chemistry ◽

10.1074/jbc.m111.247726 ◽

2011 ◽

Vol 286 (35) ◽

pp. 31022-31031 ◽

Cited By ~ 12

Author(s):

Ido Ben-Ami ◽

Zhong Yao ◽

Zvi Naor ◽

Rony Seger

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Akt Kinase ◽

Kinase Inhibition ◽

Kinase Activation ◽

Kinase C ◽

Induced Apoptosis

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Targeting Protein Kinase C (PKC) and Telomerase by Phenethyl Isothiocyanate (PEITC) Sensitizes PC-3 Cells Towards Chemotherapeutic Drug-Induced Apoptosis

Journal of Environmental Pathology Toxicology and Oncology ◽

10.1615/jenvironpatholtoxicoloncol.v28.i4.30 ◽

2009 ◽

Vol 28 (4) ◽

pp. 269-282 ◽

Cited By ~ 24

Author(s):

Sutapa Mukherjee ◽

Rathindra Kumar Bhattacharya ◽

Madhumita Roy

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Phenethyl Isothiocyanate ◽

Chemotherapeutic Drug ◽

Drug Induced ◽

Kinase C ◽

Induced Apoptosis

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2133-P: Protein Kinase C Delta Mediates Cytokine-Induced Apoptosis in the Pancreatic Beta Cell

Diabetes ◽

10.2337/db19-2133-p ◽

2019 ◽

Vol 68 (Supplement 1) ◽

pp. 2133-P

Author(s):

NIKKI L. FARNSWORTH ◽

ROBERT A. PISCOPIO ◽

RICHARD K. BENNINGER

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Beta Cell ◽

Pancreatic Beta Cell ◽

Protein Kinase C Delta ◽

Kinase C ◽

P Protein ◽

Induced Apoptosis

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Role of the kinase activation loop on protein kinase C θ activity and intracellular localisation

FEBS Letters ◽

10.1016/s0014-5793(03)01073-1 ◽

2003 ◽

Vol 554 (1-2) ◽

pp. 35-40 ◽

Cited By ~ 11

Author(s):

Bianca Sparatore ◽

Mario Passalacqua ◽

Marco Pedrazzi ◽

Sabina Ledda ◽

Mauro Patrone ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Activation Loop ◽

Kinase Activation ◽

Kinase C ◽

Intracellular Localisation

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Evidence for Involvement of Mitogen-Activated Protein Kinase, Rather than Stress-Activated Protein Kinase, in Potentiation of 1-β-d-Arabinofuranosylcytosine-Induced Apoptosis by Interruption of Protein Kinase C Signaling

Molecular Pharmacology ◽

10.1124/mol.54.5.844 ◽

1998 ◽

Vol 54 (5) ◽

pp. 844-856 ◽

Cited By ~ 51

Author(s):

W. David Jarvis ◽

Frank A. Fornari ◽

Robert M. Tombes ◽

Ravi K. Erukulla ◽

Robert Bittman ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Mitogen Activated Protein Kinase ◽

Kinase C ◽

Mitogen Activated Protein ◽

Induced Apoptosis

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Involvement of Protein Kinase C in HIV-1 gp120-Induced Apoptosis in Primary Endothelium

JAIDS Journal of Acquired Immune Deficiency Syndromes ◽

10.1097/00126334-200012150-00001 ◽

2000 ◽

Vol 25 (5) ◽

pp. 375-389 ◽

Cited By ~ 19

Author(s):

Ming-Bo Huang ◽

Vincent C. Bond

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Kinase C ◽

Induced Apoptosis ◽

Hiv 1

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Cholecystokinin-stimulated Protein Kinase C-δ Kinase Activation, Tyrosine Phosphorylation, and Translocation Are Mediated by Src Tyrosine Kinases in Pancreatic Acinar Cells

Journal of Biological Chemistry ◽

10.1074/jbc.m303119200 ◽

2003 ◽

Vol 278 (37) ◽

pp. 35220-35230 ◽

Cited By ~ 49

Author(s):

Jose A. Tapia ◽

Luis J. García-Marin ◽

Robert T. Jensen

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Tyrosine Phosphorylation ◽

Tyrosine Kinases ◽

Acinar Cells ◽

Pancreatic Acinar Cells ◽

Kinase Activation ◽

Kinase C ◽

Src Tyrosine Kinases

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Biphasic effect of protein kinase C activators on spontaneous and glucocorticoid-induced apoptosis in primary mouse thymocytes

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ◽

10.1016/s0167-4889(00)00067-7 ◽

2000 ◽

Vol 1497 (3) ◽

pp. 289-296 ◽

Cited By ~ 6

Author(s):

Jörg Rennecke ◽

K.Hartmut Richter ◽

Sabine Häussermann ◽

Luise Stempka ◽

Susanne Strand ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Kinase C ◽

Primary Mouse ◽

Biphasic Effect ◽

Protein Kinase C Activators ◽

Induced Apoptosis

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Helicobacter pylori -induced apoptosis in gastric epithelial cells is blocked by protein kinase C activation

Microbial Pathogenesis ◽

10.1006/mpat.2002.0523 ◽

2002 ◽

Vol 33 (4) ◽

pp. 167-175

Author(s):

Barbara Obst ◽

Silke Schütz ◽

Susanne Ledig ◽

Siegfried Wagner ◽

Winfried Beil

Keyword(s):

Helicobacter Pylori ◽

Protein Kinase C ◽

Protein Kinase ◽

Epithelial Cells ◽

Gastric Epithelial Cells ◽

Kinase C ◽

Induced Apoptosis ◽

Protein Kinase C Activation

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Hypothermia differentially increases extracellular signal-regulated kinase and stress-activated protein kinase/c-Jun terminal kinase activation in the hippocampus during reperfusion after asphyxial cardiac arrest

Neuroscience ◽

10.1016/s0306-4522(00)00169-x ◽

2000 ◽

Vol 98 (4) ◽

pp. 677-685 ◽

Cited By ~ 42

Author(s):

S.D. Hicks ◽

K.T. Parmele ◽

D.B. DeFranco ◽

E. Klann ◽

C.W. Callaway

Keyword(s):

Cardiac Arrest ◽

Protein Kinase C ◽

Protein Kinase ◽

Kinase Activation ◽

Extracellular Signal Regulated Kinase ◽

Kinase C ◽

Extracellular Signal ◽

Asphyxial Cardiac Arrest

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